Synthesis and biological evaluation of conformationally constrained analogues of the antitubercular agent ethambutol. - Archive ouverte HAL Access content directly
Journal Articles Bioorganic and Medicinal Chemistry Year : 2007

Synthesis and biological evaluation of conformationally constrained analogues of the antitubercular agent ethambutol.

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Abstract

Three (S)-prolinol-derived conformationally restricted analogues of the antitubercular agent ethambutol were prepared and tested against Mycobacterium tuberculosis.

Dates and versions

inserm-00409609 , version 1 (11-08-2009)

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Vanessa Faugeroux, Yves Génisson, Yahya Salma, Patricia Constant, Michel Baltas. Synthesis and biological evaluation of conformationally constrained analogues of the antitubercular agent ethambutol.. Bioorganic and Medicinal Chemistry, 2007, 15 (17), pp.5866-76. ⟨10.1016/j.bmc.2007.05.064⟩. ⟨inserm-00409609⟩
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