Distinguishing the relevant features of frequent suicide attempters.: Features of frequent suicide attempters

Jorge Lopez-Castroman 1, * Maria de Las Mercedes Perez-Rodriguez 2 Isabelle Jaussent 3, 4 Analucia Alegria 5, 6 Antonio Artes-Rodriguez 7 Peter Freed 5 Sébastien Guillaume 3, 4 Fabrice Jollant 3, 4 Jose Miguel Leiva-Murillo 7 Alain Malafosse 3, 4 Maria Oquendo 5 Mario De Prado-Cumplido 7 Jeronimo Saiz-Ruiz 6, 8, 9 Enrique Baca-Garcia 1, 5, 6 Philippe Courtet 3, 4
* Auteur correspondant
1 Department of Psychiatry
2 Department of Psychiatry
3 Pathologies du système nerveux : recherche épidémiologique et clinique
4 Urgence et post-urgence psychiatrique
5 Department of Psychiatry
6 Centro de Investigación Biomédica en Red de Salud Mental
7 Department of Signal Theory and Communications
8 Department of Psychiatry
9 Department of Psychiatry
Abstract : BACKGROUND: In spite of the high prevalence of suicide behaviours and the magnitude of the resultant burden, little is known about why individuals reattempt. We aim to investigate the relationships between clinical risk factors and the repetition of suicidal attempts. METHODS: 1349 suicide attempters were consecutively recruited in the Emergency Room (ER) of two academic hospitals in France and Spain. Patients were extensively assessed and demographic and clinical data obtained. Data mining was used to determine the minimal number of variables that blinded the rest in relation to the number of suicide attempts. Using this set, a probabilistic graph ranking relationships with the target variable was constructed. RESULTS: The most common diagnoses among suicide attempters were affective disorders, followed by anxiety disorders. Risk of frequent suicide attempt was highest among middle-aged subjects, and diminished progressively with advancing age of onset at first attempt. Anxiety disorders significantly increased the risk of presenting frequent suicide attempts. Pathway analysis also indicated that frequent suicide attempts were linked to greater odds for alcohol and substance abuse disorders and more intensive treatment. CONCLUSIONS: Novel statistical methods found several clinical features that were associated with a history of frequent suicide attempts. The identified pathways may promote new hypothesis-driven studies of suicide attempts and preventive strategies.
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Article dans une revue
Journal of Psychiatric Research, Elsevier, 2011, 45 (5), pp.619-25. 〈10.1016/j.jpsychires.2010.09.017〉
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Jorge Lopez-Castroman, Maria de Las Mercedes Perez-Rodriguez, Isabelle Jaussent, Analucia Alegria, Antonio Artes-Rodriguez, et al.. Distinguishing the relevant features of frequent suicide attempters.: Features of frequent suicide attempters. Journal of Psychiatric Research, Elsevier, 2011, 45 (5), pp.619-25. 〈10.1016/j.jpsychires.2010.09.017〉. 〈inserm-00539847〉

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