C. C. Berry, G. Campbell, A. Spadiccino, M. Robertson, and A. S. Curtis, The influence of microscale topography on fibroblast attachment and motility, Biomaterials, vol.25, issue.26, pp.255781-5788, 2004.
DOI : 10.1016/j.biomaterials.2004.01.029

J. L. Bos, Linking Rap to cell adhesion, Current Opinion in Cell Biology, vol.17, issue.2, pp.123-128, 2005.
DOI : 10.1016/j.ceb.2005.02.009

R. Bruinsma, Theory of Force Regulation by Nascent Adhesion Sites, Biophysical Journal, vol.89, issue.1, pp.87-94, 2005.
DOI : 10.1529/biophysj.104.048280

F. Castellano, P. Montcourrier, J. C. Guillemot, E. Gouin, L. Machesky et al., Inducible recruitment of Cdc42 or WASP to a cell-surface receptor triggers actin polymerization and filopodium formation, Current Biology, vol.9, issue.7, pp.351-360, 1999.
DOI : 10.1016/S0960-9822(99)80161-4

F. Chamaraux, O. Ali, S. Keller, F. Bruckert, and B. Fourcade, Physical model for membrane protrusions during spreading, Physical Biology, vol.5, issue.3, p.36009, 2008.
DOI : 10.1088/1478-3975/5/3/036009

URL : https://hal.archives-ouvertes.fr/inserm-00347311

F. Chamaraux, S. Fache, F. Bruckert, and B. Fourcade, Kinetics of Cell Spreading, Physical Review Letters, vol.94, issue.15, pp.158102-158102, 2005.
DOI : 10.1103/PhysRevLett.94.158102

E. S. Chhabra and H. N. Higgs, The many faces of actin: matching assembly factors with cellular structures, Nature Cell Biology, vol.207, issue.10, pp.1110-1121, 2007.
DOI : 10.1038/222641a0

C. Choi, M. Vicente-manzanares, J. Zareno, L. Whitmore, A. Mogilner et al., Actin and alpha-actinin orchestrate the assembly and maturation of nascent adhesions in a myosin ii motor-independent manner, Nat Cell Biol, 2008.

A. Curtis and C. Wilkinson, Topographical control of cells, Biomaterials, vol.18, issue.24, pp.1573-1583, 1997.
DOI : 10.1016/S0142-9612(97)00144-0

D. Cuvelier, M. Thery, Y. Chu, S. Dufour, J. Thiery et al., The Universal Dynamics of Cell Spreading, Current Biology, vol.17, issue.8, pp.17694-699, 2007.
DOI : 10.1016/j.cub.2007.02.058

N. O. Deakin and C. E. Turner, Paxillin comes of age, Journal of Cell Science, vol.121, issue.15, pp.2435-2444, 2008.
DOI : 10.1242/jcs.018044

K. A. Demali, K. Wennerberg, and K. Burridge, Integrin signaling to the actin cytoskeleton, Current Opinion in Cell Biology, vol.15, issue.5, pp.572-582, 2003.
DOI : 10.1016/S0955-0674(03)00109-1

H. Dobereiner, B. J. Dubin-thaler, G. Giannone, and M. P. Sheetz, Force sensing and generation in cell phases: analyses of complex functions, Journal of Applied Physiology, vol.98, issue.4, pp.1542-1548, 2005.
DOI : 10.1152/japplphysiol.01181.2004

B. J. Dubin-thaler, J. M. Hofman, Y. Cai, H. Xenias, I. Spielman et al., Quantification of Cell Edge Velocities and Traction Forces Reveals Distinct Motility Modules during Cell Spreading, PLoS ONE, vol.91, issue.1, p.3735, 2008.
DOI : 10.1371/journal.pone.0003735.s009

A. J. Engler, S. Sen, H. L. Sweeney, and D. E. Discher, Matrix Elasticity Directs Stem Cell Lineage Specification, Cell, vol.126, issue.4, pp.677-689, 2006.
DOI : 10.1016/j.cell.2006.06.044

URL : http://doi.org/10.1016/j.cell.2006.06.044

B. M. Filippi, S. Mariggio, T. Pulvirenti, and D. Corda, SRC-dependent signalling regulates actin ruffle formation induced by glycerophosphoinositol 4-phosphate, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, vol.1783, issue.12, pp.17832311-2322, 2008.
DOI : 10.1016/j.bbamcr.2008.07.021

URL : http://doi.org/10.1016/j.bbamcr.2008.07.021

P. Friedl, Prespecification and plasticity: shifting mechanisms of cell migration, Current Opinion in Cell Biology, vol.16, issue.1, pp.14-23, 2004.
DOI : 10.1016/j.ceb.2003.11.001

G. Giannone, B. J. Dubin-thaler, O. Rossier, Y. Cai, O. Chaga et al., Lamellipodial Actin Mechanically Links Myosin Activity with Adhesion-Site Formation, Cell, vol.128, issue.3, pp.128561-575, 2007.
DOI : 10.1016/j.cell.2006.12.039

URL : http://doi.org/10.1016/j.cell.2006.12.039

G. Giannone and M. P. Sheetz, Substrate rigidity and force define form through tyrosine phosphatase and kinase pathways, Trends in Cell Biology, vol.16, issue.4, pp.213-223, 2006.
DOI : 10.1016/j.tcb.2006.02.005

M. H. Ginsberg, A. Partridge, and S. J. Shattil, Integrin regulation, Current Opinion in Cell Biology, vol.17, issue.5, pp.509-516, 2005.
DOI : 10.1016/j.ceb.2005.08.010

H. Guillou, A. Depraz-depland, E. Planus, B. Vianay, J. Chaussy et al., Lamellipodia nucleation by filopodia depends on integrin occupancy and downstream Rac1 signaling, Experimental Cell Research, vol.314, issue.3, pp.314478-488, 2008.
DOI : 10.1016/j.yexcr.2007.10.026

URL : https://hal.archives-ouvertes.fr/inserm-00263420

J. Han, C. J. Lim, N. Watanabe, A. Soriani, B. Ratnikov et al., Reconstructing and deconstructing agonist-induced activation of integrin alphaiibbeta3, Curr Biol, issue.18, pp.161796-1806, 2006.

H. Higgs and T. Pollard, of Wiskott-Aldrich Syndrome Protein (Wasp) Stimulates Actin Nucleation by Arp2/3 Complex, The Journal of Cell Biology, vol.90, issue.6, pp.1311-1320, 2000.
DOI : 10.1083/jcb.138.2.363

R. O. Hynes, Integrins, Cell, vol.110, issue.6, pp.673-687, 2002.
DOI : 10.1016/S0092-8674(02)00971-6

L. Ji, J. Lim, and G. Danuser, Fluctuations of intracellular forces during cell protrusion, Nature Cell Biology, vol.78, issue.12, pp.1393-1400, 2008.
DOI : 10.1038/sj.embor.7400105

L. Landau and E. Lifshitz, Theory of elasticity, 1970.

C. , L. Clainche, and M. Carlier, Regulation of actin assembly associated with protrusion and adhesion in cell migration, Physiol Rev, vol.88, issue.2, pp.489-513, 2008.

S. Li, P. Butler, Y. Wang, Y. Hu, D. C. Han et al., The role of the dynamics of focal adhesion kinase in the mechanotaxis of endothelial cells, Proceedings of the National Academy of Sciences, vol.99, issue.6, pp.993546-3551, 2002.
DOI : 10.1073/pnas.052018099

K. Ling, N. J. Schill, M. P. Wagoner, Y. Sun, and R. A. Anderson, Movin' on up: the role of PtdIns(4,5)P2 in cell migration, Trends in Cell Biology, vol.16, issue.6, pp.276-84, 2006.
DOI : 10.1016/j.tcb.2006.03.007

V. Martel, C. Racaud-sultan, S. Dupe, C. Marie, F. Paulhe et al., Albiges-Rizo. Conformation, localization, and integrin binding of talin depend on its interaction with phosphoinositides, J Biol Chem, issue.24, pp.27621217-21227, 2001.

A. Misra, R. P. Lim, Z. Wu, and T. Thanabalu, N-WASP plays a critical role in fibroblast adhesion and spreading, Biochemical and Biophysical Research Communications, vol.364, issue.4, pp.908-912, 2007.
DOI : 10.1016/j.bbrc.2007.10.086

A. Nicolas, A. Besser, and S. A. Safran, Dynamics of Cellular Focal Adhesions on Deformable Substrates: Consequences for Cell Force Microscopy, Biophysical Journal, vol.95, issue.2, pp.527-539, 2008.
DOI : 10.1529/biophysj.107.127399

URL : https://hal.archives-ouvertes.fr/hal-00394501

A. Nicolas, B. Geiger, and S. A. Safran, Cell mechanosensitivity controls the anisotropy of focal adhesions, Proceedings of the National Academy of Sciences, vol.101, issue.34, pp.12520-12525, 2004.
DOI : 10.1073/pnas.0403539101

M. J. Paszek, N. Zahir, K. R. Johnson, J. N. Lakins, G. I. Rozenberg et al., Tensional homeostasis and the malignant phenotype, Cancer Cell, vol.8, issue.3, pp.241-254, 2005.
DOI : 10.1016/j.ccr.2005.08.010

A. Pathak, V. S. Deshpande, R. M. Mcmeeking, and A. G. Evans, The simulation of stress fibre and focal adhesion development in cells on patterned substrates, Journal of The Royal Society Interface, vol.60, issue.1, pp.507-524, 2008.
DOI : 10.1002/cm.20041

A. Pierres, A. Benoliel, D. Touchard, and P. Bongrand, How Cells Tiptoe on Adhesive Surfaces before Sticking, Biophysical Journal, vol.94, issue.10, 2008.
DOI : 10.1529/biophysj.107.125278

URL : https://hal.archives-ouvertes.fr/hal-00317467

T. D. Pollard and G. Borisy, Cellular Motility Driven by Assembly and Disassembly of Actin Filaments, Cell, vol.112, issue.4, pp.453-465, 2003.
DOI : 10.1016/S0092-8674(03)00120-X

E. Puklin-faucher and M. P. Sheetz, The mechanical integrin cycle, Journal of Cell Science, vol.122, issue.2, pp.179-186, 2009.
DOI : 10.1242/jcs.042127

A. R. Reynolds, C. Tischer, P. J. Verveer, O. Rocks, and P. I. Bastiaens, EGFR activation coupled to inhibition of tyrosine phosphatases causes lateral signal propagation, Nature Cell Biology, vol.78, issue.5, pp.447-453, 2003.
DOI : 10.1038/ncb981

A. Scott, Nonlinear Science, Emergence and Dynamics of Coherence Structure, 1999.

S. J. Shattil, Integrins and Src: dynamic duo of adhesion signaling, Trends in Cell Biology, vol.15, issue.8, pp.399-403, 2005.
DOI : 10.1016/j.tcb.2005.06.005

C. Soulé, Mathematical approaches to differentiation and gene regulation, Comptes Rendus Biologies, vol.329, issue.1, pp.13-20
DOI : 10.1016/j.crvi.2005.10.002

S. Tadokoro, S. J. Shattil, K. Eto, V. Tai, R. C. Liddington et al., Talin binding to integrin beta tails: a final common step in integrin activation, Science, issue.5642, pp.302103-106, 2003.

T. Takenawa and S. Suetsugu, The WASP???WAVE protein network: connecting the membrane to the cytoskeleton, Nature Reviews Molecular Cell Biology, vol.45, issue.1, pp.37-48, 2007.
DOI : 10.1038/nrm2069

M. Thery, V. Racine, A. Pepin, M. Piel, Y. Chen et al., The extracellular matrix guides the orientation of the cell division axis, Nature Cell Biology, vol.124, issue.10, pp.7-1465, 2005.
DOI : 10.1007/s00249-003-0282-2

S. Tsuboi, S. Nonoyama, and H. D. Ochs, Wiskott-aldrich syndrome protein is involved in alphaiib beta3-mediated cell adhesion, EMBO Rep, vol.7, issue.5, pp.506-511, 2006.
DOI : 10.1038/sj.embor.7400665

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1479562

P. J. Verveer, F. S. Wouters, A. R. Reynolds, and P. I. Bastiaens, Quantitative Imaging of Lateral ErbB1 Receptor Signal Propagation in the Plasma Membrane, Science, vol.290, issue.5496, pp.2901567-1570, 2000.
DOI : 10.1126/science.290.5496.1567

M. Vicente-manzanares, C. K. Choi, and A. R. Horwitz, Integrins in cell migration - the actin connection, Journal of Cell Science, vol.122, issue.2, pp.199-206, 2009.
DOI : 10.1242/jcs.018564

V. Vogel and M. Sheetz, Local force and geometry sensing regulate cell functions, Nature Reviews Molecular Cell Biology, vol.31, issue.4, pp.265-275, 2006.
DOI : 10.1016/S0022-2836(02)01001-X

Y. Wang, E. L. Botvinick, Y. Zhao, M. W. Berns, S. Usami et al., Visualizing the mechanical activation of Src, Nature, vol.9, issue.7036, pp.4341040-1045, 2005.
DOI : 10.1016/S0960-9822(01)00583-8

W. W. Webb, L. S. Barak, D. W. Tank, and E. S. Wu, Molecular mobility on the cell surface, Biochem Soc Symp, issue.46, pp.191-205, 1981.

J. P. Xiong, T. Stehle, B. Diefenbach, R. Zhang, R. Dunker et al., Crystal structure of the extracellular segment of integrin alpha vbeta3, Science, issue.5541, pp.294339-345, 2001.

X. Zhang, G. Jiang, Y. Cai, S. Monkley, D. Critchley et al., Talin depletion reveals independence of initial cell spreading from integrin activation and traction, Nature Cell Biology, vol.86, issue.9, 2008.
DOI : 10.1126/science.1135085