Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles Circulation Year : 2010

Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats.

Abstract

These results support an effect of HPIs on pulmonary vascular remodeling mediated by inhibition of Akt phosphorylation and consequently of pulmonary artery smooth muscle cell proliferation.
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Dates and versions

inserm-00545885 , version 1 (09-05-2011)

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Guillaume Gary-Bobo, Amal Houssaini, Valerie Amsellem, Dominique Rideau, Pierre Pacaud, et al.. Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats.. Circulation, 2010, 122 (19), pp.1937-47. ⟨10.1161/CIRCULATIONAHA.110.973750⟩. ⟨inserm-00545885⟩
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