Complex links between dietary lipids, endogenous endotoxins and metabolic inflammation.

Fabienne Laugerette; Cécile Vors; Noël Peretti; Marie-Caroline Michalski

doi:10.1016/j.biochi.2010.04.016

Complex links between dietary lipids, endogenous endotoxins and metabolic inflammation.

Fabienne Laugerette ¹ Cécile Vors ¹ Noël Peretti ^{2, 3} Marie-Caroline Michalski ^{4, 3, *}

* Auteur correspondant

1 CarMeN - Cardiovasculaire, métabolisme, diabétologie et nutrition

2 CHLS - Centre Hospitalier Lyon Sud [CHU - HCL]

3 RMND UM55 - Régulations métaboliques, nutrition et diabètes - UM55

4 CRNH - Centre de Recherche en Nutrition Humaine Rhône-Alpes

Abstract : Metabolic diseases such as obesity are characterized by a subclinical inflammatory state that contributes to the development of insulin resistance and atherosclerosis. Recent reports also indicate that (i) there are alterations of the intestinal microbiota in metabolic diseases and (ii) absorption of endogenous endotoxins (namely lipopolysaccharides, LPS) can occur, particularly during the digestion of lipids. The aim of the present review is to highlight recently gained knowledge regarding the links between high fat diets, lipid digestion, intestinal microbiota and metabolic endotoxemia & inflammation.

Type de document :

Article dans une revue

Biochimie, Elsevier, 2011, 93 (1), pp.39-45. 〈10.1016/j.biochi.2010.04.016〉

Domaine :

Sciences du Vivant [q-bio] / Alimentation et Nutrition

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http://www.hal.inserm.fr/inserm-00486698
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Soumis le : mercredi 26 mai 2010 - 12:40:16
Dernière modification le : mardi 17 juillet 2018 - 15:49:43
Document(s) archivé(s) le : jeudi 1 décembre 2016 - 02:39:29

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