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Journal articles
Targeting breast cancer stem cells: fishing season open!
Abstract : Studies describing tumor as a hierarchically-organized cell population have changed the classical oncogenesis view and proposes new therapeutic strategies. Cancer stem cells (CSC) are thought to sustain tumor initiation/maintenance, therapy resistance, and systemic metastases. Targeting this tumor cell population is crucial to achieve a true cure. A large research effort is now aiming atdeveloping drugs targeting CSCs based either on a priori understanding of key pathways regulating CSC biology or high-throughput screening to identify novel targets and compounds.
https://www.hal.inserm.fr/inserm-00526321
Contributor : Christophe Ginestier <>
Submitted on : Monday, October 3, 2011 - 2:30:51 PM
Last modification on : Thursday, December 20, 2018 - 11:19:00 AM
Long-term archiving on: : Wednesday, January 4, 2012 - 2:20:24 AM
Contributor : Christophe Ginestier <>
Submitted on : Monday, October 3, 2011 - 2:30:51 PM
Last modification on : Thursday, December 20, 2018 - 11:19:00 AM
Long-term archiving on: : Wednesday, January 4, 2012 - 2:20:24 AM
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