A. Aiba, M. Kano, C. Chen, M. Stanton, G. Fox et al., Deficient cerebellar long-term depression and impaired motor learning in mGluR1 mutant mice, Cell, vol.79, pp.377-388, 1994.

A. Batchelor, D. Madge, and J. Garthwaite, Synaptic activation of metabotropic glutamate receptors in the parallel Fibre-Purkinje cell pathway in rat cerebellar slices, Neuroscience, vol.63, issue.4, pp.911-915, 1994.
DOI : 10.1016/0306-4522(94)90558-4

A. Baude, Z. Nusser, J. Roberts, E. Mulvihill, R. Mcilhinney et al., The metabotropic glutamate receptor (mGluRl??) is concentrated at perisynaptic membrane of neuronal subpopulations as detected by immunogold reaction, Neuron, vol.11, issue.4, pp.771-787, 1993.
DOI : 10.1016/0896-6273(93)90086-7

A. Benians, M. Nobles, S. Hosny, and A. Tinker, Regulators of G-protein Signaling Form a Quaternary Complex with the Agonist, Receptor, and G-protein: A NOVEL EXPLANATION FOR THE ACCELERATION OF SIGNALING ACTIVATION KINETICS, Journal of Biological Chemistry, vol.280, issue.14, pp.13383-13394, 2005.
DOI : 10.1074/jbc.M410163200

I. Bezprozvanny, J. Watras, and B. Ehrlich, Bell-shaped calcium-response curves of lns(l,4,5)P3- and calcium-gated channels from endoplasmic reticulum of cerebellum, Nature, vol.351, issue.6329, pp.751-754, 1991.
DOI : 10.1038/351751a0

S. Brenowitz and W. Regehr, Associative Short-Term Synaptic Plasticity Mediated by Endocannabinoids, Neuron, vol.45, issue.3, pp.419-431, 2005.
DOI : 10.1016/j.neuron.2004.12.045

M. Canepari, C. Auger, and D. Ogden, Ca2+ Ion Permeability and Single-Channel Properties of the Metabotropic Slow EPSC of Rat Purkinje Neurons, Journal of Neuroscience, vol.24, issue.14, pp.3563-3573, 2004.
DOI : 10.1523/JNEUROSCI.5374-03.2004

M. Canepari, L. Nelson, G. Papageorgiou, J. Corrie, and D. Ogden, Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmitters, Journal of Neuroscience Methods, vol.112, issue.1, pp.29-42, 2001.
DOI : 10.1016/S0165-0270(01)00451-4

M. Canepari and D. Ogden, Evidence for protein tyrosine phosphatase, tyrosine kinase, and G-protein regulation of the parallel fiber metabotropic slow EPSC of rat cerebellar Purkinje neurons, J Neurosci, vol.23, pp.4066-4071, 2003.

M. Canepari, G. Papageorgiou, J. Corrie, C. Watkins, and D. Ogden, The conductance underlying the parallel fibre slow EPSP in rat cerebellar Purkinje neurones studied with photolytic release of L-glutamate, The Journal of Physiology, vol.2, issue.3, pp.765-772, 2001.
DOI : 10.1111/j.1469-7793.2001.00765.x

M. Casado, S. Dieudonne, and P. Ascher, Presynaptic N-methyl-D-aspartate receptors at the parallel fiber-Purkinje cell synapse, Proceedings of the National Academy of Sciences, vol.97, issue.21, pp.11593-11597, 2000.
DOI : 10.1073/pnas.200354297

M. Casado, P. Isope, and P. Ascher, Involvement of Presynaptic N-Methyl-D-Aspartate Receptors in Cerebellar Long-Term Depression, Neuron, vol.33, issue.1, pp.123-130, 2002.
DOI : 10.1016/S0896-6273(01)00568-2

C. Chen and R. Thompson, Temporal specificity of long-term depression in parallel fiber--Purkinje synapses in rat cerebellar slice., Learning & Memory, vol.2, issue.3-4, pp.185-198, 1995.
DOI : 10.1101/lm.2.3-4.185

L. Cingolani, M. Gymnopoulos, A. Boccaccio, M. Stocker, and P. Pedarzani, Developmental regulation of smallconductance Ca 2+ -activated K + channel expression and function in rat Purkinje neurons, J Neurosci, vol.22, pp.4456-4467, 2002.

M. Coesmans, P. Smitt, D. Linden, R. Shigemoto, T. Hirano et al., Mechanisms underlying cerebellar motor deficits due to mGluR1-autoantibodies, Annals of Neurology, vol.106, issue.3, pp.325-336, 2003.
DOI : 10.1002/ana.10451

F. Conquet, Z. Bashir, C. Davies, H. Daniel, F. Ferraguti et al., Motor deficit and impairment of synaptic plasticity in mice lacking mGluR1, Nature, vol.372, issue.6503, pp.237-243, 1994.
DOI : 10.1038/372237a0

H. Cruzblanca, D. Koh, and B. Hille, Bradykinin inhibits M current via phospholipase C and Ca 2+ release from IP3-sensitive Ca 2+ stores in rat sympathetic neurons, Proc Natl Acad Sci, pp.7151-7156, 1998.

H. Daniel, C. Levenes, L. Fagni, F. Conquet, J. Bockaert et al., Inositol-1,4,5-trisphosphate-mediated rescue of cerebellar long-term depression in subtype 1 metabotropic glutamate receptor mutant mouse, Neuroscience, vol.92, issue.1, pp.1-6, 1999.
DOI : 10.1016/S0306-4522(99)00136-0

D. Zeeuw, C. Hansel, C. Bian, F. Koekkoek, S. Van-alphen et al., Expression of a Protein Kinase C Inhibitor in Purkinje Cells Blocks Cerebellar LTD and Adaptation of the Vestibulo-Ocular Reflex, Neuron, vol.20, issue.3, pp.495-508, 1998.
DOI : 10.1016/S0896-6273(00)80990-3

D. Digregorio and J. Vergara, neuromuscular junction, The Journal of Physiology, vol.83, issue.3, pp.585-592, 1997.
DOI : 10.1111/j.1469-7793.1997.585ba.x

P. Doroshenko, A. Woppmann, G. Miljanich, and G. Augustine, Pharmacologically Distinct Presynaptic Calcium Channels in Cerebellar Excitatory and Inhibitory Synapses, Neuropharmacology, vol.36, issue.6, pp.865-872, 1997.
DOI : 10.1016/S0028-3908(97)00032-4

J. Edgerton and P. Reinhart, Distinct contributions of small and large conductance Ca2+-activated K+ channels to rat Purkinje neuron function, The Journal of Physiology, vol.548, issue.1, pp.53-69, 2003.
DOI : 10.1113/jphysiol.2002.027854

L. Fierro and I. Llano, High endogenous calcium buffering in Purkinje cells from rat cerebellar slices., The Journal of Physiology, vol.496, issue.3, pp.617-625, 1996.
DOI : 10.1113/jphysiol.1996.sp021713

E. Finch and G. Augustine, Local calcium signalling by inositol-1,4,5-trisphosphate in Purkinje cell dendrites, Nature, vol.396, pp.753-756, 1998.

E. Finch, T. Turner, and S. Goldin, Calcium as a coagonist of inositol 1,4,5-trisphosphate-induced calcium release, Science, vol.252, issue.5004, pp.443-446, 1991.
DOI : 10.1126/science.2017683

A. Fujiwara, K. Hirose, T. Yamazawa, and M. Iino, Reduced IP3 sensitivity of IP3 receptor in Purkinje neurons, Neuroreport, vol.12, issue.12, pp.2647-2651, 2001.
DOI : 10.1097/00001756-200108280-00012

M. Galante and M. Diana, Group I Metabotropic Glutamate Receptors Inhibit GABA Release at Interneuron-Purkinje Cell Synapses through Endocannabinoid Production, Journal of Neuroscience, vol.24, issue.20, pp.4865-4874, 2004.
DOI : 10.1523/JNEUROSCI.0403-04.2004

J. Haley, F. Abogadie, J. Fernandez-fernandez, M. Dayrell, Y. Vallis et al., Bradykinin, but not muscarinic, inhibition of M-current in rat sympathetic ganglion neurons involves phospholipase C-beta 4, J Neurosci, vol.20, p.105, 2000.

N. Hartell, Receptors, second messengers and protein kinases required for heterosynaptic cerebellar long-term depression, Neuropharmacology, vol.40, issue.1, pp.148-161, 2001.
DOI : 10.1016/S0028-3908(00)00107-6

J. Hartmann, R. Blum, Y. Kovalchuk, H. Adelsberger, R. Kuner et al., Distinct Roles of G??q and G??11 for Purkinje Cell Signaling and Motor Behavior, Journal of Neuroscience, vol.24, issue.22, pp.5119-5130, 2004.
DOI : 10.1523/JNEUROSCI.4193-03.2004

L. Horowitz, W. Hirdes, B. Suh, D. Hilgemann, K. Mackie et al., Phospholipase C in Living Cells, The Journal of General Physiology, vol.63, issue.3, pp.243-262, 2005.
DOI : 10.1073/pnas.111447798

T. Ichise, M. Kano, K. Hashimoto, D. Yanagihara, K. Nakao et al., mGluR1 in Cerebellar Purkinje Cells Essential for Long-Term Depression, Synapse Elimination, and Motor Coordination, Science, vol.288, issue.5472, pp.1832-1835, 2000.
DOI : 10.1126/science.288.5472.1832

D. Ireland, D. Guevremont, J. Williams, and W. Abraham, Metabotropic Glutamate Receptor-Mediated Depression of the Slow Afterhyperpolarization Is Gated by Tyrosine Phosphatases in Hippocampal CA1 Pyramidal Neurons, Journal of Neurophysiology, vol.92, issue.5, pp.2811-2819, 2004.
DOI : 10.1152/jn.01236.2003

K. Khodakhah and C. Armstrong, Induction of longterm depression and rebound potentiation by inositol trisphosphate in cerebellar Purkinje neurons, Proc Natl Acad Sci, pp.14009-14014, 1997.

K. Khodakhah and D. Ogden, Functional heterogeneity of calcium release by inositol trisphosphate in single Purkinje neurones, cultured cerebellar astrocytes, and peripheral tissues., Proceedings of the National Academy of Sciences, vol.90, issue.11, pp.4976-4980, 1993.
DOI : 10.1073/pnas.90.11.4976

K. Khodakhah and D. Ogden, Fast activation and inactivation of inositol trisphosphate-evoked Ca2+ release in rat cerebellar Purkinje neurones., The Journal of Physiology, vol.487, issue.2, pp.343-358, 1995.
DOI : 10.1113/jphysiol.1995.sp020884

S. Kim, Y. Kim, J. Yuan, R. Petralia, P. Worley et al., Activation of the TRPC1 cation channel by metabotropic glutamate receptor mGluR1, Nature, vol.426, issue.6964, pp.285-291, 2003.
DOI : 10.1038/nature02162

Y. Kishimoto, R. Fujimichi, K. Araishi, S. Kawahara, M. Kano et al., mGluR1 in cerebellar Purkinje cells is required for normal association of temporally contiguous stimuli in classical conditioning, European Journal of Neuroscience, vol.99, issue.12, pp.2416-2424, 2002.
DOI : 10.1046/j.1460-9568.2002.02407.x

T. Kosaka, K. Kosaka, T. Nakayama, W. Hunziker, and C. Heizmann, Axons and axon terminals of cerebellar Purkinje cells and basket cells have higher levels of parvalbumin immunoreactivity than somata and dendrites: quantitative analysis by immunogold labeling, Experimental Brain Research, vol.93, issue.3, pp.483-491, 1993.
DOI : 10.1007/BF00229363

T. Launey, S. Endo, R. Sakai, J. Harano, and M. Ito, Protein phosphatase 2A inhibition induces cerebellar long-term depression and declustering of synaptic AMPA receptor, Proceedings of the National Academy of Sciences, vol.101, issue.2, pp.676-681, 2004.
DOI : 10.1073/pnas.0302914101

D. Linden and J. Connor, Participation of postsynaptic PKC in cerebellar long-term depression in culture, Science, vol.254, issue.5038, pp.1656-1659, 1991.
DOI : 10.1126/science.1721243

Y. Loewenstein, S. Mahon, P. Chadderton, K. Kitamura, H. Sompolinsky et al., Bistability of cerebellar Purkinje cells modulated by sensory stimulation, Nature Neuroscience, vol.19, issue.2, pp.202-211, 2005.
DOI : 10.1007/s00424-002-0831-z

M. Mauk, K. Garcia, J. Medina, and P. Steele, Does Cerebellar LTD Mediate Motor Learning? Toward a Resolution without a Smoking Gun, Neuron, vol.20, issue.3, pp.359-362, 1998.
DOI : 10.1016/S0896-6273(00)80978-2

M. Nakamura, K. Sato, M. Fukaya, K. Araishi, A. Aiba et al., Signalling complex formation of phospholipase C?4 with metabotropic glutamate receptor 1? and inositol 1,4,5-trisphosphate receptor at the perisynapse and endoplasmic reticulum in mouse brain, 2004.

T. Nakamura, J. Barbara, K. Nakamura, and W. Ross, Synergistic Release of Ca2+ from IP3-Sensitive Stores Evoked by Synaptic Activation of mGluRs Paired with Backpropagating Action Potentials, Neuron, vol.24, issue.3, pp.727-737, 1999.
DOI : 10.1016/S0896-6273(00)81125-3

R. Napper and R. Harvey, Quantitative study of the Purkinje cell dendritic spines in the rat cerebellum, The Journal of Comparative Neurology, vol.6, issue.2, pp.158-167, 1988.
DOI : 10.1002/cne.902740203

D. Ogden, Intracellular calcium release in central neurones, Seminars in the Neurosciences, pp.281-291, 1996.
DOI : 10.1006/smns.1996.0035

D. Ogden and T. Capiod, in Single Guinea Pig Hepatocytes and Rat Purkinje Neurons, The Journal of General Physiology, vol.70, issue.6, pp.741-756, 1997.
DOI : 10.1113/jphysiol.1993.sp019813

Y. Okubo, S. Kakizawa, K. Hirose, and M. Iino, Cross Talk between Metabotropic and Ionotropic Glutamate Receptor-Mediated Signaling in Parallel Fiber-Induced Inositol 1,4,5-Trisphosphate Production in Cerebellar Purkinje Cells, Journal of Neuroscience, vol.24, issue.43, pp.9513-9520, 2004.
DOI : 10.1523/JNEUROSCI.1829-04.2004

B. Posner, R. Faure, J. Burgess, A. Bevan, D. Lachance et al., Peroxovanadium compounds. A new class of potent phosphotyrosine phosphatase inhibitors which are insulin mimetics, J Biol Chem, vol.269, pp.4596-4604, 1994.

J. Power and P. Sah, Intracellular calcium store filling by an L-type calcium current in the basolateral amygdala at subthreshold membrane potentials, The Journal of Physiology, vol.49, issue.2, pp.439-453, 2005.
DOI : 10.1113/jphysiol.2004.076711

H. Schmidt, K. Stiefel, P. Racay, B. Schwaller, and J. Eilers, Mutational analysis of dendritic Ca2+ kinetics in rodent Purkinje cells: role of parvalbumin and calbindin D28k, The Journal of Physiology, vol.551, issue.1, pp.13-32, 2003.
DOI : 10.1113/jphysiol.2002.035824

K. Scott and C. Zuker, Assembly of the Drosophila phototransduction cascade into a signalling complex shapes elementary responses, Nature, vol.395, pp.805-808, 1998.

P. Sillevis-smitt, A. Kinoshita, D. Leeuw, B. Moll, W. Coesmans et al., Paraneoplastic Cerebellar Ataxia Due to Autoantibodies against a Glutamate Receptor, New England Journal of Medicine, vol.342, issue.1, pp.21-27, 2000.
DOI : 10.1056/NEJM200001063420104

G. Stuart and M. Hausser, Initiation and spread of sodium action potentials in cerebellar purkinje cells, Neuron, vol.13, issue.3, pp.703-712, 1994.
DOI : 10.1016/0896-6273(94)90037-X

H. Takechi, J. Eilers, and A. Konnerth, A new class of synaptic response involving calcium release in dendritic spines, Nature, vol.396, pp.757-760, 1998.

H. Umemori, T. Hayashi, T. Inoue, S. Nakanishi, K. Mikoshiba et al., Involvement of protein tyrosine phosphatases in activation of the trimeric G protein Gq/11, Oncogene, vol.18, issue.51, pp.7399-7402, 1999.
DOI : 10.1038/sj.onc.1203152

S. Wang, W. Denk, and M. Häusser, Coincidence detection in single dendritic spines mediated by calcium release, Nat Neurosci, vol.3, pp.1266-1273, 2000.

M. Womack and K. Khodakhah, channels in cerebellar Purkinje neurons, European Journal of Neuroscience, vol.115, issue.7, pp.1214-1222, 2002.
DOI : 10.1046/j.1460-9568.2002.02171.x

M. Womack and K. Khodakhah, Active contribution of dendrites to the tonic and trimodal patterns of activity in cerebellar Purkinje neurons, J Neurosci, vol.22, pp.10603-10612, 2002.