Participants' uptake of clinical trial results: a randomised experiment.: Informing participants about trial results via Internet

Julien Mancini 1, 2 Dominique Genre 3 Florence Dalenc 4, 5 Jean-Marc Ferrero 6, 7 Pierre Kerbrat 8 Anne-Laure Martin 9 Henri Roché 4 F. Maylevin 10 Carole Tarpin 3 Patrice Viens 1, 3 Jean Genève 9 Claire Julian-Reynier 1, *
* Auteur correspondant
1 SESSTIM - U912 INSERM - AMU - IRD - Sciences Economiques et Sociales de la Santé & Traitement de l'Information Médicale
2 SSPIM - Service de Santé Publique et d'Information Médicale
3 CRCM - Centre de Recherche en Cancérologie de Marseille
4 Institut Claudius Regaud
5 Departement /u563 : Oncogenèse, Signalisation et Innovation thérapeutique
Centre de Physiopathologie Toulouse Purpan (ex IFR 30 et IFR 150), Institut Claudius Regaud
6 Centre Antoine Lacassagne
7 ISARA-LYON - Ecole d'Ingénieurs en Agriculture, Développement rural et Agroalimentaire
8 CRLCC - CRLCC Eugène Marquis
9 FNCLCC - Fédération Nationale des Centres de Lutte Contre le Cancer
10 Comités de patients FNCLCC
Abstract : BACKGROUND: Participants are showing great interest these days in obtaining the results of clinical trials. The aim of this study was to assess patients' uptake and understanding of the results of the trial in which they have participated and the impact of a letter offering patients the possibility of consulting the trial results on a specific website. METHODS: Breast cancer patients participating in a trial on the efficacy of Trastuzumab were randomly subdivided into an Internet group (who received the letter of invitation) and a control group (who did not receive it). Among 115 HER2-positive women from 21 centres, 107 (93%) answered a self-administered questionnaire. RESULTS: Most of the patients in both groups had access to the Internet (72.0%). The majority (97.2%) stated that receiving information about the trial results would be useful, and the oncologist was the most frequently preferred information provider. The Internet group's declared uptake of the trial results was only slightly higher (47.1% vs 33.9%; P=0.166); however, they understood the results significantly more accurately (18.8% vs 5.6%; P=0.039). INTERPRETATION: Although Internet was not the respondents' preferred source of information, the possibility of using this source slightly increased the uptake and understanding of the results.
Keywords : Breast cancer Randomised controlled trials Informing patients
Type de document :
Article dans une revue
British Journal of Cancer, Cancer Research UK, 2010, 102 (7), pp.1081-4. 〈10.1038/sj.bjc.6605592〉
Liste complète des métadonnées

Littérature citée [12 références]  Voir  Masquer  Télécharger
http://www.hal.inserm.fr/inserm-00465844
Contributeur : Julien Mancini <>
Soumis le : lundi 22 mars 2010 - 10:26:31
Dernière modification le : mardi 11 septembre 2018 - 16:20:02
Document(s) archivé(s) le : lundi 28 juin 2010 - 15:52:34

Fichier

JM_BJC_10_inpress.pdf
Accord explicite pour ce dépôt

Identifiants

Collections

UNIV-TLSE3 | ICR | IRD | PAOLI_CALMETTES | LACASSAGNE | FNCLCC | MARQUIS | UNIV-AMU | UNIV-LILLE3

Citation

Julien Mancini, Dominique Genre, Florence Dalenc, Jean-Marc Ferrero, Pierre Kerbrat, et al.. Participants' uptake of clinical trial results: a randomised experiment.: Informing participants about trial results via Internet. British Journal of Cancer, Cancer Research UK, 2010, 102 (7), pp.1081-4. 〈10.1038/sj.bjc.6605592〉. 〈inserm-00465844〉

Exporter

BibTeX TEI DC DCterms EndNote

Partager

Métriques

Consultations de la notice

647

Téléchargements de fichiers

170

Contact

support.ccsd.cnrs.fr
hal.support@ccsd.cnrs.fr
Logo CCSD