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Journal Articles Chirurgie de la Main Year : 2010

[Fingertip reconstruction with occlusive dressing: Clinical results and biological analysis of the dressing content's.]

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Abstract

OBJECTIVES: To evaluate the fingertip reconstruction with occlusive dressing and explore the mechanisms and the mediators of this "fingertip regeneration". PATIENT AND METHODS: Nineteen patients who sustained a fingertip injury were treated with occlusive dressing. Two prospective studies: a clinical analysis of the aesthetics and the functional results, a biologic analysis of the dressings in order to search microorganisms, cytokines, and growth factors. RESULTS: Among 15 patients reviewed, the healing was acquired in 2.7 weeks (2.5). The thickness of the fingertip was excellent in 30% and good in 70%. The Weber test was 3.8mm for the fingertip reconstruction against 3mm for the opposite side. The analysis of the dressing exudates brings to light a pullulement of saprophyte bacterium of the skin but also pathologic species, and presence of angiogenic factors (PDGF, VEGF, EGF). CONCLUSIONS: The occlusive dressings remain a reliable and reproducible alternative for treatment of fingertip injuries in zone 1 and 2. This reconstruction seems to depend on bacterium pullulement and cellular growth factors liberation.
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inserm-00508049 , version 1 (02-08-2010)

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Guillaume Lasserre, S. Bakkouch, Julien Pauchot, Delphine Binda, S. Robin, et al.. [Fingertip reconstruction with occlusive dressing: Clinical results and biological analysis of the dressing content's.]. Chirurgie de la Main, 2010, epub ahead of print. ⟨10.1016/j.main.2010.03.011⟩. ⟨inserm-00508049⟩

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