A minimally invasive microdevice for molecular sampling and analysis. - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Journal Articles IEEE Transactions on Biomedical Engineering Year : 2009

A minimally invasive microdevice for molecular sampling and analysis.

Abstract

In this paper, we present a new minimally invasive biopsy microdevice adapted to proteomic mass spectrometry analysis. The concept is born from a multidisciplinary collaboration in fields of proteomics, cancer research, and microtechnology. In mixing different skills, we have developed and manufactured a miniaturized biopsy device using microtechnology techniques in order to minimize tissue damage during surgical gesture. Dedicated chemically functionalized areas were added to the device in order to increase capture yield and specificity during tissue contact. Fields of application range from cancer research to the study of neurodegenerative diseases.

Domains

Bioengineering
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Dates and versions

inserm-00527587 , version 1 (19-10-2010)

Identifiers

Cite

Marie-Line Cosnier, Franck Martin, Ali Bouamrani, François R. Berger, Patrice Caillat. A minimally invasive microdevice for molecular sampling and analysis.. IEEE Transactions on Biomedical Engineering, 2009, 56 (12), pp.2898-904. ⟨10.1109/TBME.2009.2026582⟩. ⟨inserm-00527587⟩
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