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Journal Articles Breast Cancer Research Year : 2010

Targeting breast cancer stem cells: fishing season open!

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Abstract

Studies describing tumor as a hierarchically-organized cell population have changed the classical oncogenesis view and proposes new therapeutic strategies. Cancer stem cells (CSC) are thought to sustain tumor initiation/maintenance, therapy resistance, and systemic metastases. Targeting this tumor cell population is crucial to achieve a true cure. A large research effort is now aiming atdeveloping drugs targeting CSCs based either on a priori understanding of key pathways regulating CSC biology or high-throughput screening to identify novel targets and compounds.
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Dates and versions

inserm-00526321 , version 1 (03-10-2011)

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  • HAL Id : inserm-00526321 , version 1
  • PUBMED : 20887639

Cite

Christophe Ginestier, Emmanuelle Charafe-Jauffret, Daniel Birnbaum. Targeting breast cancer stem cells: fishing season open!. Breast Cancer Research, 2010, 12 (5), pp.312. ⟨inserm-00526321⟩

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