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Article Dans Une Revue Schizophrenia Research Année : 2007

Does hyperpriming reveal impaired spreading of activation in schizophrenia?

Résumé

Enhancement of semantic priming effects (hyperpriming) has been well documented in schizophrenic patients (Minzenberg et al. 2002). In a previous study, we demonstrated that hyperpriming was related to a more pronounced requirement to inhibit unrelated information (Lecardeur et al. 2007). On the other hand, several authors have suggested that hyperpriming could reflect enhanced spreading of semantic activation in schizophrenia (Spitzer et al. 1993; Spitzer 1997; Moritz et al. 2001). So far, there are few reports that attempted to study the spreading of activation in schizophrenic patients compared to healthy controls, when the links between semantically related information were manipulated. Notably, authors stated that activation could consequently spread farther and further in the semantic networks of schizophrenic patients. Moreover, enhanced spreading of activation was hypothesized to be responsible of the appearance of thought and language disorders in schizophrenic patients. Consequently, we examined whether the manipulation of the type of connection and the semantic distance between prime and target can modulate semantic priming effects in schizophrenic patients compared to healthy controls.
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Dates et versions

inserm-00379465 , version 1 (28-04-2009)

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Laurent Lecardeur, Bénédicte Giffard, Mickael Laisney, Perrine Brazo, Emmanuel Stip, et al.. Does hyperpriming reveal impaired spreading of activation in schizophrenia?. Schizophrenia Research, 2007, 97 (1-3), pp.289-91. ⟨10.1016/j.schres.2007.08.017⟩. ⟨inserm-00379465⟩
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