I. Guessous, J. Cornuz, and P. , Lung cancer screening: current situation and perspective, Swiss Med Wkly, vol.137, pp.304-311, 2007.

S. Desagher, A. Osen-sand, A. Nichols, R. Eskes, S. Montessuit et al., Bid-induced Conformational Change of Bax Is Responsible for Mitochondrial Cytochrome c Release during Apoptosis, The Journal of Cell Biology, vol.391, issue.5, pp.891-901, 1999.
DOI : 10.1074/jbc.272.39.24101

H. Asahina, K. Yamazaki, I. Kinoshita, N. Sukoh, M. Harada et al., A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations, British Journal of Cancer, vol.311, issue.8, pp.998-1004, 2006.
DOI : 10.1093/annonc/mdi340

J. Engelman, P. Janne, C. Mermel, J. Pearlberg, T. Mukohara et al., ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines, Proceedings of the National Academy of Sciences, vol.102, issue.10, pp.3788-3793, 2005.
DOI : 10.1073/pnas.0409773102

R. Sordella, . Bell, . Dw, . Haber, and S. Da, Gefitinib-Sensitizing EGFR Mutations in Lung Cancer Activate Anti-Apoptotic Pathways, Science, vol.305, issue.5687, pp.1163-1167, 2004.
DOI : 10.1126/science.1101637

S. Tracy, T. Mukohara, M. Hansen, M. Meyerson, . Johnson et al., Gefitinib Induces Apoptosis in the EGFRL858R Non-Small-Cell Lung Cancer Cell Line H3255, Cancer Research, vol.64, issue.20, pp.7241-7244, 2004.
DOI : 10.1158/0008-5472.CAN-04-1905

T. Miyashita, S. Krajewski, M. Krajewska, . Wang, . Hg et al., Tumor suppressor p53 is a regulator of bcl-2 and bax gene expression in vitro and in vivo, Oncogene, vol.9, pp.1799-1805, 1994.

F. Morgillo, . Woo, . Jk, . Kim, . Es et al., Heterodimerization of insulin-like growth factor receptor/epidermal growth factor receptor and induction inserm-00425468, version 1 -21 Oct 2009 invasion and tumor-induced angiogenesis, induces apoptosis in vitro and inhibits tumor growth in vivo in glioblastoma, Oncogene, vol.27, pp.4830-4840, 2006.

J. Yoo, J. Kim, J. Kim, J. Huang, . Zhang et al., Short hairpin RNA-expressing oncolytic adenovirus-mediated inhibition of IL-8: effects on antiangiogenesis and tumor growth inhibition, Gene Therapy, vol.73, issue.9, pp.635-651, 2008.
DOI : 10.1038/sj.bjc.6690811

I. Kjonniksen, R. Storeng, A. Pihl, T. Mclemore, and O. Fodstad, A human tumor lung metastasis model in athymic nude rats, Cancer Res, vol.49, pp.5148-5152, 1989.