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Transient MR elastography (t-MRE) using ultrasound radiation force: theory, safety, and initial experiments in vitro.

Abstract : The purpose of our study was to assess the feasibility of using ultrasound radiation force as a safe vibration source for transient MR elastography (t-MRE). We present a theoretical framework to predict the phase shift of the complex MRE signal, the temperature elevation due to ultrasound, and safety indicators (I(SPPA), I(SPTA), MI). Next, we report wave images acquired in porcine liver samples in vitro. MR thermometry was used to estimate the temperature elevation induced by ultrasound. Finally, we discuss the implications of our results with regard to the feasibility of using radiation force for t-MRE in a clinical setting, and a specific echo-planar imaging (EPI) MRE sequence is proposed.
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https://www.hal.inserm.fr/inserm-00376154
Contributor : Rémi Souchon <>
Submitted on : Thursday, April 16, 2009 - 5:43:39 PM
Last modification on : Monday, October 26, 2020 - 4:34:07 PM
Long-term archiving on: : Wednesday, March 29, 2017 - 4:32:21 PM

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Rémi Souchon, Rares Salomir, Olivier Beuf, Laurent Milot, Denis Grenier, et al.. Transient MR elastography (t-MRE) using ultrasound radiation force: theory, safety, and initial experiments in vitro.. Magnetic Resonance in Medicine, Wiley, 2008, 60 (4), pp.871-81. ⟨10.1002/mrm.21718⟩. ⟨inserm-00376154⟩

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