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Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis.

Abstract : Endothelial cells lining the vessel wall are connected by adherens, tight and gap junctions. These junctional complexes are related to those found at epithelial junctions but with notable changes in terms of specific molecules and organization. Endothelial junctional proteins play important roles in tissue integrity but also in vascular permeability, leukocyte extravasation and angiogenesis. In this review, we will focus on specific mechanisms of endothelial tight and adherens junctions.
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https://www.hal.inserm.fr/inserm-00433167
Contributor : Philippe Huber <>
Submitted on : Wednesday, November 18, 2009 - 1:00:22 PM
Last modification on : Friday, November 6, 2020 - 4:03:58 AM
Long-term archiving on: : Thursday, June 17, 2010 - 8:50:51 PM

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Yann Wallez, Philippe Huber. Endothelial adherens and tight junctions in vascular homeostasis, inflammation and angiogenesis.. Biochimica et Biophysica Acta - Molecular Cell Research, Elsevier, 2008, 1778 (3), pp.794-809. ⟨10.1016/j.bbamem.2007.09.003⟩. ⟨inserm-00433167⟩

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