Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats. - Archive ouverte HAL Access content directly
Journal Articles Circulation Year : 2010

Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats.

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Abstract

These results support an effect of HPIs on pulmonary vascular remodeling mediated by inhibition of Akt phosphorylation and consequently of pulmonary artery smooth muscle cell proliferation.
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inserm-00545885 , version 1 (09-05-2011)

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Guillaume Gary-Bobo, Amal Houssaini, Valerie Amsellem, Dominique Rideau, Pierre Pacaud, et al.. Effects of HIV protease inhibitors on progression of monocrotaline- and hypoxia-induced pulmonary hypertension in rats.. Circulation, 2010, 122 (19), pp.1937-47. ⟨10.1161/CIRCULATIONAHA.110.973750⟩. ⟨inserm-00545885⟩
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