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[Fingertip reconstruction with occlusive dressing: Clinical results and biological analysis of the dressing content's.]

Abstract : OBJECTIVES: To evaluate the fingertip reconstruction with occlusive dressing and explore the mechanisms and the mediators of this "fingertip regeneration". PATIENT AND METHODS: Nineteen patients who sustained a fingertip injury were treated with occlusive dressing. Two prospective studies: a clinical analysis of the aesthetics and the functional results, a biologic analysis of the dressings in order to search microorganisms, cytokines, and growth factors. RESULTS: Among 15 patients reviewed, the healing was acquired in 2.7 weeks (2.5). The thickness of the fingertip was excellent in 30% and good in 70%. The Weber test was 3.8mm for the fingertip reconstruction against 3mm for the opposite side. The analysis of the dressing exudates brings to light a pullulement of saprophyte bacterium of the skin but also pathologic species, and presence of angiogenic factors (PDGF, VEGF, EGF). CONCLUSIONS: The occlusive dressings remain a reliable and reproducible alternative for treatment of fingertip injuries in zone 1 and 2. This reconstruction seems to depend on bacterium pullulement and cellular growth factors liberation.
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https://www.hal.inserm.fr/inserm-00508049
Contributor : Philippe Saas <>
Submitted on : Monday, August 2, 2010 - 3:03:09 PM
Last modification on : Wednesday, September 16, 2020 - 10:43:28 AM

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Guillaume Lasserre, S. Bakkouch, Julien Pauchot, Delphine Binda, S. Robin, et al.. [Fingertip reconstruction with occlusive dressing: Clinical results and biological analysis of the dressing content's.]. Chirurgie de la Main, Elsevier Masson, 2010, epub ahead of print. ⟨10.1016/j.main.2010.03.011⟩. ⟨inserm-00508049⟩

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