Skip to Main content Skip to Navigation
Journal articles

Molecular basis of programmed cell death involved in neurodegeneration.

Abstract : Rapid progress in understanding the molecular basis of neurodegeneration has been tightly linked with recent discoveries in the field of programmed cell death (PCD). Analysis of PCD in neuronal demise has led to identification of several associated phenomena, such as re-initiation of the cell cycle and the key role of oxidative stress, although putative causal relationships between these events are still debatable. These issues are reviewed here in the context of acute and chronic neurodegenerative processes. In addition, newly emerging concepts concerning cell-cycle re-initiation are discussed in terms of their potential impact on the development of more effective therapeutic strategies.
Document type :
Journal articles
Complete list of metadatas

Cited literature [74 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00484536
Contributor : Roman Tyzio <>
Submitted on : Tuesday, May 18, 2010 - 3:31:20 PM
Last modification on : Thursday, June 18, 2020 - 12:32:04 PM
Long-term archiving on: : Wednesday, November 30, 2016 - 10:16:54 PM

File

 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document

Identifiers

Collections

Citation

Slavica Krantic, Naguib Mechawar, Stéphanie Reix, Rémi Quirion. Molecular basis of programmed cell death involved in neurodegeneration.. Trends in Neurosciences, Elsevier, 2005, 28 (12), pp.670-6. ⟨10.1016/j.tins.2005.09.011⟩. ⟨inserm-00484536⟩

Share

Metrics

Record views

165