Region-specific regulation of glutamic acid decarboxylase (GAD) mRNA expression in central stress circuits, J Neurosci, vol.18, pp.5938-5947, 1998. ,
Highly specific cell loss of only one interneuron class in the dentate gyrus of kainate-induced epileptic rats, Epilepsia, vol.39, p.136, 1998. ,
Neuron loss, granule cell axon reorganization, and functional changes in the dentate gyrus of epileptic kainate-treated rats, The Journal of Comparative Neurology, vol.15, issue.3, pp.385-404, 1997. ,
DOI : 10.1002/(SICI)1096-9861(19970901)385:3<385::AID-CNE4>3.0.CO;2-#
Agonist, Journal of Neurochemistry, vol.259, issue.2, pp.428-435, 1991. ,
DOI : 10.1073/pnas.83.24.9827
Receptors in the Regulation of Glutamic Acid Decarboxylase Messenger RNA in the Striatum of the Rat, European Journal of Neuroscience, vol.259, issue.5, pp.438-447, 1992. ,
DOI : 10.1111/j.1460-9568.1992.tb00894.x
The susceptibility of rats to pilocarpine-induced seizures is age-dependent, Developmental Brain Research, vol.37, issue.1-2, pp.43-58, 1987. ,
DOI : 10.1016/0165-3806(87)90227-6
Long-Term Effects of Pilocarpine in Rats: Structural Damage of the Brain Triggers Kindling and Spontaneous I Recurrent Seizures, Epilepsia, vol.4, issue.6, pp.778-782, 1991. ,
DOI : 10.1002/syn.890030207
Spontaneous Recurrent Seizures in Rats: Amino Acid and Monoamine Determination in the Hippocampus, Epilepsia, vol.228, issue.1, pp.1-11, 1994. ,
DOI : 10.1016/0014-2999(87)90468-7
Characterization of the proteins purified with monoclonal antibodies to glutamic acid decarboxylase, J Neurosci, vol.8, pp.2123-2130, 1988. ,
Chronic seizures and collateral sprouting of dentate mossy fibers after kainic acid treatment in rats, Brain Research, vol.474, issue.1, pp.181-184, 1988. ,
DOI : 10.1016/0006-8993(88)90681-6
Sprouting of GABAergic and mossy fiber axons in dentate gyrus following intrahippocampal kainate in the rat, Experimental Neurology, vol.109, issue.2, pp.180-190, 1990. ,
DOI : 10.1016/0014-4886(90)90072-Z
Unilateral nigrostriatal lesions induce a bilateral increase in glutamate decar???ylase messenger rna in the reticular thalamic nucleus, Neuroscience, vol.71, issue.2, pp.383-395, 1996. ,
DOI : 10.1016/0306-4522(95)00470-X
Rapid increases in cerebellar Purkinje cell glutamic acid decar???ylase (GAD67) mRNA after lesion-induced increases in cell firing, Brain Research, vol.615, issue.1, pp.175-179, 1993. ,
DOI : 10.1016/0006-8993(93)91129-G
Adrenergic agents inhibit rapid increases in cerebellar Purkinje cell glutamic acid decarboxylase (GAD 67 ) mRNA levels after climbing fiber lesions or reserpine treatment, J Neurosci, vol.16, pp.1844-1851, 1996. ,
The structural and functional heterogeneity of glutamic acid decarboxylase: A review, Neurochemical Research, vol.14, issue.3, pp.215-226, 1991. ,
DOI : 10.1007/BF00966084
Two genes encode distinct glutamate decarboxylases, Neuron, vol.7, issue.1, pp.91-100, 1991. ,
DOI : 10.1016/0896-6273(91)90077-D
Comparative localization of mRNAs encoding two forms of glutamic acid decarboxylase with nonradioactive in situ hybridization methods, The Journal of Comparative Neurology, vol.8, issue.3, pp.339-362, 1993. ,
DOI : 10.1002/cne.903310305
Comparative localization of two forms of glutamic acid decarboxylase and their mRNAs in rat brain supports the concept of functional differences between the forms, J Neurosci, vol.14, pp.1834-1855, 1994. ,
Operative GABAergic inhibition in hippocampal CA1 pyramidal neurons in experimental epilepsy, Proceedings of the National Academy of Sciences, vol.94, issue.22, pp.12151-12156, 1997. ,
DOI : 10.1073/pnas.94.22.12151
GABA release and GAD67 mRNA expression in rat hippocampus following entorhinal cortex activation, Molecular Brain Research, vol.48, issue.2, pp.413-416, 1997. ,
DOI : 10.1016/S0169-328X(97)00185-X
Long term increase of glutamate decarboxylase mRNA in a rat model of temporal lobe epilepsy, Neuron, vol.5, issue.3, pp.361-371, 1990. ,
DOI : 10.1016/0896-6273(90)90172-C
GABAergic axon terminals at perisomatic and dendritic inhibitory sites show different immunoreactivities against two GAD isoforms, GAD67 and GAD65, in the mouse hippocampus: A digitized quantitative analysis, The Journal of Comparative Neurology, vol.78, issue.2, pp.177-194, 1998. ,
DOI : 10.1002/(SICI)1096-9861(19980601)395:2<177::AID-CNE3>3.0.CO;2-#
Differential epilepsy-associated alterations in postsynaptic GABA A receptor function in dentate granule and CAI neurons, J Neurophysiol, vol.77, pp.1924-1938, 1997. ,
The effects of varying key steps in the non-radioactive in situ hybridization protocol: a quantitative study, The Histochemical Journal, vol.41, issue.1, pp.60-68, 1995. ,
DOI : 10.1007/BF00164173
with the hapten digoxigenin (DIG); hybridization and ELISA-based detection, Nucleic Acids Research, vol.18, issue.19, pp.5843-5851, 1990. ,
DOI : 10.1093/nar/18.19.5843
GAD65 mRNA and protein labeling are increased in remaining hippocampal GABA neurons in a model of temporal lobe epilepsy, Soc Neurosci Abstr, vol.20, p.408, 1994. ,
Localization of mRNAs encoding two forms of glutamic acid decarboxylase in the rat hippocampal formation, Hippocampus, vol.280, issue.5, pp.530-545, 1994. ,
DOI : 10.1002/hipo.450040503
Vulnerability and plasticity of the GABA system in the pilocarpine model of spontaneous recurrent seizures, Epilepsy Research, vol.26, issue.1, pp.207-218, 1996. ,
DOI : 10.1016/S0920-1211(96)00054-X
Brain glutamate decarboxylase cloned in lambda gt-11: fusion protein produces gamma-aminobutyric acid, Science, vol.232, issue.4754, pp.1138-1140, 1986. ,
DOI : 10.1126/science.3518061
Two Forms of the ?-Aminobutyric Acid Synthetic Enzyme Glutamate Decarboxylase Have Distinct Intraneuronal Distributions and Cofactor Interactions, Journal of Neurochemistry, vol.34, issue.2, pp.720-723, 1991. ,
DOI : 10.1016/0022-2836(86)90385-2
Glutamic acid decarboxylase cDNA: nucleotide sequence encoding an enzymatically active fusion protein, J Neurosci, vol.7, pp.2768-2772, 1987. ,
Differential regulation of mRNA levels encoding for the two isoforms of glutamate decarboxylase (GAD65 and GAD67) by dopamine receptors in the rat striatum, Molecular Brain Research, vol.34, issue.1, pp.65-74, 1995. ,
DOI : 10.1016/0169-328X(95)00139-J
MK-801 decreases striatal and cortical GAD65 mRNA levels, NeuroReport, vol.6, issue.14, pp.1885-1889, 1995. ,
DOI : 10.1097/00001756-199510020-00015
Glutamate decarboxylase (GAD65) gene expression is increased by dopamine receptor agonists in a subpopulation of rat striatal neurons, Molecular Brain Research, vol.48, issue.2, pp.333-345, 1997. ,
DOI : 10.1016/S0169-328X(97)00112-5
Optimization of non-radioactive in situ hybridization: image analysis of varying pretreatment, hybridization and probe labelling conditions, Histochemistry, vol.3, issue.4, pp.347-354, 1990. ,
DOI : 10.1007/BF00315849
Sensitive detection of rat gastrin mRNA by in situ hybridization with chemically biotinylated oligodeoxynucleotides: validation, quantitation, and double-staining studies., Journal of Histochemistry & Cytochemistry, vol.41, issue.2, pp.157-163, 1993. ,
DOI : 10.1177/41.2.8419457
Evidence for paracrine somatostatinergic regulation of gastrin gene expression by double-staining cytochemistry and quantitation., Journal of Histochemistry & Cytochemistry, vol.42, issue.1, pp.37-40, 1994. ,
DOI : 10.1177/42.1.7903328
Glass slide models for immunocytochemistry and in situ hybridization, Histochemistry, vol.34, issue.5, pp.325-331, 1994. ,
DOI : 10.1007/BF00268993
Quantitative nonradioactive in situ hybridization. Model studies and studies on pituitary proopiomelanocortin cells after adrenalectomy, Histochemistry, vol.95, pp.209-215, 1991. ,
Increased glutamic acid decarboxylase (GAD) mRNA and GAD activity in cerebellar Purkinje cells following lesion-induced increases in cell firing, Neuroscience Letters, vol.116, issue.1-2, pp.179-183, 1990. ,
DOI : 10.1016/0304-3940(90)90406-Y
In situ hybridization histochemistry: a new method for processing material stored for several years, Brain Research, vol.578, issue.1-2, pp.155-160, 1992. ,
DOI : 10.1016/0006-8993(92)90243-3
Regulation of ?-Aminobutyric Acid Synthesis in the Brain, Journal of Neurochemistry, vol.42, issue.2, pp.395-407, 1993. ,
DOI : 10.1016/0169-328X(90)90016-7
Cofactor interactions and the regulation of glutamate decarboxylase activity, Neurochemical Research, vol.6, issue.suppl 2, pp.243-249, 1991. ,
DOI : 10.1007/BF00966087
Regulatory properties of brain glutamate decarboxylase (GAD): the apoenzyme of GAD is present principally as the smaller of two molecular forms of GAD in brain, J Neurosci, vol.11, pp.2725-2731, 1991. ,
Reactive synaptogenesis and neuron densities for neuropeptide Y, somatostatin, and glutamate decarboxylase immunoreactivity in the epileptogenic human fascia dentata, J Neurosci, vol.15, pp.3990-4004, 1995. ,
Estrogen modulation of mRNA levels for the two forms of glutamic acid decarboxylase (GAD) in female rat brain, The Journal of Comparative Neurology, vol.19, issue.4, pp.685-697, 1995. ,
DOI : 10.1002/cne.903600412
Circuit Mechanisms of Seizures in the Pilocarpine Model of Chronic Epilepsy: Cell Loss and Mossy Fiber Sprouting, Epilepsia, vol.200, issue.6, pp.985-995, 1993. ,
DOI : 10.1002/syn.890030207
Selective loss of GABA neurons in area CA1 of the rat hippocampus after intraventricular kainate, Epilepsy Research, vol.32, issue.3, pp.363-369, 1998. ,
DOI : 10.1016/S0920-1211(98)00033-3
Fate of the hippocampal mossy fiber projection after destruction of its postsynaptic targets with intraventricular kainic acid, The Journal of Comparative Neurology, vol.76, issue.4, pp.549-569, 1981. ,
DOI : 10.1002/cne.901960404
Loss of glutamate decarboxylase mRNA-containing neurons in the rat dentate gyrus following pilocarpine-induced seizures, J Neurosci, vol.13, pp.4470-4485, 1993. ,
Interneurons in area CA1 stratum radiatum and stratum oriens remain functionally connected to excitatory synaptic input in chronically epileptic animals, J Neurophysiol, vol.45, pp.1504-1515, 1997. ,
Increased Intracellular ?-Aminobutyric Acid Selectively Lowers the Level of the Larger of Two Glutamate Decarboxylase Proteins in Cultured GABAergic Neurons from Rat Cerebral Cortex, Journal of Neurochemistry, vol.47, issue.1, pp.158-166, 1992. ,
DOI : 10.1016/0165-3806(81)90005-5
The Level of GAD67 Protein Is Highly Sensitive to Small Increases in Intraneuronal ??-Aminobutyric Acid Levels, Journal of Neurochemistry, vol.35, issue.4, pp.1375-1381, 1994. ,
DOI : 10.1046/j.1471-4159.1994.62041375.x
Protein and mRNA Levels in Rat Cerebral Cortex, Journal of Neurochemistry, vol.47, issue.2, pp.714-720, 1993. ,
DOI : 10.1016/0169-328X(90)90016-7
Hippocampal granule cells express glutamic acid decar???ylase-67 after limbic seizures in the rat, Neuroscience, vol.69, issue.3, pp.705-709, 1995. ,
DOI : 10.1016/0306-4522(95)00348-M
Somatostatin, neuropeptide Y, neurokinin B and cholecystokinin immunoreactivity in two chronic models of temporal lobe epilepsy, Neuroscience, vol.69, issue.3, pp.831-845, 1995. ,
DOI : 10.1016/0306-4522(95)00268-N
Permanently altered hippocampal structure, excitability, and inhibition after experimental status epilepticus in the rat: The ?dormant basket cell? hypothesis and its possible relevance to temporal lobe epilepsy, Hippocampus, vol.15, issue.1, pp.41-66, 1991. ,
DOI : 10.1002/hipo.450010106
Basal expression and induction of glutamate decarboxylase GABA in excitatory granule cells of the rat and monkey hippocampal dentate gyrus, The Journal of Comparative Neurology, vol.46, issue.4, pp.593-618, 1996. ,
DOI : 10.1002/(SICI)1096-9861(19960930)373:4<593::AID-CNE8>3.0.CO;2-X
Effects of nigrostriatal lesions on the levels of messenger RNAs encoding two isoforms of glutamate decarboxylase in the globus pallidus and entopeduncular nucleus of the rat, Synapse, vol.1, issue.2, pp.124-133, 1992. ,
DOI : 10.1002/syn.890110205
Messenger RNAs encoding glutamate-decar???ylases are differentially affected by nigrostriatal lesions in subpopulations of striatal neurons, Brain Research, vol.576, issue.1, pp.68-79, 1992. ,
DOI : 10.1016/0006-8993(92)90610-L
Patch-clamp recordings reveal powerful GABAergic inhibition in dentate hilar neurons, J Neurosci, vol.14, issue.4, pp.2365-2376, 1994. ,
Functional changes in neuropeptide Y- and somatostatin-containing neurons induced by limbic seizures in the rat, Neuroscience, vol.50, issue.4, pp.831-846, 1992. ,
DOI : 10.1016/0306-4522(92)90207-I
Synaptic reorganization in the hippocampus induced by abnormal functional activity, Science, vol.239, issue.4844, pp.1147-1150, 1988. ,
DOI : 10.1126/science.2449733
Limbic seizures produced by pilocarpine in rats: Behavioural, electroencephalographic and neuropathological study, Behavioural Brain Research, vol.9, issue.3, pp.315-336, 1983. ,
DOI : 10.1016/0166-4328(83)90136-5
Seizures produced by pilocarpine: Neuropathological sequelae and activity of glutamate decarboxylase in the rat forebrain, Brain Research, vol.398, issue.1, pp.37-48, 1986. ,
DOI : 10.1016/0006-8993(86)91247-3
Use of cryoprotectant to maintain long-term peptide immunoreactivity and tissue morphology, Peptides, vol.7, issue.1, pp.155-159, 1986. ,
DOI : 10.1016/0196-9781(86)90076-8
Aging-related changes in rat striatal D 2 receptor mRNA-containing neurons: a quantitative nonradioactive in situ hybridization study, J Neurosci, vol.15, pp.1735-1740, 1995. ,