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Pressure stability with CPAP devices: A bench evaluation.

Abstract : BACKGROUND: Continuous positive airway pressure (CPAP) maintains a constant pressure to reduce the patient's work of breathing (WOB). The aim of this study was to measure the additional WOB imposed by four current CPAP devices during simulation of a difficult but commonly encountered clinical situation. METHOD: Flow contour, respiratory system compliance and total lung-airway resistance of a patient under CPAP were simulated. The devices were tested at a CPAP of 15cm H(2)O with a heated humidifier and a nasal pillow, which increased circuitry resistance and with and without a simulated unintentional leak. RESULTS: With no leak, positive end-expiratory pressure (PEEP) at the interface varied across devices from 14.0 to 15.3cm H(2)O. With a leak of 1L/s, PEEP varied from 11.5 to 17.1cm H(2)O. Imposed inspiratory WOB ranged from less than 0.1J/min to 0.45J/min with no leak, and the range broadened with leaking. Findings were similar for the imposed expiratory WOB. CONCLUSION: The performances of CPAP devices are variable. The device that calibrated for the pressure loss in the circuitry under dynamic conditions and made appropriate pressure adjustments outperformed the other devices.
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https://www.hal.inserm.fr/inserm-00459003
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Submitted on : Tuesday, February 23, 2010 - 8:06:51 AM
Last modification on : Wednesday, August 19, 2020 - 11:16:57 AM
Long-term archiving on: : Friday, June 18, 2010 - 9:40:38 PM

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Bruno Louis, Karl Leroux, Maud Boucherie, Daniel Isabey, Véronique Grillier-Lanoir, et al.. Pressure stability with CPAP devices: A bench evaluation.. Sleep Medicine, Elsevier, 2010, 11 (1), pp.96-9. ⟨10.1016/j.sleep.2009.02.011⟩. ⟨inserm-00459003⟩

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