J. Ms#-200901040r2, Online Supplemental material S1: Characterization of HUES-9 pOct4/GFP clone. Non-cardiac potential of differentiation of Oct4-OEC

. Sox2, Sox17 and consequences on BMP2-induced gene expression S2: Paracrine action of Oct4-overexpressing cells S3: Oct4 overexpressing cells activate smad and ?-catenin pathways; The Oct4

D. We and H. Ng, Genome Institute of Singapore) for the gift of Sox2 ShRNA plasmid, Drs M Mitjavila and N Lefort for help in FACS analysis, Y Maury (INSERM-UMR861) for help in HC imaging

R. Singapore, . Feil, and . Montpellier, France) for critical reading of the MS, Dr M. Buckingham (Pasteur Institute, Paris) for her invaluable comments on the MS the National Agency for Research (ANR, programmes Blanc, HUES signature and Specistem) and Genopole for funding this research. SS and DN were funded by ANR, p.18

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