Newest aspects on the association between migraine and cardiovascular disease: the role of modifying factors. - Archive ouverte HAL Access content directly
Journal Articles Current Pain and Headache Reports Year : 2009

Newest aspects on the association between migraine and cardiovascular disease: the role of modifying factors.

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Tobias Kurth
  • Function : Correspondent author
  • PersonId : 860624

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Abstract

Migraine has been established as a risk factor for ische-mic stroke. Further evidence suggests that migraine is also associated with other ischemic vascular events, including myocardial infarction and cardiovascular death. However, these associations appear to be limited to the subgroup of patients with migraine with aura (MA). Moreover, there is increasing evidence that among patients with MA, additional subgroups exist that carry particular increased risk. The association with ischemic stroke is, for example, particularly strong for younger women with MA who smoke and/or use oral contraceptives. Results from recent studies support an even more complex interrelationship characterized by additional modifying effects of other factors on the association between MA and ischemic vascular events. These include vascular risk factors, migraine attack frequency, and genetic variants. In addition, there appear to be differential effects with regard to ischemic stroke and myocardial infarction. These new findings await confirmation in independent patient populations and are currently not sufficient to argue for a change in diagnostic testing or treatment.
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Dates and versions

inserm-00388056 , version 1 (26-05-2009)

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  • HAL Id : inserm-00388056 , version 1
  • PUBMED : 19457285

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Tobias Kurth, Markus Schürks. Newest aspects on the association between migraine and cardiovascular disease: the role of modifying factors.. Current Pain and Headache Reports, 2009, 13 (3), pp.231-6. ⟨inserm-00388056⟩
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