Skip to Main content Skip to Navigation
Journal articles

Heart rate increment analysis is not effective for sleep-disordered breathing screening in patients with chronic heart failure.

Abstract : Frequency domain analysis of heart rate variation has been suggested as an effective screening tool for sleep-disordered breathing (SDB) in the general population. The aim of this study was to assess this method in patients with chronic congestive heart failure (CHF). We included prospectively 84 patients with stable CHF, left ventricular ejection fraction (LVEF) <45% and sinus rhythm. The patients underwent polygraphy to measure the apnoea/hypopnoea index (AHI) and simultaneous Holter electrocardiogram monitoring to measure the power spectral density of the very low frequency component of the heart rate increment, expressed as the percentage of total power spectral density [% very low frequency increment (%VLFI)]. %VLFI could be determined in 54 patients (mean age, 52.8 +/- 12.3 years; LVEF, 33.5 +/- 9.8%). SDB defined as AHI > or =15 h(-1) was diagnosed in 57.4% of patients. Percent VLFI was not correlated with AHI (r = 0.12). Receiver-operating characteristic curves constructed using various AHI cut-offs (5-30 h(-1)) failed to identify a %VLFI cut-off associated with SDB. The 2.4% VLFI cut-off recommended for the general population of patients with suspected SDB had low specificity (35%) and low positive and negative predictive values (35% and 54%, respectively). Heart rate increment analysis has several limitations in CHF patients and cannot be recommended as an SDB screening tool in the CHF population.
Document type :
Journal articles
Complete list of metadatas

https://www.hal.inserm.fr/inserm-00414782
Contributor : Georges Guellaen <>
Submitted on : Thursday, September 10, 2009 - 8:31:42 AM
Last modification on : Wednesday, August 19, 2020 - 11:16:30 AM
Long-term archiving on: : Saturday, November 26, 2016 - 12:48:38 PM

Files

 Restricted access
To satisfy the distribution rights of the publisher, the document is embargoed until : jamais

Please log in to resquest access to the document

  •  Damy_tables_JSR_2009.pdf    Embargoed until : jamais  Files produced by the author(s)

Identifiers

Collections

Citation

Thibaud Damy, Marie-Pia d'Ortho, Brigitte Estrugo, Laurent Margarit, Gauthier Mouillet, et al.. Heart rate increment analysis is not effective for sleep-disordered breathing screening in patients with chronic heart failure.. Journal of Sleep Research, Wiley, 2010, 19 (1 Pt 2), pp.131-8. ⟨10.1111/j.1365-2869.2009.00779.x⟩. ⟨inserm-00414782⟩

Share

Metrics

Record views

270