A revival of bispecific antibodies, Trends in Biotechnology, vol.22, issue.5, pp.238-282, 2004. ,
DOI : 10.1016/j.tibtech.2004.03.006
Hybrid antibodies can target sites for attack by T cells, Nature, vol.157, issue.6012, pp.628-659, 1985. ,
DOI : 10.1038/314628a0
Preparation and performance of bispecific F(ab' gamma)2 antibody containing thioether-linked Fab' gamma fragments, J Immunol, vol.139, pp.2367-75, 1987. ,
Isolation and characterization of anti-Fc??RIII (CD16) llama single-domain antibodies that activate natural killer cells, Protein Engineering Design and Selection, vol.21, issue.1, pp.1-10, 2008. ,
DOI : 10.1093/protein/gzm064
URL : https://hal.archives-ouvertes.fr/hal-00258940
Recombinant bispecific antibodies for cellular cancer immunotherapy, Curr Opin Mol Ther, vol.9, pp.319-345, 2007. ,
Tumor Regression in Cancer Patients by Very Low Doses of a T Cell-Engaging Antibody, Science, vol.321, issue.5891, pp.974-981, 2008. ,
DOI : 10.1126/science.1158545
Naturally occurring antibodies devoid of light chains, Nature, vol.363, issue.6428, pp.446-454, 1993. ,
DOI : 10.1038/363446a0
CD3??????CD28 cross-interacting bispecific antibodies improve tumor cell dependent T-cell activation, Cancer Immunology, Immunotherapy, vol.786, issue.1???2, pp.1059-71, 2005. ,
DOI : 10.1007/s00262-005-0671-8
Simultaneous targeting of multiple disease mediators by a dual-variable-domain immunoglobulin, Nature Biotechnology, vol.97, issue.11, pp.1290-1297, 2007. ,
DOI : 10.1038/nbt1345
BiTE: A new class of antibodies that recruit T-cells, Drugs of the Future, vol.33, issue.2, pp.137-147, 2008. ,
DOI : 10.1358/dof.2008.033.02.1172578
In vitro and in vivo targeting of radiolabeled monovalent and divalent haptens with dual specificity monoclonal antibody conjugates: enhanced divalent hapten affinity for cell-bound antibody conjugate, J Nucl Med, vol.30, pp.1358-66, 1989. ,
Cancer imaging and therapy with bispecific antibody pretargeting, Update on Cancer Therapeutics, vol.2, issue.1, pp.19-31, 2007. ,
DOI : 10.1016/j.uct.2007.04.003
Multifunctional Antibodies by the Dock-and-Lock Method for Improved Cancer Imaging and Therapy by Pretargeting, Journal of Nuclear Medicine, vol.49, issue.1, pp.158-63, 2008. ,
DOI : 10.2967/jnumed.107.046185
Tumor targeting with newly designed biparatopic antibodies directed against two different epitopes of the carcinoembryonic antigen (CEA), International Journal of Cancer, vol.75, issue.2, pp.285-91, 1999. ,
DOI : 10.1002/(SICI)1097-0215(19990412)81:2<285::AID-IJC19>3.0.CO;2-T
Targeting of Human Breast Cancer by a Bispecific Antibody Directed against Two Tumour-Associated Antigens: ErbB-2 and Carcinoembryonic Antigen, Tumor Biology, vol.23, issue.6, pp.337-384 ,
DOI : 10.1159/000069793
Targeting ErbB2 and ErbB3 with a bispecific single-chain Fv enhances targeting selectivity and induces a therapeutic effect in vitro, British Journal of Cancer, vol.5, issue.9, pp.1415-1440, 2008. ,
DOI : 10.1038/sj.bjc.6604700
A Fully Human Recombinant IgG-like Bispecific Antibody to Both the Epidermal Growth Factor Receptor and the Insulin-like Growth Factor Receptor for Enhanced Antitumor Activity, Journal of Biological Chemistry, vol.280, issue.20, pp.19665-72, 2005. ,
DOI : 10.1074/jbc.M500815200
Bispecific anti-CD20/22 antibodies inhibit B-cell lymphoma proliferation by a unique mechanism of action, Blood, vol.111, issue.4, pp.2211-2220, 2008. ,
DOI : 10.1182/blood-2007-08-110072