Skip to Main content Skip to Navigation
Journal articles

Role of dietary iodine and cruciferous vegetables in thyroid cancer: a countrywide case-control study in New Caledonia.

Abstract : Exceptionally high incidence rates of thyroid cancer have been reported in New Caledonia, particularly in Melanesian women. To clarify the reasons of this elevated incidence, we conducted a countrywide population-based case-control study in the multiethnic population of Caledonian women. The study included 293 cases of thyroid cancer and 354 population controls. Based on a food frequency questionnaire, we investigated the role in thyroid cancer of food items rich in iodine-such as seafood-and of vegetables containing goitrogens-such as cruciferous vegetables. A measure of total daily iodine intake based on a food composition table was also used. Our findings provided little support for an association between thyroid cancer and consumption of fish and seafood. We found that high consumption of cruciferous vegetables was associated with thyroid cancer among women with low iodine intake (OR = 1.86; 95% CI: 1.01-3.43 for iodine intake <96 microg/day). The high consumption of cruciferous vegetables among Melanesian women, a group with mild iodine deficiency, may contribute to explain the exceptionally high incidence of thyroid cancer in this group.
Document type :
Journal articles
Complete list of metadatas

Cited literature [7 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00471339
Contributor : Nadine Kaniewski <>
Submitted on : Thursday, April 8, 2010 - 9:39:15 AM
Last modification on : Wednesday, September 16, 2020 - 5:06:40 PM
Long-term archiving on: : Tuesday, September 14, 2010 - 5:46:21 PM

Files

dietary_factors_in_thyroid_can...
Files produced by the author(s)

Identifiers

Collections

Citation

Thérèse Truong, Dominique Baron-Dubourdieu, Yannick Rougier, Pascal Guénel. Role of dietary iodine and cruciferous vegetables in thyroid cancer: a countrywide case-control study in New Caledonia.. Cancer Causes and Control, Springer Verlag, 2010, 21 (8), pp.1183-92. ⟨10.1007/s10552-010-9545-2⟩. ⟨inserm-00471339⟩

Share

Metrics

Record views

483

Files downloads

1306