Skip to Main content Skip to Navigation
Journal articles

Gluten intolerance and skin diseases.

Abstract : Gluten sensitivity with or without coeliac disease (CD) symptoms and intestinal pathology has been suggested as a potentially treatable cause of various diseases. CD is a chronic disease which improves on withdrawal of wheat gliadins and barley, rye and oat prolamins from the diet. There have been numerous reports linking CD with several skin conditions. A body of evidence shows that dermatitis herpetiformis is actually a cutaneous manifestation of CD. Autoimmune diseases, allergic diseases, psoriasis and miscellaneous diseases have also been described with gluten intolerance. Dermatologists should be familiar with the appraisal of gluten sensitive enteropathy and should be able to search for an underlying gluten intolerance (GI). Serological screening by means of antigliadin, antiendomysial and transglutaminase antibodies should be performed. HLA typing is often useful in association with serologic tests. Intestinal biopsy is usually needed to establish the diagnosis of CD or GI. Thus, gluten intolerance gives rise to a variety of dermatological manifestations which may benefit from a gluten-free diet.
Document type :
Journal articles
Complete list of metadatas

https://www.hal.inserm.fr/inserm-00473376
Contributor : Philippe Saas <>
Submitted on : Thursday, April 15, 2010 - 11:04:04 AM
Last modification on : Tuesday, October 27, 2020 - 2:35:49 PM

Identifiers

  • HAL Id : inserm-00473376, version 1
  • PUBMED : 16436335

Collections

Citation

Philippe Humbert, Fabien Pelletier, Brigitte Dreno, Eve Puzenat, François Aubin. Gluten intolerance and skin diseases.. European Journal of Dermatology, John Libbey Eurotext, 2006, 16 (1), pp.4-11. ⟨inserm-00473376⟩

Share

Metrics

Record views

223