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Cell cycle regulators in the control of metabolism.: Cell cycle and metabolism.

Abstract : We recently showed that the CDK4-pRB-E2F1 cell cycle regulators directly regulate the expression of Kir6.2, which is a key component of the K(ATP) channel involved in the regulation of glucose-induced insulin secretion. There is enough evidence to indicate that the CDK4-pRB-E2F1 regulatory pathway is involved in general glucose homeostasis, and metabolism. In this article we discuss which are the metabolic implications of these findings.
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https://www.hal.inserm.fr/inserm-00442943
Contributor : Yves Le Ster <>
Submitted on : Monday, March 19, 2012 - 9:59:01 AM
Last modification on : Tuesday, July 7, 2020 - 3:18:58 PM
Long-term archiving on: : Wednesday, June 20, 2012 - 2:21:26 AM

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Emilie Blanchet, Jean-Sébastien Annicotte, Lluis Fajas. Cell cycle regulators in the control of metabolism.: Cell cycle and metabolism.. Cell Cycle, Taylor & Francis, 2009, 8 (24), pp.4029-31. ⟨10.4161/cc.8.24.10110⟩. ⟨inserm-00442943⟩

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