Orexins (hypocretins) directly excite tuberomammillary neurons, European Journal of Neuroscience, vol.901, issue.9, pp.1571-1575, 2001. ,
DOI : 10.1046/j.0953-816x.2001.01777.x
Convergent excitation of dorsal raphe serotonin neurons by multiple arousal systems (orexin/hypocretin, histamine, and noradrenaline), J Neurosci, vol.22, pp.8850-8859, 2002. ,
Narcolepsy in orexin Knockout Mice, Cell, vol.98, issue.4, pp.437-451, 1999. ,
DOI : 10.1016/S0092-8674(00)81973-X
Voltage clamp studies of a transient outward membrane current in gastropod neural somata, The Journal of Physiology, vol.213, issue.1, pp.21-30, 1971. ,
DOI : 10.1113/jphysiol.1971.sp009365
Effects of microdialysis application of monoamines on the EEG and behavioural states in the cat mesopontine tegmentum, European Journal of Neuroscience, vol.24, issue.10, pp.3738-3752, 1999. ,
DOI : 10.1016/0006-8993(88)90471-4
Morphological analysis of the tuberomammmillary nucleus in the rat brain: Delineation of subgroups with antibody again L-histidine decarboxylase as a marker, Journal of Comparative Neurology, vol.4, issue.1, pp.1-24, 1987. ,
DOI : 10.1002/cne.902630102
Orexin/hypocretin excites the histaminergic neurons of the tuberomammillary nucleus, J Neurosci, vol.21, pp.9273-9279, 2001. ,
Two transient outward currents in histamine neurones of the rat hypothalamus in vitro., The Journal of Physiology, vol.420, issue.1, pp.149-163, 1990. ,
DOI : 10.1113/jphysiol.1990.sp017905
The role of histamine and the tuberomamillary nucleus in the nervous system, Nature Reviews Neuroscience, vol.346, issue.2, pp.121-130, 2003. ,
DOI : 10.1038/nrn1034
Electrophysiology of histamine receptors In: The histamine receptor, pp.161-177, 1992. ,
Membrane properties of histaminergic tuberomammillary neurones of the rat hypothalamus in vitro., The Journal of Physiology, vol.399, issue.1, pp.633-646, 1988. ,
DOI : 10.1113/jphysiol.1988.sp017100
Orexin A promotes histamine, but not norepinephrine or serotonin, release in frontal cortex of mice1, Acta Pharmacologica Sinica, vol.23, issue.2, pp.155-159, 2005. ,
DOI : 10.1016/S0896-6273(04)00247-8
Arousal effect of orexin A depends on activation of the histaminergic system, Proceedings of the National Academy of Sciences, vol.98, issue.17, pp.9965-9970, 2001. ,
DOI : 10.1073/pnas.181330998
Organization of histaminergic fibers in the rat brain, The Journal of Comparative Neurology, vol.35, issue.3, pp.283-300, 1988. ,
DOI : 10.1002/cne.902730302
Cataplexy-Active Neurons in the Hypothalamus, Neuron, vol.42, issue.4, pp.619-634, 2004. ,
DOI : 10.1016/S0896-6273(04)00247-8
Basic Mechanisms of Sleep-Wake States, pp.136-153, 2005. ,
DOI : 10.1016/B0-72-160797-7/50018-5
Hyperpolarization-activated inward current in histaminergic tuberomammillary neurons of the rat hypothalamus, J Neurophysiol, vol.66, pp.1902-1911, 1991. ,
Cholinergic nucleus basalis neurons are excited by histamine in vitro, Neuroscience, vol.69, issue.2, pp.495-506, 1995. ,
DOI : 10.1016/0306-4522(95)00264-J
Modulation of presumed cholinergic mesopontine tegmental neurons by acetylcholine and monoamines applied iontophoretically in unanesthetized cats, Neuroscience, vol.96, issue.4, pp.723-733, 2000. ,
DOI : 10.1016/S0306-4522(00)00004-X
PHYSIOLOGICAL REVIEW ARTICLE: Brain structures and mechanisms involved in the control of cortical activation and wakefulness, with emphasis on the posterior hypothalamus and histaminergic neurons, Sleep Medicine Reviews, vol.4, issue.5, pp.471-503, 2000. ,
DOI : 10.1053/smrv.2000.0116
A critical role of the posterior hypothalamus in the mechanisms of wakefulness determined by microinjection of muscimol in freely moving cats, Brain Research, vol.479, issue.2, pp.225-240, 1989. ,
DOI : 10.1016/0006-8993(89)91623-5
Histaminergic descending inputs to the mesopontine tegmentum and their role in the control of cortical activation and wakefulness in the cat, J Neurosci, vol.16, pp.1523-1537, 1996. ,
The Sleep Disorder Canine Narcolepsy Is Caused by a Mutation in the Hypocretin (Orexin) Receptor 2 Gene, Cell, vol.98, issue.3, pp.365-376, 1999. ,
DOI : 10.1016/S0092-8674(00)81965-0
Electrophysiology of the mammillary complex in vitro. I. Tuberomammillary and lateral mammillary neurons, J Neurophysiol, vol.68, pp.1307-1320, 1992. ,
Convergence and divergence of neurotransmitter action in human cerebral cortex., Proceedings of the National Academy of Sciences, vol.86, issue.20, pp.8098-8102, 1989. ,
DOI : 10.1073/pnas.86.20.8098
Modulation of neuronal firing mode in cat and guinea pig LGNd by histamine: possible cellular mechanisms of histaminergic control of arousal, J Neurosci, vol.11, pp.3188-3199, 1991. ,
The sleep-waking cycle, Ergeb Physiol, vol.64, pp.1-165, 1972. ,
ANTIHISTAMINES AND SEDATION, The Lancet, vol.322, issue.8343, pp.211-212, 1983. ,
DOI : 10.1016/S0140-6736(83)90185-X
Anatomical, physiological, and pharmacological characteristics of histidine decarboxylase knock-out mice: evidence for the role of brain histamine in behavioral and sleep-wake control, J Neurosci, vol.22, pp.7695-7711, 2002. ,
A mutation in a case of early onset narcolepsy and a generalized absence of hypocretin peptides in human narcoleptic brains, Nat Med, vol.6, pp.991-997, 2000. ,
A novel single-cell staining procedure performed in vivo under electrophysiological control: morpho-functional features of juxtacellularly labeled thalamic cells and other central neurons with biocytin or Neurobiotin, Journal of Neuroscience Methods, vol.65, issue.2, pp.113-136, 1996. ,
DOI : 10.1016/0165-0270(95)00144-1
Mechanisms of antihistamine-induced sedation in the human brain: H1 receptor activation reduces a background leakage potassium current, Neuroscience, vol.59, issue.3, pp.579-588, 1994. ,
DOI : 10.1016/0306-4522(94)90178-3
Electrophysiological properties of cortically projecting histamine neurons of the rat hypothalamus, Neuroscience Letters, vol.73, issue.1, pp.43-47, 1987. ,
DOI : 10.1016/0304-3940(87)90028-0
Serotonergic dorsal raphe neurons cease firing by disfacilitation during paradoxical sleep, NeuroReport, vol.11, issue.14, pp.3237-3241, 2000. ,
DOI : 10.1097/00001756-200009280-00037
The posterior hypothalamus in the regulation of wakefulness, and paradoxical sleep, The diencephalon and sleep (Mancia M, Marini M, pp.171-198, 1990. ,
The sleep switch: hypothalamic control of sleep and wakefulness, Trends in Neurosciences, vol.24, issue.12, pp.726-731, 2001. ,
DOI : 10.1016/S0166-2236(00)02002-6
Histaminergic transmission in the mammalian brain, Physiol Rev, vol.71, pp.1-51, 1991. ,
Sleep???waking discharge of neurons in the posterior lateral hypothalamus of the albino rat, Brain Research, vol.840, issue.1-2, pp.138-147, 1999. ,
DOI : 10.1016/S0006-8993(99)01648-0
Calcium-dependent prepotentials contribute to spontaneous activity in rat tuberomammillary neurons., The Journal of Physiology, vol.493, issue.3, pp.747-754, 1996. ,
DOI : 10.1113/jphysiol.1996.sp021419
The mechanism of spontaneous firing in histamine neurons, Behavioural Brain Research, vol.124, issue.2, pp.105-112, 2001. ,
DOI : 10.1016/S0166-4328(01)00219-4
Waking-statespecific neurons in the posterior hypothalamus of the cat, Sleep, vol.84, pp.238-240, 1985. ,
Is the histaminergic neuron system a regulatory center for whole-brain activity?, Trends in Neurosciences, vol.14, issue.9, pp.415-418, 1991. ,
DOI : 10.1016/0166-2236(91)90034-R
Orexins Activate Histaminergic Neurons via the Orexin 2 Receptor, Biochemical and Biophysical Research Communications, vol.290, issue.4, pp.1237-1245, 2002. ,
DOI : 10.1006/bbrc.2001.6318
Electrophysiology of excitatory and inhibitory afferents to rat histaminergic tuberomammillary nucleus neurons from hypothalamic and forebrain sites, Brain Research, vol.773, issue.1-2, pp.162-172, 1997. ,
DOI : 10.1016/S0006-8993(97)00932-3