Synthesis and pharmacological characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, silicon analogues of the RARalpha-selective retinoid agonists AM80 (Tamibarotene) and AM580.

Reinhold Tacke; Volker Müller; Matthias Büttner; W Peter Lippert; Rüdiger Bertermann; Jürgen Daiss; Harshal Khanwalkar; Audrey Furst; Claudine Gaudon; Hinrich Gronemeyer

doi:10.1002/cmdc.200900257

Journal articles

Synthesis and pharmacological characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, silicon analogues of the RARalpha-selective retinoid agonists AM80 (Tamibarotene) and AM580.

Reinhold Tacke ¹ Volker Müller ¹ Matthias Büttner ¹ W Peter Lippert ¹ Rüdiger Bertermann ¹ Jürgen Daiss ¹ Harshal Khanwalkar ² Audrey Furst ² Claudine Gaudon ² Hinrich Gronemeyer ²

1 Institut für Anorganische Chemie

2 IGBMC - Institut de Génétique et de Biologie Moléculaire et Cellulaire

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Synthesis and pharmacological characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, silicon analogues of the RARalpha-selective retinoid agonists AM80 (Tamibarotene) and AM580.

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Synthesis and pharmacological characterization of Disila-AM80 (Disila-tamibarotene) and Disila-AM580, silicon analogues of the RARalpha-selective retinoid agonists AM80 (Tamibarotene) and AM580.

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