Gait is associated with an increase in tonic firing of the sub-cuneiform nucleus neurons.

Brigitte Piallat 1 Stéphane Chabardès 1, 2 Napoleon Torres 1 Valérie Fraix 1 Laurent Goetz 1 Eric Seigneuret 2 Eric Bardinet 3 Muriel Ferraye 1 Bettina Debû 1 Paul Krack 1 Jérôme Yelnik 4 Pierre Pollak 1 Alim Louis Benabid 1, 2
1 GIN - Grenoble Institut des Neurosciences
2 Pôle tête, cou et chirurgie réparatrice
3 NCIC - Neurosciences cognitives et imagerie cérébrale
4 Neurologie et thérapeutique expérimentale
Abstract : In animals, the pedunculopontine (PPN) and the sub-cuneiform (SCU) nuclei located in the upper brainstem are involved during the processing of gait. Similar functional nuclei are suspected in humans but their role in gait is unclear. Here we show that, using extra-cellular recordings of the PPN/SCU region obtained in two parkinsonian patients, the SCU neurons increased their firing rate without modifying their firing pattern during mimicked steps. We conclude that SCU neurons are activated during gait processes.
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Neuroscience, Elsevier - International Brain Research Organization, 2009, 158 (4), pp.1201-5. 〈10.1016/j.neuroscience.2008.10.046〉
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http://www.hal.inserm.fr/inserm-00536386
Contributeur : Jean-Paul Issartel <>
Soumis le : mardi 16 novembre 2010 - 10:21:03
Dernière modification le : vendredi 31 août 2018 - 08:47:30

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Brigitte Piallat, Stéphane Chabardès, Napoleon Torres, Valérie Fraix, Laurent Goetz, et al.. Gait is associated with an increase in tonic firing of the sub-cuneiform nucleus neurons.. Neuroscience, Elsevier - International Brain Research Organization, 2009, 158 (4), pp.1201-5. 〈10.1016/j.neuroscience.2008.10.046〉. 〈inserm-00536386〉

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