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[Epileptic seizure and migraine visual aura: revisiting migralepsy]

Abstract : INTRODUCTION: The term of "migralepsy" has been proposed to define migraine-triggered epileptic seizures. Although already reported in the literature for more than fifty years, a number of observations remain debatable because of possible confusion between migraine and epileptic seizure clinical manifestations, including hemifield visual hallucinations, digestive signs and severe headache. OBSERVATION: We report on the case of a young patient suffering from both diseases, in whom a visual aura preceded either migraine attacks or epileptic generalized tonic-clonic seizure. Subtle modification in the primitive visual hallucination, which suddenly contained colored figures and was accompanied by fear before a prolonged loss of contact, suggested a continuum between migraine aura and epileptic seizure in this patient. Brain MRI was normal and EEG showed some sharp waves in the right posterior area. CONCLUSION: The presence of a neurophysiological continuum between migrainous aura and epileptic seizure is supported by this observation of "migralepsy". Recent findings from genetic and epidemiological studies further support this link.
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https://www.hal.inserm.fr/inserm-00410597
Contributor : Colin Deransart <>
Submitted on : Friday, August 21, 2009 - 3:29:03 PM
Last modification on : Thursday, September 3, 2009 - 2:33:45 PM

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Marie Barré, S. Hamelin, Lorella Minotti, Philippe Kahane, Laurent Vercueil. [Epileptic seizure and migraine visual aura: revisiting migralepsy]. Revue Neurologique, Elsevier Masson, 2008, 164 (3), pp.246-52. ⟨10.1016/j.neurol.2007.10.007⟩. ⟨inserm-00410597⟩

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