Association of lung function with physical, mental and cognitive function in early old age. - Archive ouverte HAL Access content directly
Journal Articles AGE Year : 2011

Association of lung function with physical, mental and cognitive function in early old age.

(1, 2, 3) , (1) , (1) , (4) , (3) , (1) , (2) , (1)
1
2
3
4

Abstract

Lung function predicts mortality; whether it is associated with functional status in the general population remains unclear. This study examined the association of lung function with multiple measures of functioning in early old age. Data are drawn from the Whitehall II study; data on lung function (forced expiratory volume in 1 s, height FEV(1)), walking speed (2.44 m), cognitive function (memory and reasoning) and self-reported physical and mental functioning (SF-36) were available on 4,443 individuals, aged 50-74 years. In models adjusted for age, 1 standard deviation (SD) higher height-adjusted FEV(1) was associated with greater walking speed (beta=0.16, 95% CI: 0.13, 0.19), memory (beta=0.09, 95% CI: 0.06, 0.12), reasoning (beta=0.16, 95% CI: 0.13, 0.19) and self-reported physical functioning (beta=0.13, 95% CI: 0.10, 0.16). Socio-demographic measures, health behaviours (smoking, alcohol, physical activity, fruit/vegetable consumption), body mass index (BMI) and chronic conditions explained two-thirds of the association with walking speed and self-assessed physical functioning and over 80% of the association with cognitive function. Our results suggest that lung function is a good 'summary' measure of overall functioning in early old age.
Fichier principal
Vignette du fichier
inserm-00524562_edited.pdf (189.77 Ko) Télécharger le fichier
Vignette du fichier
Lung_function_and_functioning_AGE_Final_version.pdf (280.99 Ko) Télécharger le fichier
Origin : Files produced by the author(s)
Origin : Files produced by the author(s)
Loading...

Dates and versions

inserm-00524562 , version 1 (08-10-2010)

Identifiers

Cite

Archana Singh-Manoux, Aline Dugravot, Francine Kauffmann, Alexis Elbaz, Joel Ankri, et al.. Association of lung function with physical, mental and cognitive function in early old age.. AGE, 2011, 33 (3), pp.385-92. ⟨10.1007/s11357-010-9189-x⟩. ⟨inserm-00524562⟩
158 View
439 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More