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Production of infectious hepatitis C virus in tissue culture: a breakthrough for basic and applied research.

Mirjam B. Zeisel 1 Thomas F. Baumert 1, * 
* Corresponding author
Abstract : Hepatitis C virus (HCV) is a major cause of posttransfusion and community-acquired hepatitis in the world [1]. The majority of HCV-infected individuals develop chronic hepatitis that may progress to liver cirrhosis and hepatocellular carcinoma. Treatment options for chronic HCV infection are limited and a vaccine to prevent HCV infection is not available [1]. The development of efficient antivirals and a vaccine has been hampered by the lack of an efficient tissue culture model for HCV infection.
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https://www.hal.inserm.fr/inserm-00395790
Contributor : Thomas F. Baumert Connect in order to contact the contributor
Submitted on : Tuesday, June 16, 2009 - 2:13:14 PM
Last modification on : Thursday, November 26, 2020 - 3:56:04 PM
Long-term archiving on: : Thursday, June 10, 2010 - 9:04:05 PM

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Mirjam B. Zeisel, Thomas F. Baumert. Production of infectious hepatitis C virus in tissue culture: a breakthrough for basic and applied research.. Journal of Hepatology, Elsevier, 2006, 44 (2), pp.436-9. ⟨10.1016/j.jhep.2005.11.031⟩. ⟨inserm-00395790⟩

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