Importance de l'examen macroscopique et du compte rendu histologique dans la prise en charge thérapeutique des tumeurs du rein. [Importance of the macroscopic examination and histologic report in the therapeutic management of kidney tumors]
Abstract
The most important parameters in predicting outcome in renal cell carcinoma are the pathologic and clinical stage, nuclear grade and histologic type. The recent literature has highlighted the increasing importance of pathologic findings in decision making for patients with renal tumors. A checklist based approach to reporting the relevant pathologic details of renal cell carcinoma resection specimens improves the completeness of the report. First the importance of distinguishing different tumor types has been underscored by dramatic variation in prognosis and the development of targeted therapies for specific subtypes. Second, the increasing number of recognized renal neoplasms has implications for handling renal resection specimens. Guidelines for handling of renal resection specimens will focus on problem areas in the evolving practice of diagnosis, grading, and staging of renal tumors for an optimal therapy.
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