Abstract : Hepatitis C virus (HCV) is a major cause of posttransfusion and community-acquired hepatitis in the world [1]. The majority of HCV-infected individuals develop chronic hepatitis that may progress to liver cirrhosis and hepatocellular carcinoma. Treatment options for chronic HCV infection are limited and a vaccine to prevent HCV infection is not available [1]. The development of efficient antivirals and a vaccine has been hampered by the lack of an efficient tissue culture model for HCV infection.
http://www.hal.inserm.fr/inserm-00395790
Contributeur : Thomas Baumert
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Soumis le : mardi 16 juin 2009 - 14:13:14
Dernière modification le : jeudi 18 juin 2009 - 11:49:49
Document(s) archivé(s) le : jeudi 10 juin 2010 - 21:04:05
Mirjam Zeisel, Thomas Baumert. Production of infectious hepatitis C virus in tissue culture: a breakthrough for basic and applied research.. Journal of Hepatology, Elsevier, 2006, 44 (2), pp.436-9. 〈10.1016/j.jhep.2005.11.031〉. 〈inserm-00395790〉
