Correlation between the anatomical and functional human subthalamic nucleus. - Archive ouverte HAL Access content directly
Journal Articles Stereotactic and Functional Neurosurgery Year : 2007

Correlation between the anatomical and functional human subthalamic nucleus.

(1) , (1) , (1) , (2)
1
2

Abstract

This work addresses the spatial correlation between the anatomical and functional human subthalamic nucleus (STN). The anatomical STN (A-STN), derived from the Schaltenbrand-Wahren brain atlas, is histology based. The functional STN (F-STN) is probabilistic, constructed from neuroelectrophysiological and neuroimaging data of 184 Parkinson's disease patients. The A-STN and F-STN are placed in the same space and compared in terms of mutual relative overlapping of anatomy with function. The F-STN and A-STN correlate well for medium and high probabilities of the F-STN. For probability p >or= 0.3, >95% of F-STN is inside the A-STN, and for p >or= 0.5, the complete F-STN is inside the A-STN for each left and right STN. Therefore, the F-STN for p = 0.5 can potentially be used for identification of the STN in neuroimages.
Not file

Dates and versions

inserm-00382760 , version 1 (11-05-2009)

Identifiers

Cite

Wieslaw L. Nowinski, A. Thirunavuukarasuu, Jimin Liu, Alim-Louis Benabid. Correlation between the anatomical and functional human subthalamic nucleus.. Stereotactic and Functional Neurosurgery, 2007, 85 (2-3), pp.88-93. ⟨10.1159/000097924⟩. ⟨inserm-00382760⟩

Collections

INSERM UGA
31 View
0 Download

Altmetric

Share

Gmail Facebook Twitter LinkedIn More