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[The case series method].

Mounia Hocine 1, * Michel Chavance 2
* Corresponding author
1 Chaire d'Hygiène et sécurité du travail
CNAM - Conservatoire National des Arts et Métiers [CNAM]
Abstract : The case series method was developed by Farrington (1995) to investigate the strength of association between a time-varying exposure and an acute rare potentially recurrent event, using cases only. It can be used when the exposure can only be causally related to the event during a limited period of time. It has been widely used in pharmaco-epidemiology, particularly in the study of vaccine safety. The method is derived from a Poisson model by conditioning on the individual total number of events and its exposure history. As a consequence of this conditioning, the effects of fixed covariates cancel out, so that the method has a particular advantage as compared with cohort and case-control studies.
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Submitted on : Friday, November 26, 2010 - 2:41:15 PM
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Mounia Hocine, Michel Chavance. [The case series method].. Epidemiology and Public Health / Revue d'Epidémiologie et de Santé Publique, Elsevier Masson, 2010, 58 (6), pp.435-40. ⟨10.1016/j.respe.2010.06.168⟩. ⟨inserm-00498856⟩

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