Dynamic MR urography in urinary tract obstruction: implementation and preliminary results.

Catherine Lefort 1, 2 Nolwenn Marouteau-Pasquier 3 Anne-Sophie Pesquet 3 Christian Pfister 4 Pierre Vera 1, 5 Jean-Nicolas Dacher 1, 3
1 QuantIF-LITIS - Equipe Quantification en Imagerie Fonctionnelle
LITIS - Laboratoire d'Informatique, de Traitement de l'Information et des Systèmes
2 Service de radiologie
3 Service d'imagerie médicale [Rouen]
4 Service d'urologie [Rouen]
5 Service de médecine nucléaire [Rouen]
Abstract : BACKGROUND: Recent studies have demonstrated magnetic resonance (MR) capabilities in evaluating renal morphology and function in patients with urinary obstruction. The objective of this report is to support the introduction of dynamic MR renography on any MR equipment. METHODS: A custom-made device of vials filled with different concentrations of gadolinium was studied by combinations of T1-weighted gradient-echo sequences and coils. We compared the capabilities of two coils (phased array vs. standard body), the properties of dynamic sequences, and the effects of increasing concentrations of gadolinium on signal intensity. In a second section, we designed MR urography plug-ins of Image J (DICOM image software) for the analysis of dynamic studies. RESULTS: Optimized gradient-echo sequences acquired with a phased array body coil produced acceptable quality images with a linear relation between signal intensity and the lowest concentrations of gadolinium. In vitro measurements showed loss of linearity above 8 mmol/L. CONCLUSION: Theoretical calculation and data from the literature suggest that the gadolinium dose to the patient should not exceed one-fourth of the usual one (0.025 mmol/kg). Postprocessing using Image J software and the specifically designed plug-ins was validated. The collection of plug-ins is now available on the Internet.
Type de document :
Article dans une revue
Abdominal Imaging, Springer Verlag, 2006, 31 (2), pp.232-40. 〈10.1007/s00261-005-0391-8〉
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http://www.hal.inserm.fr/inserm-00467293
Contributeur : Céline Breton <>
Soumis le : vendredi 26 mars 2010 - 13:09:42
Dernière modification le : mardi 2 octobre 2018 - 01:17:00

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BECQUEREL | FNCLCC | COMUE-NORMANDIE | LITIS | INSA-ROUEN | UNIROUEN

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Catherine Lefort, Nolwenn Marouteau-Pasquier, Anne-Sophie Pesquet, Christian Pfister, Pierre Vera, et al.. Dynamic MR urography in urinary tract obstruction: implementation and preliminary results.. Abdominal Imaging, Springer Verlag, 2006, 31 (2), pp.232-40. 〈10.1007/s00261-005-0391-8〉. 〈inserm-00467293〉

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