P. Coumel, J. Fidelle, V. Lucet, P. Attuel, and Y. Bouvrain, Catecholamineinduced severe ventricular arrhythmias with Adams-Stokes syndrome in children: report of four cases, Br Heart J, vol.40, pp.28-37, 1978.

A. Leenhardt, V. Lucet, I. Denjoy, F. Grau, D. Ngoc et al., Catecholaminergic Polymorphic Ventricular Tachycardia in Children : A 7-Year Follow-up of 21 Patients, Circulation, vol.91, issue.5, pp.1512-1519, 1995.
DOI : 10.1161/01.CIR.91.5.1512

P. Laitinen, K. Brown, K. Piippo, H. Swan, J. Devaney et al., Mutations of the Cardiac Ryanodine Receptor (RyR2) Gene in Familial Polymorphic Ventricular Tachycardia, Circulation, vol.103, issue.4, pp.485-490, 2001.
DOI : 10.1161/01.CIR.103.4.485

S. Priori, C. Napolitano, N. Tiso, M. Memmi, G. Vignati et al., Mutations in the Cardiac Ryanodine Receptor Gene (hRyR2) Underlie Catecholaminergic Polymorphic Ventricular Tachycardia, Circulation, vol.103, issue.2, pp.196-200, 2001.
DOI : 10.1161/01.CIR.103.2.196

H. Lahat, E. Pras, T. Olender, N. Avidan, B. Asher et al., A Missense Mutation in a Highly Conserved Region of CASQ2 Is Associated with Autosomal Recessive Catecholamine-Induced Polymorphic Ventricular Tachycardia in Bedouin Families from Israel, The American Journal of Human Genetics, vol.69, issue.6, pp.1378-1384, 2001.
DOI : 10.1086/324565

A. Postma, I. Denjoy, T. Hoorntje, J. Lupoglazoff, D. Costa et al., Absence of Calsequestrin 2 Causes Severe Forms of Catecholaminergic Polymorphic Ventricular Tachycardia, Circulation Research, vol.91, issue.8, pp.21-26, 2002.
DOI : 10.1161/01.RES.0000038886.18992.6B

G. Choi, L. Kopplin, D. Tester, M. Will, C. Haglund et al., Spectrum and Frequency of Cardiac Channel Defects in Swimming-Triggered Arrhythmia Syndromes, Circulation, vol.110, issue.15, pp.2119-2124, 2004.
DOI : 10.1161/01.CIR.0000144471.98080.CA

D. Tester, L. Kopplin, M. Will, and M. Ackerman, Spectrum and prevalence of cardiac ryanodine receptor (RyR2) mutations in a cohort of unrelated patients referred explicitly for long QT syndrome genetic testing, Heart Rhythm, vol.2, issue.10, pp.1099-1105, 2005.
DOI : 10.1016/j.hrthm.2005.07.012

B. Bauce, A. Rampazzo, C. Basso, A. Bagattin, L. Daliento et al., Screening for ryanodine receptor type 2 mutations in families with effort-induced polymorphic ventricular arrhythmias and sudden death, Journal of the American College of Cardiology, vol.40, issue.2, pp.341-349, 2002.
DOI : 10.1016/S0735-1097(02)01946-0

H. Lahat, M. Eldar, E. Levy-nissenbaum, T. Bahan, E. Friedman et al., Autosomal Recessive Catecholamine- or Exercise-Induced Polymorphic Ventricular Tachycardia : Clinical Features and Assignment of the Disease Gene to Chromosome 1p13-21, Circulation, vol.103, issue.23, pp.2822-2827, 2001.
DOI : 10.1161/01.CIR.103.23.2822

A. Postma, I. Denjoy, J. Kamblock, M. Alders, J. Lupoglazoff et al., Catecholaminergic polymorphic ventricular tachycardia: RYR2 mutations, bradycardia, and follow up of the patients, Journal of Medical Genetics, vol.42, issue.11, pp.863-870, 2005.
DOI : 10.1136/jmg.2004.028993

S. Priori, C. Napolitano, M. Memmi, B. Colombi, F. Drago et al., Clinical and Molecular Characterization of Patients With Catecholaminergic Polymorphic Ventricular Tachycardia, Circulation, vol.106, issue.1, pp.69-74, 2002.
DOI : 10.1161/01.CIR.0000020013.73106.D8

N. Sumitomo, K. Harada, M. Nagashima, T. Yasuda, Y. Nakamura et al., Catecholaminergic polymorphic ventricular tachycardia: electrocardiographic characteristics and optimal therapeutic strategies to prevent sudden death, Heart, vol.89, issue.1, pp.66-70, 2003.
DOI : 10.1136/heart.89.1.66

URL : http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1767500

H. Swan, K. Piippo, M. Viitasalo, P. Heikkila, T. Paavonen et al., Arrhythmic disorder mapped to chromosome 1q42???q43 causes malignant polymorphic ventricular tachycardia in structurally normal hearts, Journal of the American College of Cardiology, vol.34, issue.7, pp.2035-2042, 1999.
DOI : 10.1016/S0735-1097(99)00461-1

B. Maron, B. Chaitman, M. Ackerman, . Bayes-de-luna, D. Corrado et al., Recommendations for Physical Activity and Recreational Sports Participation for Young Patients With Genetic Cardiovascular Diseases, Circulation, vol.109, issue.22, pp.2807-2816, 2004.
DOI : 10.1161/01.CIR.0000128363.85581.E1

E. Kaplan and P. Meier, Nonparametric Estimation from Incomplete Observations, Journal of the American Statistical Association, vol.37, issue.282, pp.457-481, 1958.
DOI : 10.1214/aoms/1177731566

D. Cox, Regression models and lifetables, J R Stat Soc (B), vol.34, pp.187-220, 1972.

R. Rosso, J. Kalman, O. Rogowski, S. Diamant, A. Birger et al., Calcium channel blockers and beta-blockers versus beta-blockers alone for preventing exercise-induced arrhythmias in catecholaminergic polymorphic ventricular tachycardia, Heart Rhythm, vol.4, issue.9, pp.1149-1154, 2007.
DOI : 10.1016/j.hrthm.2007.05.017

H. Swan, P. Laitinen, K. Kontula, and L. Toivonen, Calcium Channel Antagonism Reduces Exercise-Induced Ventricular Arrhythmias in Catecholaminergic Polymorphic Ventricular Tachycardia Patients with RyR2 Mutations, Journal of Cardiovascular Electrophysiology, vol.193, issue.2, pp.162-166, 2005.
DOI : 10.1016/S0002-9149(96)00011-2