Meiotic spindle assembly and chromosome segregation in oocytes - Inserm - Institut national de la santé et de la recherche médicale Access content directly
Book Sections Year : 2010

Meiotic spindle assembly and chromosome segregation in oocytes


Oogenesis - the process by which female germ cells develop into mature eggs, or ova - is a complex process involving many important elements of developmental and cellular biology: from cell-cell interactions, complex signalling cascades, specialized cell cycles and cytoskeleton organization. Oocytes from various species (including clam, starfish, xenopus and mouse) are excellent model systems to study the biochemistry of cell division with important implications for basic and clinical research. This book describes the entire process of oogenesis in chronological order with contributions from leading international researchers and chapters covering medical and ethical considerations in oogenic biology. Topics include sex determination and gonadal development, control of meiotic chromosome pairing and homologous recombination, control of meiotic divisions and the remodelling of the oocyte into a totipotent zygote as well as medically-assisted reproduction.
Embargoed file
Embargoed file
Ne sera jamais visible

Dates and versions

inserm-00481524 , version 1 (06-05-2010)


  • HAL Id : inserm-00481524 , version 1


Julien Dumont, Stéphane Brunet. Meiotic spindle assembly and chromosome segregation in oocytes. MH Verlhac and A Villeneuve. Oogenesis: the universal process, John wiley & sons, Ltd, pp.269-290, 2010. ⟨inserm-00481524⟩
165 View
1 Download


Gmail Facebook Twitter LinkedIn More