Nucleolin, a shuttle protein promoting infection of human monocytes by Francisella tularensis. - Archive ouverte HAL Access content directly
Journal Articles PLoS ONE Year : 2010

Nucleolin, a shuttle protein promoting infection of human monocytes by Francisella tularensis.

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Abstract

We herein confirm the importance of nucleolin expression for LVS binding and its specificity as nucleolin is not involved in binding of another intracellular pathogen as L. monocytogenes or an inert particle. Association of nucleolin with F. tularensis during infection continues intracellularly after endocytosis of the bacteria. The present work therefore unravels for the first time the presence of nucleolin in the phagosomal compartment of macrophages.
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inserm-00551286 , version 1 (03-01-2011)

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Monique Barel, Karin Meibom, Alain Charbit. Nucleolin, a shuttle protein promoting infection of human monocytes by Francisella tularensis.. PLoS ONE, 2010, 5 (12), pp.e14193. ⟨10.1371/journal.pone.0014193⟩. ⟨inserm-00551286⟩
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