T. Kamradt and N. Mitchison, Tolerance and autoimmunity, N Engl J Med, vol.344, pp.655-64, 2001.

S. Sakaguchi, Regulatory T Cells, Cell, vol.101, issue.5, pp.455-463, 2000.
DOI : 10.1016/S0092-8674(00)80856-9

URL : https://hal.archives-ouvertes.fr/hal-01358192

E. Shevach, CD4+ CD25+ suppressor T cells: more questions than answers, Nat. Rev. Immunol, vol.2, pp.389-400, 2002.

K. Wood and S. Sakaguchi, Regulatory Lymphocytes: Regulatory T cells in transplantation tolerance, Nature Reviews Immunology, vol.3, issue.3, pp.199-210, 2003.
DOI : 10.1038/nri1027

J. Cohen, A. Trenado, D. Vasey, D. Klatzmann, and B. Salomon, Immunoregulatory T Cells, The Journal of Experimental Medicine, vol.141, issue.3, pp.401-407, 2002.
DOI : 10.1016/S0167-5699(98)01420-0

URL : https://hal.archives-ouvertes.fr/hal-00018382

P. Hoffmann, J. Ermann, M. Edinger, C. Fathman, and S. Strober, Regulatory T Cells Suppress Lethal Acute Graft-Versus-Host Disease after Allogeneic Bone Marrow Transplantation, The Journal of Experimental Medicine, vol.131, issue.3, pp.389-99, 2002.
DOI : 10.4049/jimmunol.164.1.183

C. Piccirillo, J. Letterio, A. Thornton, R. Mchugh, M. Mamura et al., CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness, J. Exp, 2002.

H. Groux, O. Garra, A. Bigler, M. Rouleau, M. Antonenko et al., A CD4+ T-cell subset inhibits antigen-specific T-cell responses and prevents colitis, Nature, vol.389, pp.737-779, 1997.

H. Weiner, Induction and mechanism of action of transforming growth factor-beta-secreting Th3 regulatory cells, Immunological Reviews, vol.182, issue.1, pp.207-221, 2001.
DOI : 10.1034/j.1600-065X.2001.1820117.x

J. Fontenot, M. Gavin, and A. Rudensky, Foxp3 programs the development and function of CD4+CD25+ regulatory T cells, Nature Immunology, vol.4, issue.4, pp.330-336, 2003.
DOI : 10.1038/ni904

S. Hori, T. Nomura, and S. Sakaguchi, Control of Regulatory T Cell Development by the Transcription Factor Foxp3, Science, vol.299, issue.5609, pp.1057-61, 2003.
DOI : 10.1126/science.1079490

R. Khattri, T. Cox, S. Yasayko, and F. Ramsdell, An essential role for Scurfin in CD4+CD25+ T regulatory cells, Nature Immunology, vol.4, issue.4, pp.337-379, 2003.
DOI : 10.1038/ni909

M. Fantini, C. Becker, G. Monteleone, F. Pallone, P. Galle et al., Cutting Edge: TGF-?? Induces a Regulatory Phenotype in CD4+CD25- T Cells through Foxp3 Induction and Down-Regulation of Smad7, The Journal of Immunology, vol.172, issue.9, pp.5149-53, 2004.
DOI : 10.4049/jimmunol.172.9.5149

S. Fu, N. Zhang, A. Yopp, D. Chen, M. Mao et al., TGF-beta Induces Foxp3 + T-Regulatory Cells from CD4 + CD25 - Precursors, American Journal of Transplantation, vol.167, issue.10, pp.1614-1641, 2004.
DOI : 10.1084/jem.188.2.287

E. Sun and Y. Shi, Apoptosis: the quiet death silences the immune system, Pharmacology & Therapeutics, vol.92, issue.2-3, pp.135-180, 2001.
DOI : 10.1016/S0163-7258(01)00164-4

R. Steinman, S. Turley, I. Mellman, and K. Inaba, The Induction of Tolerance by Dendritic Cells That Have Captured Apoptotic Cells, Journal of Experimental Medicine, vol.191, issue.3, pp.411-417, 2000.
DOI : 10.1084/jem.191.3.411

M. Albert, Opinion: Death-defying immunity: do apoptotic cells influence antigen processing and presentation?, Nature Reviews Immunology, vol.104, issue.3, pp.223-254, 2004.
DOI : 10.1038/nri11308

URL : https://hal.archives-ouvertes.fr/pasteur-01402360

V. Fadok, D. Bratton, A. Konowal, P. Freed, J. Westcott et al., Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF., Journal of Clinical Investigation, vol.101, issue.4, 1998.
DOI : 10.1172/JCI1112

F. Huang, N. Platt, M. Wykes, J. Major, T. Powell et al., A Discrete Subpopulation of Dendritic Cells Transports Apoptotic Intestinal Epithelial Cells to T Cell Areas of Mesenteric Lymph Nodes, Journal of Experimental Medicine, vol.188, issue.11, pp.435-479, 2000.
DOI : 10.1084/jem.188.11.2163

T. Iyoda, S. Shimoyama, K. Liu, Y. Omatsu, Y. Akiyama et al., Dendritic Cell Subset Selectively Endocytoses Dying Cells in Culture and In Vivo, The Journal of Experimental Medicine, vol.157, issue.10, pp.1289-302, 2002.
DOI : 10.4049/jimmunol.167.9.4844

K. Liu, T. Iyoda, M. Saternus, Y. Kimura, K. Inaba et al., Immune Tolerance After Delivery of Dying Cells to Dendritic Cells In Situ, The Journal of Experimental Medicine, vol.61, issue.8, pp.1091-1098, 2002.
DOI : 10.1073/pnas.93.7.3031

A. Morelli, A. Larregina, W. Shufesky, A. Zahorchak, A. Logar et al., Internalization of circulating apoptotic cells by splenic marginal zone dendritic cells: dependence on complement receptors and effect on cytokine production, Blood, vol.101, issue.2, pp.611-631, 2003.
DOI : 10.1182/blood-2002-06-1769

S. Gallucci and P. Matzinger, Danger signals: SOS to the immune system, Current Opinion in Immunology, vol.13, issue.1, pp.114-123, 2001.
DOI : 10.1016/S0952-7915(00)00191-6

R. Voll, M. Herrmann, E. Roth, C. Stach, J. Kalden et al., Immunosuppressive effects of apoptotic cells, Nature, vol.390, issue.6658, pp.350-351, 1997.
DOI : 10.1038/37022

M. Huynh, V. Fadok, and P. Henson, Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-??1 secretion and the resolution of inflammation, Journal of Clinical Investigation, vol.109, issue.1, pp.41-50, 2002.
DOI : 10.1172/JCI0211638

A. Byrne and D. Reen, Lipopolysaccharide Induces Rapid Production of IL-10 by Monocytes in the Presence of Apoptotic Neutrophils, The Journal of Immunology, vol.168, issue.4, pp.1968-77, 2002.
DOI : 10.4049/jimmunol.168.4.1968

W. Chen, M. Frank, J. W. Wahl, and S. , TGF-?? Released by Apoptotic T Cells Contributes to an Immunosuppressive Milieu, Immunity, vol.14, issue.6, pp.715-740, 2001.
DOI : 10.1016/S1074-7613(01)00147-9

Y. Gao, J. Herndon, H. Zhang, T. Griffith, and T. Ferguson, Antiinflammatory Effects of CD95 Ligand (FasL)-induced Apoptosis, The Journal of Experimental Medicine, vol.159, issue.5, pp.887-96, 1998.
DOI : 10.1016/0167-5699(96)80556-1

S. Adler and L. Turka, Immunotherapy as a means to induce transplantation tolerance, Current Opinion in Immunology, vol.14, issue.5, pp.660-665, 2002.
DOI : 10.1016/S0952-7915(02)00376-X

M. Bittencourt, S. Perruche, E. Contassot, S. Fresnay, M. Baron et al., Intravenous injection of apoptotic leukocytes enhances bone marrow engraftment across major histocompatibility barriers, Blood, vol.98, issue.1, pp.224-254, 2001.
DOI : 10.1182/blood.V98.1.224

P. Leenen, K. Radosevic, J. Voerman, B. Salomon, N. Van-rooijen et al., Heterogeneity of mouse spleen dendritic cells: in vivo phagocytic activity, expression of macrophage markers, and subpopulation turnover, J. Immunol, vol.160, pp.2166-73, 1998.

B. Blazar, F. Lindberg, E. Ingulli, A. Panoskaltsis-mortari, P. Oldenborg et al., Cd47 (Integrin-Associated Protein) Engagement of Dendritic Cell and Macrophage Counterreceptors Is Required to Prevent the Clearance of Donor Lymphohematopoietic Cells, The Journal of Experimental Medicine, vol.30, issue.4, pp.541-550, 2001.
DOI : 10.1074/jbc.271.1.21

S. Jung, D. Unutmaz, P. Wong, G. Sano, K. De-los-santos et al., In Vivo Depletion of CD11c+ Dendritic Cells Abrogates Priming of CD8+ T Cells by Exogenous Cell-Associated Antigens, vivo depletion of CD11c(+) dendritic cells abrogates priming of CD8(+) T cells by exogenous cellassociated antigens, pp.211-231, 2002.
DOI : 10.1016/S1074-7613(02)00365-5

S. Perruche, F. Kleinclauss, M. Bittencourt, D. Paris, P. Tiberghien et al., Intravenous Infusion of Apoptotic Cells Simultaneously with Allogeneic Hematopoietic Grafts Alters Anti-Donor Humoral Immune Responses, American Journal of Transplantation, vol.3, issue.8, pp.1361-1366, 2004.
DOI : 10.1038/71472

V. Fadok, D. Bratton, D. Rose, A. Pearson, R. Ezekewitz et al., A receptor for phosphatidylserine-specific clearance of apoptotic cells, Nature, vol.405, issue.6782, pp.85-90, 2000.
DOI : 10.1038/35011084

S. Perruche, F. Kleinclauss, R. Angonin, J. Cahn, E. Deconinck et al., A single intravenous infusion of apoptotic cells, p.30, 2003.

J. Letterio and A. Roberts, REGULATION OF IMMUNE RESPONSES BY TGF-??, Annual Review of Immunology, vol.16, issue.1, pp.137-61, 1998.
DOI : 10.1146/annurev.immunol.16.1.137

A. Bushell, M. Karim, C. Kingsley, and K. Wood, Pretransplant blood transfusion without additional immunotherapy generates CD25+CD4+ regulatory T cells: a potential explanation for the blood-transfusion effect, Transplantation, vol.76, issue.3, pp.449-55, 2003.
DOI : 10.1097/01.TP.0000083043.84630.99

W. Dzik, Apoptosis, TGF?? and transfusion-related immunosuppression: Biologic versus clinical effects, Transfusion and Apheresis Science, vol.29, issue.2, pp.127-136, 2003.
DOI : 10.1016/S1473-0502(03)00115-0

E. Snyder and D. Kuter, Apoptosis in transfusion medicine:of death and dying-is that all there is?, Transfusion, vol.68, issue.2, pp.135-143, 2000.
DOI : 10.1046/j.1537-2995.1998.38111299056320.x

E. Sun, Y. Gao, J. Chen, A. Roberts, X. Wang et al., Allograft tolerance induced by donor apoptotic lymphocytes requires phagocytosis in the recipient, Cell Death and Differentiation, vol.11, issue.12, pp.1258-64, 2004.
DOI : 10.1038/sj.cdd.4401500

V. Fadok, D. Bratton, and P. Henson, Phagocyte receptors for apoptotic cells: recognition, uptake, and consequences, Journal of Clinical Investigation, vol.108, issue.7, pp.957-62, 2001.
DOI : 10.1172/JCI14122DS1

J. Kobie, R. Wu, R. Kurt, S. Lou, M. Adelman et al., Transforming growth factor beta inhibits the antigen-presenting functions and antitumor activity of dendritic cell vaccines, Cancer Res, vol.63, pp.1860-1864, 2003.

M. Walker, D. Kasprowicz, V. Gersuk, A. Benard, M. Van-landeghen et al., Induction of FoxP3 and acquisition of T regulatory activity by stimulated human CD4+CD25??? T cells, Journal of Clinical Investigation, vol.112, issue.9, pp.1437-1480, 2003.
DOI : 10.1172/JCI19441

I. Apostolou, V. Boehmer, and H. , In Vivo Instruction of Suppressor Commitment in Naive T Cells, The Journal of Experimental Medicine, vol.155, issue.10, pp.1401-1409, 2004.
DOI : 10.1126/science.1078231

S. Liang, P. Alard, Y. Zhao, S. Parnell, S. Clark et al., regulatory T cells in vivo requires B7 costimulation, but not the thymus, The Journal of Experimental Medicine, vol.162, issue.1, pp.127-164, 2005.
DOI : 10.1084/jem.20040249

Y. Colson, K. Christopher, J. Glickman, K. Taylor, R. Wright et al., Absence of clinical GVHD and the in vivo induction of regulatory T cells after transplantation of facilitating cells, Blood, vol.104, issue.12, pp.3829-3864, 2004.
DOI : 10.1182/blood-2004-01-0393

P. Taylor, A. Panoskaltsis-mortari, J. Swedin, P. Lucas, R. Gress et al., L-Selectinhi but not the L-selectinlo CD4+25+ T-regulatory cells are potent inhibitors of GVHD and BM graft rejection, Blood, vol.104, issue.12, pp.3804-3816, 2004.
DOI : 10.1182/blood-2004-05-1850

A. Hanash and R. Levy, Donor CD4+CD25+ T cells promote engraftment and tolerance following MHC-mismatched hematopoietic cell transplantation, Blood, vol.105, issue.4, pp.1828-1864, 2005.
DOI : 10.1182/blood-2004-08-3213

E. Contassot, C. Ferrand, R. Angonin, J. Cohen, M. De-carvalho-bittencourt et al., GANCICLOVIR-SENSITIVE ACUTE GRAFT-VERSUS-HOST DISEASE IN MICE RECEIVING HERPES SIMPLEX VIRUS-THYMIDINE KINASE???EXPRESSING DONOR T CELLS IN A BONE MARROW TRANSPLANTATION SETTING1, Transplantation, vol.69, issue.4, pp.503-511, 2000.
DOI : 10.1097/00007890-200002270-00007

I. Dumitriu, W. Mohr, W. Kolowos, P. Kern, J. Kalden et al., 5,6-Carboxyfluorescein Diacetate Succinimidyl Ester-Labeled Apoptotic and Necrotic as Well as Detergent-Treated Cells Can Be Traced in Composite Cell Samples, Analytical Biochemistry, vol.299, issue.2, pp.247-52, 2001.
DOI : 10.1006/abio.2001.5415

S. Perruche, F. Kleinclauss, A. Lienard, R. E. Tiberghien, P. Saas et al., A single-platform approach using flow cytometry and microbeads to evaluate immune reconstitution in mice after bone marrow transplantation, Journal of Immunological Methods, vol.294, issue.1-2, pp.53-66, 2004.
DOI : 10.1016/j.jim.2004.08.011