D. A. Prince, Neurophysiology of Epilepsy, Annual Review of Neuroscience, vol.1, issue.1, pp.395-415, 1978.
DOI : 10.1146/annurev.ne.01.030178.002143

A. Obenaus, M. Esclapez, and C. R. Houser, Loss of glutamate decarboxylase mRNA-containing neurons in the rat dentate gyrus following pilocarpineinduced seizures, J. Neurosci, vol.13, pp.4470-4485, 1993.

R. S. Sloviter, Decreased hippocampal inhibition and a selective loss of interneurons in experimental epilepsy, Science, vol.235, issue.4784, pp.73-76, 1987.
DOI : 10.1126/science.2879352

C. R. Houser and M. Esclapez, Vulnerability and plasticity of the GABA system in the pilocarpine model of spontaneous recurrent seizures, Epilepsy Research, vol.26, issue.1, pp.207-218, 1996.
DOI : 10.1016/S0920-1211(96)00054-X

F. Morin, C. Beaulieu, and J. C. Lacaille, Selective loss of GABA neurons in area CA1 of the rat hippocampus after intraventricular kainate, Epilepsy Research, vol.32, issue.3, pp.363-369, 1998.
DOI : 10.1016/S0920-1211(98)00033-3

G. W. Mathern, T. L. Babb, J. K. Pretorius, and J. P. Leite, Reactive synaptogenesis and neuron densities for neuropeptide Y, somatostatin, and glutamate decarboxylase immunoreactivity in the epileptogenic human fascia dentata, J. Neurosci, vol.15, pp.3990-4004, 1995.

N. C. De-lanerolle, J. H. Kim, R. J. Robbins, and D. D. Spencer, Hippocampal interneuron loss and plasticity in human temporal lobe epilepsy, Brain Research, vol.495, issue.2, pp.387-395, 1989.
DOI : 10.1016/0006-8993(89)90234-5

R. J. Robbins, A selective loss of somatostatin in the hippocampus of patients with temporal lobe epilepsy, Annals of Neurology, vol.71, issue.3, pp.325-332, 1991.
DOI : 10.1002/ana.410290316

Z. Nusser, N. Hajos, P. Somogyi, and I. Mody, Increased number of synaptic GABA A receptors underlies potentiation at hippocampal inhibitory synapses, Nature, vol.395, issue.6698, pp.172-177, 1998.
DOI : 10.1038/25999

J. W. Gibbs, M. D. Shumate, and D. A. Coulter, Differential epilepsy-associated alterations in postsynaptic GABA(A) receptor function in dentate granule and CA1 neurons, J. Neurophysiol, vol.77, pp.1924-1938, 1997.

J. C. Hirsch, Deficit of quantal release of GABA in experimental models of temporal lobe epilepsy, Nat. Neurosci, vol.2, pp.499-500, 1999.
URL : https://hal.archives-ouvertes.fr/inserm-00486214

F. Loup, H. G. Wieser, Y. Yonekawa, A. Aguzzi, and J. M. Fritschy, Selective alterations in GABA A receptor subtypes in human temporal lobe epilepsy, J. Neurosci, vol.20, pp.5401-5419, 2000.

E. H. Buhl, T. S. Otis, and I. Mody, Zinc-Induced Collapse of Augmented Inhibition by GABA in a Temporal Lobe Epilepsy Model, Science, vol.271, issue.5247, pp.369-373, 1996.
DOI : 10.1126/science.271.5247.369

T. F. Freund and G. Buzsáki, Interneurons of the hippocampus, Hippocampus, vol.495, issue.1, pp.347-470, 1996.
DOI : 10.1002/(SICI)1098-1063(1996)6:4<347::AID-HIPO1>3.0.CO;2-I

URL : https://hal.archives-ouvertes.fr/inserm-00484796

R. Miles, K. Tóth, A. I. Gulyás, N. Hájos, and T. F. Freund, Differences between Somatic and Dendritic Inhibition in the Hippocampus, Neuron, vol.16, issue.4, pp.815-823, 1996.
DOI : 10.1016/S0896-6273(00)80101-4

I. Cohen and R. Miles, hippocampus, The Journal of Physiology, vol.261, issue.2, pp.485-502, 2000.
DOI : 10.1111/j.1469-7793.2000.00485.x

URL : https://hal.archives-ouvertes.fr/hal-00618368

C. R. Houser and M. Esclapez, Localization of mRNAs encoding two forms of glutamic acid decarboxylase in the rat hippocampal formation, Hippocampus, vol.280, issue.5, pp.530-545, 1994.
DOI : 10.1002/hipo.450040503

I. Katona, L. Acsady, and T. Freund, Postsynaptic targets of somatostatin-immunoreactive interneurons in the rat hippocampus, Neuroscience, vol.88, issue.1, pp.37-55, 1999.
DOI : 10.1016/S0306-4522(98)00302-9

K. Tóth and T. Freund, Calbindin D28k-containing nonpyramidal cells in the rat hippocampus: Their immunoreactivity for GABA and projection to the medial septum, Neuroscience, vol.49, issue.4, pp.793-805, 1992.
DOI : 10.1016/0306-4522(92)90357-8

D. Fricker, J. A. Verheugen, and R. Miles, Cell-attached measurements of the firing threshold of rat hippocampal neurones, The Journal of Physiology, vol.488, issue.3, pp.791-804, 1999.
DOI : 10.1111/j.1469-7793.1999.0791s.x

M. Esclapez, J. C. Hirsch, Y. Ben-ari, and C. Bernard, Newly formed excitatory pathways provide a substrate for hyperexcitability in experimental temporal lobe epilepsy, The Journal of Comparative Neurology, vol.851, issue.4, pp.449-460, 1999.
DOI : 10.1002/(SICI)1096-9861(19990614)408:4<449::AID-CNE1>3.0.CO;2-R

J. Lacaille and S. Williams, Membrane properties of interneurons in stratum oriens-alveus of the CA1 region of rat hippocampus in vitro, Neuroscience, vol.36, issue.2, pp.349-359, 1990.
DOI : 10.1016/0306-4522(90)90431-3

R. Cossart, Distribution of spontaneous currents along the somato-dendritic axis of rat hippocampal CA1 pyramidal neurons, Neuroscience, vol.99, issue.4, pp.593-603, 2000.
DOI : 10.1016/S0306-4522(00)00231-1

URL : https://hal.archives-ouvertes.fr/inserm-00484937

Y. Yanovsky, O. A. Sergeeva, T. F. Freund, and H. L. Haas, Activation of interneurons at the stratum oriens/alveus border suppresses excitatory transmission to apical dendrites in the CA1 area of the mouse hippocampus, Neuroscience, vol.77, issue.1, pp.87-96, 1997.
DOI : 10.1016/S0306-4522(96)00461-7

J. C. Hirsch, Enhanced NMDAR-dependent epileptiform activity is controlled by oxidizing agents in a chronic model of temporal lobe epilepsy, J. Neurophysiol, vol.76, pp.4185-4189, 1996.

G. Maccaferri and C. J. Mcbain, Passive propagation of LTD to stratum oriens-alveus inhibitory neurons modulates the temporoammonic input to the hippocampal CA1 region, Neuron, vol.15, issue.1, pp.137-145, 1995.
DOI : 10.1016/0896-6273(95)90071-3

P. S. Buckmaster and A. L. Jongen-relo, Highly specific neuron loss preserves lateral inhibitory circuits in the dentate gyrus of kainate-induced epileptic rats, J. Neurosci, vol.19, pp.9519-9529, 1999.

A. A. Oliva, M. Jiang, T. Lam, K. L. Smith, and J. W. Swann, Novel hippocampal interneuronal subtypes identified using transgenic mice that express green fluorescent protein in GABAergic interneurons, J. Neurosci, vol.20, pp.3354-3368, 2000.

Z. Liu, T. Nagao, G. C. Desjardins, P. Gloor, and M. Avoli, Quantitative evaluation of neuronal loss in the dorsal hippocampus in rats with long-term pilocarpine seizures, Epilepsy Res, vol.17, pp.237-247, 1994.

G. K. Pyapali and D. A. Turner, Denervation-induced dendritic alterations in CA1 pyramidal cells following kainic acid hippocampal lesions in rats, Brain Research, vol.652, issue.2, pp.279-290, 1994.
DOI : 10.1016/0006-8993(94)90238-0

C. R. Houser, Neuronal loss and synaptic reorganization in temporal lobe epilepsy, Adv. Neurol, vol.79, pp.743-761, 1999.

Y. Perez, F. Morin, C. Beaulieu, and J. Lacaille, Axonal Sprouting of CA1 Pyramidal Cells in Hyperexcitable Hippocampal Slices of Kainate-treated Rats, European Journal of Neuroscience, vol.44, issue.4, pp.736-748, 1996.
DOI : 10.1111/j.1460-9568.1996.tb01259.x

S. T. Ross and I. Soltesz, Selective depolarization of interneurons in the early posttraumatic dentate gyrus: involvement of the Na + /K + -ATPase, J. Neurophysiol, vol.83, pp.2916-2930, 2000.

D. A. Rempe, E. H. Bertram, J. M. Williamson, and E. W. Lothman, Interneurons in area CA1 stratum radiatum and stratum oriens remain functionally connected to excitatory synaptic input in chronically epileptic animals, J. Neurophysiol, vol.78, pp.1504-1515, 1997.

M. Esclapez, J. C. Hirsch, R. Khazipov, Y. Ben-ari, and C. Bernard, Operative GABAergic inhibition in hippocampal CA1 pyramidal neurons in experimental epilepsy, Proc. Natl. Acad. Sci. USA 94, pp.12151-12156, 1997.
DOI : 10.1073/pnas.94.22.12151

K. Chen, T. Z. Baram, and I. Soltesz, Febrile seizures in the developing brain result in persistent modifications of neuronal excitability in limbic circuits, Nat. Med, vol.5, pp.888-894, 1999.

D. A. Prince and K. Jacobs, Inhibitory function in two models of chronic epileptogenesis, Epilepsy Research, vol.32, issue.1-2, pp.83-92, 1998.
DOI : 10.1016/S0920-1211(98)00042-4

T. S. Otis, Y. De-koninck, and I. Mody, Lasting potentiation of inhibition is associated with an increased number of gamma-aminobutyric acid type A receptors activated during miniature inhibitory postsynaptic currents., Proc. Natl. Acad. Sci. USA. 91, pp.7698-7702, 1994.
DOI : 10.1073/pnas.91.16.7698

J. C. Magee and E. P. Cook, Somatic EPSP amplitude is independent of synapse location in hippocampal pyramidal neurons, Nature Neuroscience, vol.3, issue.9, pp.895-903, 2000.
DOI : 10.1038/78800

W. R. Holmes and W. B. Levy, Quantifying the role of inhibition in associative longterm potentiation in dentate granule cells with computational models

A. Kapur, W. W. Lytton, K. L. Ketchum, and L. B. Haberly, Regulation of the NMDA component of EPSPs by different components of postsynaptic GABAergic inhibition: Computer simulation analysis in piriform cortex, J. Neurophysiol, vol.78, pp.2546-2559, 1997.

D. Johnston, D. A. Hoffman, C. M. Colbert, and J. C. Magee, Regulation of back-propagating action potentials in hippocampal neurons, Current Opinion in Neurobiology, vol.9, issue.3, pp.288-292, 1999.
DOI : 10.1016/S0959-4388(99)80042-7

J. Nadler, Kainic acid as a tool for the study of temporal lobe epilepsy, Life Sciences, vol.29, issue.20, pp.2031-2042, 1981.
DOI : 10.1016/0024-3205(81)90659-7

D. L. Kaufman, J. F. Mcginnis, N. R. Krieger, and A. J. Tobin, Brain glutamate decarboxylase cloned in lambda gt-11: fusion protein produces gamma-aminobutyric acid, Science, vol.232, issue.4754, pp.1138-1140, 1986.
DOI : 10.1126/science.3518061

R. H. Goodman, J. W. Jacobs, P. C. Dee, and J. Habener, Somatostatin-28 encoded in a cloned cDNA obtained from a rat medullary thyroid carcinoma, J. Biol. Chem, vol.257, pp.1156-1159, 1982.

M. Esclapez, N. J. Tillakaratne, D. L. Kaufman, A. J. Tobin, and C. Houser, Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the forms, J. Neurosci, vol.14, pp.1834-1855, 1994.

D. L. Kaufman, C. R. Houser, and A. J. Tobin, Two Forms of the ?-Aminobutyric Acid Synthetic Enzyme Glutamate Decarboxylase Have Distinct Intraneuronal Distributions and Cofactor Interactions, Journal of Neurochemistry, vol.34, issue.2, pp.720-723, 1991.
DOI : 10.1016/0022-2836(86)90385-2

A. Peters and S. L. Palay, The morphology of synapses, Journal of Neurocytology, vol.221, issue.Suppl., pp.687-700, 1996.
DOI : 10.1007/BF02284835