A robust Expectation-Maximization algorithm for Multiple Sclerosis lesion segmentation

Daniel García-Lorenzo 1, * Sylvain Prima 1 Sean Patrick Morrissey 1, 2 Christian Barillot 1
* Corresponding author
1 VisAGeS - Vision, Action et Gestion d'informations en Santé
INSERM - Institut National de la Santé et de la Recherche Médicale : U746, Inria Rennes – Bretagne Atlantique , IRISA-D5 - SIGNAUX ET IMAGES NUMÉRIQUES, ROBOTIQUE
Abstract : A fully automatic workflow for Multiple Sclerosis (MS) lesion segmentation is described. Fully automatic means that no user interaction is performed in any of the steps and that all parameters are fixed for all the images processed in beforehand. Our workflow is composed of three steps: an intensity inhomogeneity (IIH) correction, skull-stripping and MS lesions segmentation. A validation comparing our results with two experts is done on MS MRI datasets of 24 MS patients from two different sites.
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Daniel García-Lorenzo, Sylvain Prima, Sean Patrick Morrissey, Christian Barillot. A robust Expectation-Maximization algorithm for Multiple Sclerosis lesion segmentation. MICCAI Workshop: 3D Segmentation in the Clinic: A Grand Challenge II, MS lesion segmentation, Sep 2008, New York, United States. pp.277. ⟨inserm-00421713⟩

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