Cycling through metabolism. - Archive ouverte HAL Access content directly
Journal Articles EMBO Molecular Medicine Year : 2010

Cycling through metabolism.

(1) , (1)
1

Abstract

Since the discovery of cyclins, the role of cell cycle regulators in the control of cell proliferation has been extensively studied. It is clear that proliferation requires an adapted metabolic response of the cells; hence the regulation of cell cycle must be linked to metabolic control. While at a much slower pace, the impact that the activities of cell cycle regulators such as cyclins, cyclin dependent kinases or E2F factor, transcription factor have on cell metabolism are also being uncovered. Here we will focus on recent data implicating cell cycle regulators in metabolic control, with particular attention to studies performed using mouse models. Furthermore, we will discuss the possible relevance of these findings in the context of metabolic disorders such as obesity or diabetes.
Fichier principal
Vignette du fichier
300_2_merged_1277900915.pdf (1.06 Mo) Télécharger le fichier
Origin : Files produced by the author(s)
Loading...

Dates and versions

inserm-00511802 , version 1 (26-02-2011)

Identifiers

Cite

Victor Aguilar, Lluis Fajas. Cycling through metabolism.: cell cycle and metabolism. EMBO Molecular Medicine, 2010, 2 (9), pp.338-48. ⟨10.1002/emmm.201000089⟩. ⟨inserm-00511802⟩
144 View
303 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More