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Gait is associated with an increase in tonic firing of the sub-cuneiform nucleus neurons.

Abstract : In animals, the pedunculopontine (PPN) and the sub-cuneiform (SCU) nuclei located in the upper brainstem are involved during the processing of gait. Similar functional nuclei are suspected in humans but their role in gait is unclear. Here we show that, using extra-cellular recordings of the PPN/SCU region obtained in two parkinsonian patients, the SCU neurons increased their firing rate without modifying their firing pattern during mimicked steps. We conclude that SCU neurons are activated during gait processes.
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https://www.hal.inserm.fr/inserm-00536386
Contributor : Jean-Paul Issartel <>
Submitted on : Tuesday, November 16, 2010 - 10:21:03 AM
Last modification on : Wednesday, November 27, 2019 - 1:48:01 PM

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Brigitte Piallat, Stéphane Chabardès, Napoleon Torres, Valérie Fraix, Laurent Goetz, et al.. Gait is associated with an increase in tonic firing of the sub-cuneiform nucleus neurons.. Neuroscience, Elsevier - International Brain Research Organization, 2009, 158 (4), pp.1201-5. ⟨10.1016/j.neuroscience.2008.10.046⟩. ⟨inserm-00536386⟩

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