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Evaluation of in-stent restenosis in proximal coronary arteries with multidetector computed tomography (MDCT).

Abstract : The purpose of this study was to assess the ability of 16-slice computed tomography (CT) to detect in-stent restenosis of proximal coronary arteries. From November 2002 to April 2004, 134 consecutive patients with proximal stents (3.25 +/- 0.47 mm) were prospectively studied. Multidetector CT (MDCT) was performed 24 h (baseline) and 6 months after angioplasty and analysed by two radiologists blinded to the results of the coronary angiography. Sensitivity, specificity, positive and negative predictive values for in-stent restenosis were compared with conventional quantitative coronary angiography (QCA). Stenosis with a diameter >or=50% was considered diagnostic of in-stent restenosis. The CT analysis was performed in 131 and 114 patients at baseline and 6 months, respectively. The in-stent lumen was evaluable in 111 (121 stents) and 99 patients (108 stents) at baseline and 6 months, respectively. The prevalence of in-stent restenosis was 22.5%. Restenoses were correctly identified in 91.7 and 87.5% by the two radiologists. The sensitivity, specificity, positive and negative predictive values for the assessment of significant in-stent restenosis were 92, 67, 43, 97% and 87, 66, 41, 95% for the radiologists, respectively. MDCT is a potential non-invasive technique for the screening of in-stent restenosis of proximal coronary arteries that needs further improvements.
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https://www.hal.inserm.fr/inserm-00420545
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Submitted on : Tuesday, September 29, 2009 - 11:55:47 AM
Last modification on : Wednesday, July 8, 2020 - 3:01:28 AM

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Valérie Chabbert, Didier Carrié, Mehdi Bennaceur, E. Maupas, Valérie Lauwers, et al.. Evaluation of in-stent restenosis in proximal coronary arteries with multidetector computed tomography (MDCT).. European Radiology, Springer Verlag, 2007, 17 (6), pp.1452-63. ⟨10.1007/s00330-006-0510-0⟩. ⟨inserm-00420545⟩

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