I. Klatzo, Pathophysiological aspects of brain edema, Acta Neuropathologica, vol.66, issue.3, pp.236-239, 1987.
DOI : 10.1007/BF00691095

D. M. Hermann, E. Kilic, A. Spudich, S. D. Kramer, H. Wunderli-allenspach et al., Role of drug efflux carriers in the healthy and diseased brain, Annals of Neurology, vol.316, issue.5, pp.489-498, 2006.
DOI : 10.1002/ana.21012

W. M. Pardridge, Blood-brain barrier biology and methodology, Journal of Neurovirology, vol.5, issue.6, pp.556-569, 1999.
DOI : 10.3109/13550289909021285

E. Oby and D. Janigro, The Blood?Brain Barrier and Epilepsy, Epilepsia, vol.16, issue.7, pp.1761-1774, 2006.
DOI : 10.1007/s002210050759

M. H. Sarker, D. E. Hu, and P. A. Fraser, Acute effects of bradykinin on cerebral microvascular permeability in the anaesthetized rat, The Journal of Physiology, vol.70, issue.1, pp.177-187, 2000.
DOI : 10.1111/j.1469-7793.2000.00177.x

M. A. Petty and E. H. Lo, Junctional complexes of the blood???brain barrier: permeability changes in neuroinflammation, Progress in Neurobiology, vol.68, issue.5, pp.311-323, 2002.
DOI : 10.1016/S0301-0082(02)00128-4

C. S. Patlak, R. G. Blasberg, and J. D. Fenstermacher, Graphical Evaluation of Blood-to-Brain Transfer Constants from Multiple-Time Uptake Data, Journal of Cerebral Blood Flow & Metabolism, vol.84, issue.1, pp.1-7, 1983.
DOI : 10.1111/j.1471-4159.1977.tb10649.x

B. T. Hawkins and R. D. Egleton, Fluorescence imaging of blood???brain barrier disruption, Journal of Neuroscience Methods, vol.151, issue.2, pp.262-267, 2006.
DOI : 10.1016/j.jneumeth.2005.08.006

R. Sood, S. Taheri, E. Y. Estrada, and G. A. Rosenberg, Quantitative evaluation of the effect of propylene glycol on BBB permeability, Journal of Magnetic Resonance Imaging, vol.26, issue.1, pp.39-47, 2007.
DOI : 10.1002/jmri.20802

S. Taheri and R. Sood, Kalman filtering for reliable estimation of BBB permeability, Magnetic Resonance Imaging, vol.24, issue.8, pp.1039-1049, 2006.
DOI : 10.1016/j.mri.2006.07.002

S. Syvanen, G. Blomquist, L. Appel, M. Hammarlund-udenaes, B. Langstrom et al., Predicting brain concentrations of drug using positron emission tomography and venous input: modeling of arterial-venous concentration differences, European Journal of Clinical Pharmacology, vol.284, issue.10, pp.839-848, 2006.
DOI : 10.1007/s00228-006-0179-y

N. Z. Wu, B. Klitzman, G. Rosner, D. Needham, and M. W. Dewhirst, Measurement of Material Extravasation in Microvascular Networks Using Fluorescence Video-Microscopy, Microvascular Research, vol.46, issue.2, pp.231-253, 1993.
DOI : 10.1006/mvre.1993.1049

A. Bultmann, L. Schilling, A. Findling, and M. Wahl, Investigation of blood-brain barrier permeability by means of computerized image analysis, Vasa, vol.23, pp.195-204, 1994.

J. Takahashi, F. Mori, T. Hikichi, and A. Yoshida, Effect of acetazolamide on outward permeability of blood-retina barrier using differential vitreous flyorophotometry, Current Eye Research, vol.25, issue.3, pp.166-170, 2001.
DOI : 10.1076/ceyr.23.3.166.5461

W. Denk, J. H. Strickler, and W. W. Webb, Two-photon laser scanning fluorescence microscopy, Science, vol.248, issue.4951, pp.73-76, 1990.
DOI : 10.1126/science.2321027

D. Kleinfeld, P. P. Mitra, F. Helmchen, and W. Denk, Fluctuations and stimulus-induced changes in blood flow observed in individual capillaries in layers 2 through 4 of rat neocortex, Proceedings of the National Academy of Sciences, vol.95, issue.26, pp.15741-15746, 1998.
DOI : 10.1073/pnas.95.26.15741

. Vérant, Subtraction method for intravital two-photon microscopy?, Journal of Biomedical Optics, vol.131, pp.11002-11012, 2008.

R. Serduc, P. Vérant, J. C. Vial, R. Farion, L. Rocas et al., In vivo two-photon microscopy study of short-term effects of microbeam irradiation on normal mouse brain microvasculature, International Journal of Radiation Oncology*Biology*Physics, vol.64, issue.5, pp.1519-1527, 2006.
DOI : 10.1016/j.ijrobp.2005.11.047

URL : https://hal.archives-ouvertes.fr/inserm-00388979

J. A. Laissue, G. Geiser, P. O. Spanne, F. A. Dilmanian, J. O. Gebbers et al., Neuropathology of ablation of rat gliosarcomas and contiguous brain tissues using a microplanar beam of synchrotron-wiggler-generated X rays, International Journal of Cancer, vol.14, issue.5, pp.654-660, 1998.
DOI : 10.1002/(SICI)1097-0215(19981123)78:5<654::AID-IJC21>3.0.CO;2-L

P. Vérant, to be published, and P. Vérant, Thesis in Physical Sciences, 2006.

H. F. Cserr, M. Depasquale, C. S. Patlak, and R. G. Pullen, Convection of Cerebral Interstitial Fluid and Its Role in Brain Volume Regulation, Annals of the New York Academy of Sciences, vol.238, issue.1 The Neuronal, pp.123-133, 1987.
DOI : 10.1016/0014-4886(74)90099-5

P. Vérant, R. Serduc, B. Van-der-sanden, C. Remy, and J. C. Vial, A Direct Method for Measuring Mouse Capillary Cortical Blood Volume Using Multiphoton Laser Scanning Microscopy, Journal of Cerebral Blood Flow & Metabolism, vol.36, issue.5, pp.1072-1081, 2007.
DOI : 10.1371/journal.pbio.0040022

C. Xu and W. W. Webb, Measurement of two-photon excitation cross sections of molecular fluorophores with data from 690 to 1050 nm, Journal of the Optical Society of America B, vol.13, issue.3, pp.481-491, 1996.
DOI : 10.1364/JOSAB.13.000481

J. Vogel, I. Kiessling, K. Heinicke, T. Stallmach, P. Ossent et al., Transgenic mice overexpressing erythropoietin adapt to excessive erythrocytosis by regulating blood viscosity, Blood, vol.102, issue.6, pp.2278-2284, 2003.
DOI : 10.1182/blood-2003-01-0283

E. M. Robbins, R. A. Betensky, S. B. Domnitz, S. M. Purcell, M. Garcia-alloza et al., Kinetics of Cerebral Amyloid Angiopathy Progression in a Transgenic Mouse Model of Alzheimer Disease, Journal of Neuroscience, vol.26, issue.2, pp.365-371, 2006.
DOI : 10.1523/JNEUROSCI.3854-05.2006

A. Nimmerjahn, F. Kirchhoff, J. N. Kerr, and F. Helmchen, Sulforhodamine 101 as a specific marker of astroglia in the neocortex in vivo, Nature Methods, vol.263, issue.1, pp.31-37, 2004.
DOI : 10.1038/nmeth706

P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. Mcmahon et al., New Colorimetric Cytotoxicity Assay for Anticancer-Drug Screening, JNCI Journal of the National Cancer Institute, vol.82, issue.13, pp.1107-1112, 1990.
DOI : 10.1093/jnci/82.13.1107

G. Bouffard, Injection des couleurs de benzidine aux animaux normaux, Ann. Inst. Pasteur (Paris), vol.20, issue.539, p.1906

K. W. Dunn, R. M. Sandoval, K. J. Kelly, P. C. Dagher, G. A. Tanner et al., Functional studies of the kidney of living animals using multicolor two-photon microscopy, AJP: Cell Physiology, vol.283, issue.3, pp.905-916, 2002.
DOI : 10.1152/ajpcell.00159.2002

C. Nicholson, Diffusion and related transport mechanisms in brain tissue, Reports on Progress in Physics, vol.64, issue.7, pp.815-884, 2001.
DOI : 10.1088/0034-4885/64/7/202

A. K. Majewska, J. R. Newton, and M. Sur, Remodeling of Synaptic Structure in Sensory Cortical Areas In Vivo, Journal of Neuroscience, vol.26, issue.11, pp.3021-3029, 2006.
DOI : 10.1523/JNEUROSCI.4454-05.2006

. Vérant, Subtraction method for intravital two-photon microscopy?, Journal of Biomedical Optics, vol.131, pp.11002-11013, 2008.