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A minimally invasive microdevice for molecular sampling and analysis.

Marie-Line Cosnier 1 Franck Martin 1 Ali Bouamrani 2 François Berger 2 Patrice Caillat 1
1 CEA-LETI - Commissariat à l'énergie atomique et aux énergies alternatives - Laboratoire d'Electronique et de Technologie de l'Information
2 GIN - Grenoble Institut des Neurosciences
Abstract : In this paper, we present a new minimally invasive biopsy microdevice adapted to proteomic mass spectrometry analysis. The concept is born from a multidisciplinary collaboration in fields of proteomics, cancer research, and microtechnology. In mixing different skills, we have developed and manufactured a miniaturized biopsy device using microtechnology techniques in order to minimize tissue damage during surgical gesture. Dedicated chemically functionalized areas were added to the device in order to increase capture yield and specificity during tissue contact. Fields of application range from cancer research to the study of neurodegenerative diseases.
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https://www.hal.inserm.fr/inserm-00527587
Contributor : Jean-Paul Issartel <>
Submitted on : Tuesday, October 19, 2010 - 4:18:06 PM
Last modification on : Thursday, June 11, 2020 - 5:04:05 PM

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Marie-Line Cosnier, Franck Martin, Ali Bouamrani, François Berger, Patrice Caillat. A minimally invasive microdevice for molecular sampling and analysis.. IEEE Transactions on Biomedical Engineering, Institute of Electrical and Electronics Engineers, 2009, 56 (12), pp.2898-904. ⟨10.1109/TBME.2009.2026582⟩. ⟨inserm-00527587⟩

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