Global epidemiology of hepatitis C virus infection, The Lancet Infectious Diseases, vol.5, issue.9, pp.558-567, 2005. ,
DOI : 10.1016/S1473-3099(05)70216-4
Epidemiology of hepatitis C virus infection, World Journal of Gastroenterology, vol.13, issue.17, pp.2436-2441, 2007. ,
DOI : 10.3748/wjg.v13.i17.2436
Hepatitis C Virus Infection, New England Journal of Medicine, vol.345, issue.1, pp.41-52, 2001. ,
DOI : 10.1056/NEJM200107053450107
Prospects for a vaccine against the hepatitis C virus, Nature, vol.5, issue.7053, pp.961-966, 2005. ,
DOI : 10.1056/NEJMoa051016
Peginterferon Alfa-2a plus Ribavirin for Chronic Hepatitis C Virus Infection, New England Journal of Medicine, vol.347, issue.13, pp.975-982, 2002. ,
DOI : 10.1056/NEJMoa020047
Sequence diversity of hepatitis C virus: Implications for immune control and therapy, World Journal of Gastroenterology, vol.13, issue.36, pp.4808-4817, 2007. ,
DOI : 10.3748/wjg.v13.i36.4808
Interferon-based therapy of hepatitis C, Advanced Drug Delivery Reviews, vol.59, issue.12, pp.1222-1241, 2007. ,
DOI : 10.1016/j.addr.2007.07.002
The Hepatitis C Virus Life Cycle as a Target for New Antiviral Therapies, Gastroenterology, vol.132, issue.5, pp.1979-1998, 2007. ,
DOI : 10.1053/j.gastro.2007.03.116
Novel Insights into Hepatitis C Virus Replication and Persistence, Adv.Virus Res, vol.63, pp.71-180, 2004. ,
DOI : 10.1016/S0065-3527(04)63002-8
Replication of hepatitis C virus, Nature Reviews Microbiology, vol.281, issue.6, pp.453-463, 2007. ,
DOI : 10.1038/nrmicro1645
URL : https://hal.archives-ouvertes.fr/hal-00313684
Hepatitis C viral dynamics in vivo and the antiviral efficacy of interferon-alpha therapy, pp.282-5386, 1998. ,
Rates of spontaneous mutation, pp.1667-1686, 1998. ,
Genetic diversity and evolution of hepatitis C virus - 15 years on, Journal of General Virology, vol.85, issue.11, pp.3173-3188, 2004. ,
DOI : 10.1099/vir.0.80401-0
Therapeutic control of hepatitis C virus: the role of neutralizing monoclonal antibodies, Curr.Top.Microbiol.Immunol, vol.317, pp.1-38, 2008. ,
Hepatitis C virus entry: potential receptors and their biological functions, Journal of General Virology, vol.87, issue.5, pp.1075-1084, 2006. ,
DOI : 10.1099/vir.0.81646-0
URL : https://hal.archives-ouvertes.fr/hal-00105501
Immune evasion versus recovery after acute hepatitis C virus infection from a shared source, The Journal of Experimental Medicine, vol.11, issue.11, pp.1725-1731, 2005. ,
DOI : 10.1128/JVI.75.23.11392-11400.2001
Comprehensive analyses of CD8+ T cell responses during longitudinal study of acute human hepatitis C, Hepatology, vol.38, issue.10, pp.104-112, 2005. ,
DOI : 10.1002/hep.20749
Cellular immune selection with hepatitis C virus persistence in humans, The Journal of Experimental Medicine, vol.36, issue.11, pp.1741-1752, 2005. ,
DOI : 10.1016/S0022-1759(01)00535-X
Stable Cytotoxic T Cell Escape Mutation in Hepatitis C Virus Is Linked to Maintenance of Viral Fitness, PLoS Pathogens, vol.10, issue.9, p.1000143, 2008. ,
DOI : 10.1371/journal.ppat.1000143.g007
Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line, Science, vol.285, issue.5424, pp.110-113, 1999. ,
DOI : 10.1126/science.285.5424.110
Infectious Hepatitis C Virus Pseudo-particles Containing Functional E1???E2 Envelope Protein Complexes, The Journal of Experimental Medicine, vol.72, issue.5, pp.633-642, 2003. ,
DOI : 10.1093/emboj/21.12.2893
URL : https://hal.archives-ouvertes.fr/inserm-00133783
Hepatitis C virus glycoproteins mediate pH-dependent cell entry of pseudotyped retroviral particles, Proc.Natl.Acad.Sci.U.S, pp.100-7271, 2003. ,
DOI : 10.1073/pnas.0832180100
Hepatitis C virus entry: Molecular biology and clinical implications, Hepatology, vol.7, issue.3, pp.527-535, 2006. ,
DOI : 10.1002/hep.21321
Hepatitis C Virus Entry, Journal of Biological Chemistry, vol.283, issue.7, pp.3689-3693, 2008. ,
DOI : 10.1074/jbc.R700024200
Claudin-1 is a hepatitis C virus coreceptor required for a late step in entry, Nature446, issue.7137, pp.801-805, 2007. ,
Neutralizing Host Responses in Hepatitis C Virus Infection Target Viral Entry at Postbinding Steps and Membrane Fusion, Gastroenterology, vol.135, issue.5, pp.135-1719, 2008. ,
DOI : 10.1053/j.gastro.2008.07.018
Association between Hepatitis C Virus and Very-Low-Density Lipoprotein (VLDL)/LDL Analyzed in Iodixanol Density Gradients, Journal of Virology, vol.80, issue.5, pp.2418-2428, 2006. ,
DOI : 10.1128/JVI.80.5.2418-2428.2006
An Interplay between Hypervariable Region 1 of the Hepatitis C Virus E2 Glycoprotein, the Scavenger Receptor BI, and High-Density Lipoprotein Promotes both Enhancement of Infection and Protection against Neutralizing Antibodies, Journal of Virology, vol.79, issue.13, pp.79-8217, 2005. ,
DOI : 10.1128/JVI.79.13.8217-8229.2005
URL : https://hal.archives-ouvertes.fr/hal-00313682
High Density Lipoprotein Inhibits Hepatitis C Virus-neutralizing Antibodies by Stimulating Cell Entry via Activation of the Scavenger Receptor BI, Journal of Biological Chemistry, vol.281, issue.27 ,
DOI : 10.1074/jbc.M602706200
URL : https://hal.archives-ouvertes.fr/hal-00313930
The scavenger receptor BI and its ligand, HDL: partners in crime against HCV neutralizing antibodies, Journal of Viral Hepatitis, vol.80, issue.s1, pp.68-76, 2007. ,
DOI : 10.1038/nature05654
Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81, Hepatology, vol.279, issue.6, pp.46-1722, 2007. ,
DOI : 10.1002/hep.21994
URL : https://hal.archives-ouvertes.fr/inserm-00395706
Hepatitis C Virus Envelope Glycoprotein E2 Glycans Modulate Entry, CD81 Binding, and Neutralization, Journal of Virology, vol.81, issue.15, pp.8072-8079, 2007. ,
DOI : 10.1128/JVI.00459-07
The Neutralizing Activity of Anti-Hepatitis C Virus Antibodies Is Modulated by Specific Glycans on the E2 Envelope Protein, Journal of Virology, vol.81, issue.15, pp.8101-8111, 2007. ,
DOI : 10.1128/JVI.00127-07
Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies, Hepatology, vol.7, issue.1, pp.17-24, 2008. ,
DOI : 10.1002/hep.21959
Antibody neutralization and escape by HIV-1, Nature, vol.422, issue.6929, pp.307-312, 2003. ,
DOI : 10.1038/nature01470
HIV-1 evades antibody-mediated neutralization through conformational masking of receptorbinding sites, pp.420-678, 2002. ,
Broadly neutralizing antibodies protect against hepatitis C virus quasispecies challenge, Nature Medicine, vol.78, issue.1, pp.25-27, 2008. ,
DOI : 10.1016/j.virol.2006.05.015
Adaptive immune responses in acute and chronic hepatitis C virus infection, Nature, vol.38, issue.7053, pp.946-952, 2005. ,
DOI : 10.1128/JVI.78.3.1575-1581.2004
Analysis of Successful Immune Responses in Persons Infected with Hepatitis C Virus, The Journal of Experimental Medicine, vol.69, issue.9, pp.1499-1512, 2000. ,
DOI : 10.1073/pnas.92.7.2755
Determinants of Viral Clearance and Persistence during Acute Hepatitis C Virus Infection, The Journal of Experimental Medicine, vol.43, issue.10, pp.1395-1406, 2001. ,
DOI : 10.1126/science.284.5415.825
Viral and immunological determinants of hepatitis C virus clearance, persistence, and disease, Proc.Natl.Acad.Sci.U.S.A99(24), pp.15661-15668, 2002. ,
DOI : 10.1073/pnas.202608299
Impaired Effector Function of Hepatitis C Virus-Specific CD8+ T Cells in Chronic Hepatitis C Virus Infection, The Journal of Immunology, vol.169, issue.6, pp.3447-3458, 2002. ,
DOI : 10.4049/jimmunol.169.6.3447
Intrahepatic Genetic Inoculation of Hepatitis C Virus RNA Confers Cross-Protective Immunity, Journal of Virology, vol.75, issue.15, pp.75-7142, 2001. ,
DOI : 10.1128/JVI.75.15.7142-7148.2001
Protective immune response to hepatitis C virus in chimpanzees rechallenged following clearance of primary infection, Hepatology, vol.33, issue.6, pp.1479-1487, 2001. ,
DOI : 10.1053/jhep.2001.24371
Previously Infected and Recovered Chimpanzees Exhibit Rapid Responses That Control Hepatitis C Virus Replication upon Rechallenge, Journal of Virology, vol.76, issue.13, pp.6586-6595, 2002. ,
DOI : 10.1128/JVI.76.13.6586-6595.2002
T Cells Are Required for Protection from Persistent Hepatitis C Virus Infection, The Journal of Experimental Medicine, vol.2, issue.12, pp.1645-1655, 2003. ,
DOI : 10.1038/nri779
Kinetics of CD4+ and CD8+ Memory T-Cell Responses during Hepatitis C Virus Rechallenge of Previously Recovered Chimpanzees, Journal of Virology, vol.77, issue.8, pp.4781-4793, 2003. ,
DOI : 10.1128/JVI.77.8.4781-4793.2003
HCV Persistence and Immune Evasion in the Absence of Memory T Cell Help, Science, vol.302, issue.5645, pp.302-659, 2003. ,
DOI : 10.1126/science.1088774
Cross-Genotype Immunity to Hepatitis C Virus, Journal of Virology, vol.78, issue.3, pp.1575-1581, 2004. ,
DOI : 10.1128/JVI.78.3.1575-1581.2004
Previously Infected Chimpanzees Are Not Consistently Protected against Reinfection or Persistent Infection after Reexposure to the Identical Hepatitis C Virus Strain, Journal of Virology, vol.82, issue.16, pp.8183-8195, 2008. ,
DOI : 10.1128/JVI.00142-08
A target on the move: Innate and adaptive immune escape strategies of hepatitis C virus, Antiviral Research, vol.69, issue.3, pp.129-141, 2006. ,
DOI : 10.1016/j.antiviral.2005.12.001
Outcome of acute hepatitis C is related to virus-specific CD4 function and maturation of antiviral memory CD8 responses, Hepatology, vol.79, issue.1, pp.126-139, 2006. ,
DOI : 10.1002/hep.21242
Discordant role of CD4 T-cell response relative to neutralizing antibody and CD8 Tcell responses in acute hepatitis C, pp.132-654, 2007. ,
Immunological significance of cytotoxic T lymphocyte epitope variants in patients chronically infected by the hepatitis C virus., Journal of Clinical Investigation, vol.100, issue.9, pp.2376-2385, 1997. ,
DOI : 10.1172/JCI119778
Persistent hepatitis C virus infection in a chimpanzee is associated with emergence of a cytotoxic T lymphocyte escape variant., Proc.Natl.Acad.Sci.U.S, pp.92-2755, 1995. ,
DOI : 10.1073/pnas.92.7.2755
The Outcome of Hepatitis C Virus Infection Is Predicted by Escape Mutations in Epitopes Targeted by Cytotoxic T Lymphocytes, Immunity, vol.15, issue.6, pp.883-895, 2001. ,
DOI : 10.1016/S1074-7613(01)00245-X
CD8 Epitope Escape and Reversion in Acute HCV Infection, The Journal of Experimental Medicine, vol.67, issue.12, pp.200-1593, 2004. ,
DOI : 10.1128/JVI.75.12.5550-5558.2001
Divergent and convergent evolution after a common-source outbreak of hepatitis C virus, The Journal of Experimental Medicine, vol.73, issue.11, pp.1753-1759, 2005. ,
DOI : 10.1046/j.1365-2249.2002.01840.x
Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution, Hepatology, vol.35, issue.3, pp.43-563, 2006. ,
DOI : 10.1002/hep.21049
Virus-Specific CD8+ Lymphocytes Share the Same Effector-Memory Phenotype but Exhibit Functional Differences in Acute Hepatitis B and C, Journal of Virology, vol.76, issue.24, pp.12423-12434, 2002. ,
DOI : 10.1128/JVI.76.24.12423-12434.2002
Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection, Hepatology, vol.79, issue.4, pp.828-837, 2005. ,
DOI : 10.1002/hep.20856
Suppression of HCV-specific T cells without differential hierarchy demonstrated ex vivo in persistent HCV infection, Hepatology, vol.38, issue.6, pp.38-1437, 2003. ,
DOI : 10.1053/jhep.2003.09026
An immunomodulatory role for CD4+CD25+ regulatory T lymphocytes in hepatitis C virus infection, Hepatology, vol.3, issue.5, pp.1062-1071, 2004. ,
DOI : 10.1002/hep.20454
T Cells with a CD4+CD25+ Regulatory Phenotype Suppress In Vitro Proliferation of Virus-Specific CD8+ T Cells during Chronic Hepatitis C Virus Infection, Journal of Virology, vol.79, issue.12, pp.7860-7867, 2005. ,
DOI : 10.1128/JVI.79.12.7860-7867.2005
Regulatory T Cells Suppress In Vitro Proliferation of Virus-Specific CD8+ T Cells during Persistent Hepatitis C Virus Infection, Journal of Virology, vol.79, issue.12, pp.7852-7859, 2005. ,
DOI : 10.1128/JVI.79.12.7852-7859.2005
Foxp3+CD4+CD25+ T cells control virus-specific memory T cells in chimpanzees that recovered from hepatitis C, Blood, vol.107, issue.11, pp.4424-4432, 2006. ,
DOI : 10.1182/blood-2005-09-3903
Restoring function in exhausted CD8 T cells during chronic viral infection, Nature, vol.111, issue.7077, pp.682-687, 2006. ,
DOI : 10.1038/nature04444
PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression, Nature, vol.170, issue.7109, pp.443-350, 2006. ,
DOI : 10.1126/science.274.5284.94
PD-1 expression in acute hepatitis C virus (HCV) infection is associated with HCVspecific CD8 exhaustion, J Virol80, issue.22, pp.11398-11403, 2006. ,
Liver-Infiltrating Lymphocytes in Chronic Human Hepatitis C Virus Infection Display an Exhausted Phenotype with High Levels of PD-1 and Low Levels of CD127 Expression, Journal of Virology, vol.81, issue.6, pp.81-2545, 2007. ,
DOI : 10.1128/JVI.02021-06
Variable Patterns of Programmed Death-1 Expression on Fully Functional Memory T Cells after Spontaneous Resolution of Hepatitis C Virus Infection, Journal of Virology, vol.82, issue.10, pp.82-5109, 2008. ,
DOI : 10.1128/JVI.00060-08
The challenge of developing a vaccine against hepatitis C virus, Journal of Hepatology, vol.37, issue.5, pp.684-695, 2002. ,
DOI : 10.1016/S0168-8278(02)00308-2
Immunotherapy for HCV infection: next steps, Expert Review of Vaccines, vol.7, issue.7, pp.915-923, 2008. ,
DOI : 10.1586/14760584.7.7.915
Vaccines and immunotherapies against hepatitis B and hepatitis C viruses, Journal of Viral Hepatitis, vol.23, issue.45, pp.97-103, 2007. ,
DOI : 10.1002/hep.20839
Hepatitis C vaccines: Inducing and challenging memory T cells, Hepatology, vol.187, issue.6, pp.1395-1398, 2006. ,
DOI : 10.1002/hep.21210
Efficient trans-Encapsidation of Hepatitis C Virus RNAs into Infectious Virus-Like Particles, Journal of Virology, vol.82, issue.14, pp.7034-7046, 2008. ,
DOI : 10.1128/JVI.00118-08
Vaccination of chimpanzees against infection by the hepatitis C virus., Proc.Natl.Acad.Sci.U.S.A91, pp.1294-1298, 1994. ,
DOI : 10.1073/pnas.91.4.1294
Immunization of chimpanzees with an envelope protein-based vaccine enhances specific humoral and cellular immune responses that delay hepatitis C virus infection, Vaccine, vol.22, issue.8, pp.22-991, 2004. ,
DOI : 10.1016/j.vaccine.2003.09.010
Vaccination of Chimpanzees With Plasmid DNA Encoding the Hepatitis C Virus(HCV) Envelope E2 Protein Modified the Infection After Challenge With Homologous Monoclonal HCV, Hepatology, vol.28, issue.3, pp.32-618, 2000. ,
DOI : 10.1053/jhep.2000.9877
Sustained E2 antibody response correlates with reduced peak viremia after hepatitis C virus infection in the chimpanzee, Hepatology, vol.74, issue.6, pp.1429-1436, 2005. ,
DOI : 10.1002/hep.20934
A T-cell HCV vaccine eliciting effective immunity against heterologous virus challenge in chimpanzees, Nature Medicine, vol.35, issue.2, pp.12-190, 2006. ,
DOI : 10.1038/nm1353
The Los Alamos hepatitis C sequence database, Bioinformatics, vol.21, issue.3, pp.379-384, 2005. ,
DOI : 10.1093/bioinformatics/bth485
Hepatitis C virus structural proteins assemble into viruslike particles in insect cells, J.Virol, vol.72, issue.5, pp.3827-3836, 1998. ,
Hepatitis C virus-like particles synthesized in insect cells as a potential vaccine candidate, Gastroenterology, vol.117, issue.6, pp.1397-1407, 1999. ,
DOI : 10.1016/S0016-5085(99)70290-8
Binding of Hepatitis C Virus-Like Particles Derived from Infectious Clone H77C to Defined Human Cell Lines, Journal of Virology, vol.76, issue.3, pp.1181-1193, 2002. ,
DOI : 10.1128/JVI.76.3.1181-1193.2002
Cellular Binding of Hepatitis C Virus Envelope Glycoprotein E2 Requires Cell Surface Heparan Sulfate, Journal of Biological Chemistry, vol.278, issue.42, pp.278-41003, 2003. ,
DOI : 10.1074/jbc.M302267200
Scavenger Receptor Class B Type I and Hepatitis C Virus Infection of Primary Tupaia Hepatocytes, Journal of Virology, vol.79, issue.9, pp.5774-5785, 2005. ,
DOI : 10.1128/JVI.79.9.5774-5785.2005
Uptake and presentation of hepatitis C virus-like particles by human dendritic cells, Blood, vol.105, issue.9, pp.105-3605, 2005. ,
DOI : 10.1182/blood-2004-05-1952
Scavenger Receptor Class B Is Required for Hepatitis C Virus Uptake and Cross-Presentation by Human Dendritic Cells, Journal of Virology, vol.82, issue.7, pp.82-3466, 2008. ,
DOI : 10.1128/JVI.02478-07
Hepatitis C virus???like particles induce virus-specific humoral and cellular immune responses in mice, Hepatology, vol.34, issue.2, pp.417-423, 2001. ,
DOI : 10.1053/jhep.2001.26523
Immunization with hepatitis C virus-like particles protects mice from recombinant hepatitis C virusvaccinia infection, Proc.Natl.Acad.Sci.U.S.A100, pp.6753-6758, 2003. ,
Hepatitis C virus???like particles combined with novel adjuvant systems enhance virus-specific immune responses, Hepatology, vol.10, issue.1, pp.52-59, 2003. ,
DOI : 10.1053/jhep.2003.50000
Immunization with hepatitis C virus-like particles results in control of hepatitis C virus infection in chimpanzees, Proc.Natl.Acad.Sci.U.S, pp.104-8427, 2007. ,
DOI : 10.1073/pnas.0702162104
Vaccine-induced early control of hepatitis C virus infection in chimpanzees fails to impact on hepatic PD-1 and chronicity, Hepatology, vol.201, issue.3, pp.45-602, 2007. ,
DOI : 10.1002/hep.21573
Ido expression by dendritic cells: tolerance and tryptophan catabolism, Nature Reviews Immunology, vol.467, issue.10, pp.762-774, 2004. ,
DOI : 10.1016/S0041-1345(00)02792-5
Evidence for Protection against Chronic Hepatitis C Virus Infection in Chimpanzees by Immunization with Replicating Recombinant Vaccinia Virus, Journal of Virology, vol.82, issue.21, pp.10896-10905, 2008. ,
DOI : 10.1128/JVI.01179-08
Hepatitis C vaccine: supply and demand, The Lancet Infectious Diseases, vol.8, issue.6, pp.379-386, 2008. ,
DOI : 10.1016/S1473-3099(08)70126-9
The changing epidemiology of hepatitis C virus infection in Europe, Journal of Hepatology, vol.48, issue.1, pp.148-162, 2008. ,
DOI : 10.1016/j.jhep.2007.07.033
HCV/ HIV co-infection: time to re-evaluate the role of HIV in the liver?, Journal of Viral Hepatitis, vol.18, issue.5, pp.323-330, 2008. ,
DOI : 10.1128/JVI.01890-06
Incidence of Hepatitis C in Patients Receiving Different Preparations of Hepatitis B Immunoglobulins after Liver Transplantation, Annals of Internal Medicine, vol.128, issue.10, pp.810-816, 1998. ,
DOI : 10.7326/0003-4819-128-10-199805150-00003
Neutralizing antibody response during acute and chronic hepatitis C virus infection, Proc.Natl.Acad.Sci.U.S.A101, pp.10149-10154, 2004. ,
DOI : 10.1073/pnas.0403519101
Evidence for cross-genotype neutralization of hepatitis C virus pseudo-particles and enhancement of infectivity by apolipoprotein C1, Proc.Natl.Acad.Sci.U.S, pp.102-4560, 2005. ,
DOI : 10.1073/pnas.0501275102
Hepatitis C immune globulin to prevent HCV recurrence after liver transplantation: Chasing windmills?, Liver Transplantation, vol.80, issue.9, pp.1317-1319, 2006. ,
DOI : 10.1002/lt.20889
A candidate vaccine based on the hepatitis C E1 protein: tolerability and immunogenicity in healthy volunteers, Vaccine, vol.22, issue.23-24, pp.22-23, 2004. ,
DOI : 10.1016/j.vaccine.2004.02.002
A pilot study of therapeutic vaccination with envelope protein E1 in 35 patients with chronic hepatitis C, Hepatology, vol.31, issue.5, pp.38-1289, 2003. ,
DOI : 10.1053/jhep.2003.50474
Therapeutic Vaccination of Chronic Hepatitis C Nonresponder Patients With the Peptide Vaccine IC41, Gastroenterology, vol.134, issue.5, pp.134-1385, 2008. ,
DOI : 10.1053/j.gastro.2008.02.058
Immunogenicity and safety of a novel therapeutic hepatitis C virus (HCV) peptide vaccine: A randomized, placebo controlled trial for dose optimization in 128 healthy subjects, Vaccine, vol.24, issue.20, pp.24-4343, 2006. ,
DOI : 10.1016/j.vaccine.2006.03.009
Phase I clinical study of a personalized peptide vaccination for patients infected with hepatitis C virus (HCV) 1b who failed to respond to interferonbased therapy, pp.25-7429, 2007. ,