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[Therapeutic agents targetting protein-protein interactions: myth or reality?]

Abstract : Protein-protein interactions have a key role in transduction pathways that regulate many cellular functions. Structural and functional properties of protein-protein interface are now better understood, therefore offering attractive opportunities for therapeutic intervention. Developping small molecules that modulate protein-protein interactions is challenging. Nethertheless, significant progress in this endeavour has been made on several fronts. Here, we use few illustrative examples to summarize recent work in this emerging field.
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Journal articles
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https://www.hal.inserm.fr/inserm-00413234
Contributor : Claude Cochet <>
Submitted on : Thursday, September 3, 2009 - 3:22:29 PM
Last modification on : Wednesday, February 5, 2020 - 3:46:02 PM

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  • HAL Id : inserm-00413234, version 1
  • PUBMED : 17349288

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Béatrice Laudet, Renaud Prudent, Odile Filhol, Claude Cochet. [Therapeutic agents targetting protein-protein interactions: myth or reality?]. médecine/sciences, EDP Sciences, 2007, 23 (3), pp.273-8. ⟨inserm-00413234⟩

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