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Article Dans Une Revue Physical Review Letters Année : 2010

Single cells spreading on a protein lattice adopt an energy minimizing shape

Résumé

When spreading onto a protein microlattice living cells spontaneously acquire simple shapes determined by the lattice geometry. This suggests that, on a lattice, living cells' shapes are in thermodynamic metastable states. Using a model at thermodynamic equilibrium we are able to reproduce the observed shapes. We build a phase diagram based on two adimensional parameters characterizing essential cellular properties involved in spreading: the cell's compressibility and fluctuations.
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Dates et versions

inserm-00529787 , version 1 (26-10-2010)

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Benoit Vianay, Jos Käfer, Emmanuelle Planus, Marc R. Block, François Graner, et al.. Single cells spreading on a protein lattice adopt an energy minimizing shape. Physical Review Letters, 2010, 105 (12), pp.128101. ⟨10.1103/PhysRevLett.105.128101⟩. ⟨inserm-00529787⟩
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