The tubulin fraternity: alpha to eta, Current Opinion in Cell Biology, vol.13, issue.1 ,
DOI : 10.1016/S0955-0674(00)00173-3
Microtubules and actin filaments: dynamic targets for cancer chemotherapy, Current Opinion in Cell Biology, vol.10, issue.1, pp.123-130, 1998. ,
DOI : 10.1016/S0955-0674(98)80095-1
Plant antitumor agents. VI. Isolation and structure of taxol, a novel antileukemic and antitumor agent from Taxus brevifolia, Journal of the American Chemical Society, vol.93, issue.9, pp.2325-2327, 1971. ,
DOI : 10.1021/ja00738a045
Experimental basis for clinical evaluation of anti tumor principles derived from Vinca rosea Linn, J. Lab. Clin. Med, vol.54, p.830, 1959. ,
Microtubule dynamics: taking aim at a moving target, Chemistry & Biology, vol.2, issue.9, pp.569-573, 1995. ,
DOI : 10.1016/1074-5521(95)90119-1
Mechanism of Action of Antitumor Drugs that Interact with Microtubules and Tubulin, Current Medicinal Chemistry-Anti-Cancer Agents, vol.2, issue.1, pp.1-17, 2002. ,
DOI : 10.2174/1568011023354290
Mitotic block induced in HeLa cells by low concentrations of paclitaxel (Taxol) results in abnormal mitotic exit and apoptotic cell death, Cancer Res, vol.56, pp.816-825, 1996. ,
Gene expression and mitotic exit induced by microtubule-stabilizing drugs, Cancer Res, vol.63, pp.7891-7899, 2003. ,
P-glycoprotein: from genomics to mechanism, Oncogene, vol.22, issue.47, pp.7468-7485, 2003. ,
DOI : 10.1038/sj.onc.1206948
Multiple microtubule alterations are associated with Vinca alkaloid resistance in human leukemia cells, Cancer Res, pp.61-5803, 2001. ,
Mechanism of taxane neurotoxicity, Breast Cancer, vol.7, issue.1, pp.82-85, 2004. ,
DOI : 10.1007/BF02968008
Past and future of the mitotic spindle as an oncology target, Current Opinion in Pharmacology, vol.1, issue.4, pp.370-377, 2001. ,
DOI : 10.1016/S1471-4892(01)00064-9
Microtubules as a target for anticancer drugs, Nature Reviews Cancer, vol.4, issue.4, pp.253-265, 2004. ,
DOI : 10.1038/nrc1317
Functional Analysis of Human Microtubule-based Motor Proteins, the Kinesins and Dyneins, in Mitosis/Cytokinesis Using RNA Interference, Molecular Biology of the Cell, vol.16, issue.7, pp.3187-3199, 2005. ,
DOI : 10.1091/mbc.E05-02-0167
Kinesin superfamily proteins and their various functions and dynamics, Experimental Cell Research, vol.301, issue.1, pp.50-59, 2004. ,
DOI : 10.1016/j.yexcr.2004.08.010
All kinesin superfamily protein, KIF, genes in mouse and human, Proc. Natl. Acad. Sci, pp.7004-7011, 2001. ,
DOI : 10.1073/pnas.111145398
Dynamics of the mitotic spindle ? potential therapeutic targets, Prog. Cell Cycle Res, vol.5, pp.349-360, 2003. ,
Mitotic Kinesins: Prospects for Antimitotic Drug Discovery, Current Topics in Medicinal Chemistry, vol.5, issue.2, pp.127-145, 2005. ,
DOI : 10.2174/1568026053507697
Phosphorylation by p34cdc2 regulates spindle association of human Eg5, a kinesin-related motor essential for bipolar spindle formation in vivo, Cell, vol.83, pp.1159-1169, 1995. ,
Expanding the role of HsEg5 within the mitotic and post-mitotic phases of the cell cycle, J. Cell Sci, vol.111, pp.2551-2561, 1998. ,
Expression of the mitotic motor protein Eg5 in postmitotic neurons: Implications for neuronal development, J. Neurosci, vol.18, pp.7822-7835, 1998. ,
Targeting the kinesin Eg5 to monitor siRNA transfection in mammalian cells, Biotechniques, vol.33, pp.1244-1248, 2002. ,
Antitumor Activity of a Kinesin Inhibitor, Cancer Research, vol.64, issue.9, pp.3276-3280, 2004. ,
DOI : 10.1158/0008-5472.CAN-03-3839
Identification of novel antimitotic agents acting at the tubulin level by computer-assisted evaluation of differential cytotoxicity data, Cancer Res, vol.52, pp.3892-3900, 1992. ,
In vitro screening for inhibitors of the human mitotic kinesin Eg5 with antimitotic and antitumor activities, Mol. Cancer Ther, vol.3, pp.1079-1090, 2004. ,
Inhibition of a Mitotic Motor Protein: Where, How, and Conformational Consequences, Journal of Molecular Biology, vol.335, issue.2, pp.547-554, 2003. ,
DOI : 10.1016/j.jmb.2003.10.074
Small Molecule Inhibitor of Mitotic Spindle Bipolarity Identified in a Phenotype-Based Screen, Science, vol.286, issue.5441, pp.971-974, 1999. ,
DOI : 10.1126/science.286.5441.971
Strityl-L-cysteine is a reversible, tight binding inhibitor of the human kinesin Eg5 that specifically blocks mitotic progression, J. Biol. Chem, vol.30, pp.17559-17569, 2006. ,
Proteome analysis of apoptotic cells, Mass Spectrometry Reviews, vol.290, issue.5, pp.333-349, 2004. ,
DOI : 10.1002/mas.10079
A Global Approach Combining Proteome Analysis and Phenotypic Screening with RNA Interference Yields Novel Apoptosis Regulators, Molecular & Cellular Proteomics, vol.4, issue.1, pp.44-55, 2005. ,
DOI : 10.1074/mcp.M400089-MCP200
Two-dimensional electrophoresis of proteins: An updated protocol and implications for a functional analysis of the genome, Electrophoresis, vol.8, issue.1, pp.1034-1059, 1995. ,
DOI : 10.1002/elps.11501601175
A two dimensional electrophoresis database of a human Jurkat T-cell line, Electrophoresis, vol.21, issue.13, pp.2713-2720, 2000. ,
DOI : 10.1002/1522-2683(20000701)21:13<2713::AID-ELPS2713>3.0.CO;2-U
Blue silver: A very sensitive colloidal Coomassie G-250 staining for proteome analysis, ELECTROPHORESIS, vol.25, issue.9, pp.1327-1333, 2004. ,
DOI : 10.1002/elps.200305844
Analysis of high-resolution two-dimensional electrophoresis of differentiation-dependent alterations in cytosolic protein pattern of HL-60 leukemic cells, Journal of Biochemical and Biophysical Methods, vol.21, issue.1, pp.47-58, 1990. ,
DOI : 10.1016/0165-022X(90)90044-D
Peptide mass fingerprinting, Methods, vol.35, issue.3, pp.237-247, 2005. ,
DOI : 10.1016/j.ymeth.2004.08.015
Probability-based protein identification by searching sequence databases using mass spectrometry data, Electrophoresis, vol.447, issue.18, pp.3551-3567, 1999. ,
DOI : 10.1002/(SICI)1522-2683(19991201)20:18<3551::AID-ELPS3551>3.0.CO;2-2
The role of cyclin synthesis and degradation in the control of maturation promoting factor activity, Nature, vol.339, issue.6222, pp.280-286, 1989. ,
DOI : 10.1038/339280a0
Mitosis-specific phosphorylation of histone H3 initiates primarily within pericentromeric heterochromatin during G2 and spreads in an ordered fashion coincident with mitotic chromosome condensation, Chromosoma, vol.106, issue.6, pp.348-360, 1997. ,
DOI : 10.1007/s004120050256
Kinetochore localisation and phosphorylation of the mitotic checkpoint components Bub1 and BubR1 are differentially regulated by spindle events in human cells, J. Cell Sci, vol.114, pp.4385-4395, 2001. ,
The mitotic serine/threonine kinase Aurora2/AIK is regulated by phosphorylation and degradation, Oncogene, vol.19, issue.42, pp.4906-4916, 2000. ,
DOI : 10.1038/sj.onc.1203847
Differential effects of monastrol in two human cell lines, Cellular and Molecular Life Sciences, vol.61, issue.16, pp.61-2060, 2004. ,
DOI : 10.1007/s00018-004-4074-3
Mitotic Kinesin Inhibitors Induce Mitotic Arrest and Cell Death in Taxol-resistant and -sensitive Cancer Cells, Journal of Biological Chemistry, vol.280, issue.12, pp.11569-11577, 2005. ,
DOI : 10.1074/jbc.M413471200
Induction of apoptosis by an inhibitor of the mitotic kinesin KSP requires both activation of the spindle assembly checkpoint and mitotic slippage, Cancer Cell, vol.8, issue.1, pp.49-59, 2005. ,
DOI : 10.1016/j.ccr.2005.06.003
Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells, Molecular Cancer Therapeutics, vol.4, issue.9, pp.1388-1398, 2005. ,
DOI : 10.1158/1535-7163.MCT-05-0152
Defying death after DNA damage, Nature, vol.407, pp.777-783, 2000. ,
Bcl-2-family proteins and the role of mitochondria in apoptosis, Current Opinion in Cell Biology, vol.15, issue.6, pp.691-699, 2003. ,
DOI : 10.1016/j.ceb.2003.10.004
Death receptors in chemotherapy and cancer, Oncogene, vol.23, issue.16, pp.2950-2966, 2004. ,
DOI : 10.1038/sj.onc.1207558
Caspase-specific and nonspecific in vivo protein processing during Fas-induced apoptosis, Nature Methods, vol.267, issue.10, pp.771-777, 2005. ,
DOI : 10.1046/j.1525-1373.1999.d01-11.x
Chaperones get in touch: the Hip-Hop connection, Trends in Biochemical Sciences, vol.22, issue.3, pp.87-92, 1997. ,
DOI : 10.1016/S0968-0004(97)01005-0
Regulation of the heat shock conjugate Hsc70 in the mammalian cell: The characterization of the anti-apoptotic protein BAG-1 provides novel insights, Biol. Chem, vol.379, pp.269-274, 1998. ,
The translationally controlled tumour protein (TCTP), The International Journal of Biochemistry & Cell Biology, vol.36, issue.3, pp.379-385, 2004. ,
DOI : 10.1016/S1357-2725(03)00213-9
Stabilization and Enhancement of the Antiapoptotic Activity of Mcl-1 by TCTP, Molecular and Cellular Biology, vol.25, issue.8, pp.3117-3126, 2005. ,
DOI : 10.1128/MCB.25.8.3117-3126.2005
An N-terminal region of translationally controlled tumor protein is required for its antiapoptotic activity, Oncogene, vol.97, issue.30, pp.4778-4788, 2005. ,
DOI : 10.1038/sj.onc.1208666
The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x, The Journal of Cell Biology, vol.19, issue.7, pp.929-939, 2007. ,
DOI : 10.1074/jbc.274.41.29202
The growth-related, translationally controlled protein P23 has properties of a tubulin binding protein and associates transiently with microtubules during the cell cycle, J. Cell. Sci, vol.112, pp.1257-1271, 1999. ,
Plk Phosphorylation Regulates the Microtubule-Stabilizing Protein TCTP, Molecular and Cellular Biology, vol.22, issue.17, pp.6209-6221, 2002. ,
DOI : 10.1128/MCB.22.17.6209-6221.2002
A target for Src in mitosis, Nature, vol.368, issue.6474, pp.871-874, 1994. ,
DOI : 10.1038/368871a0
An RNA-binding protein associated with Src through its SH2 and SH3 domains in mitosis, Nature, vol.368, issue.6474, pp.867-871, 1994. ,
DOI : 10.1038/368867a0
A conserved Mis12 centromere complex is linked to heterochromatic HP1 and outer kinetochore protein Zwint-1, Nature Cell Biology, vol.11, issue.11, pp.1135-1141, 2004. ,
DOI : 10.1002/(SICI)1522-2683(19991201)20:18<3551::AID-ELPS3551>3.0.CO;2-2
Proteome analysis of nuclear matrix proteins during apoptotic chromatin condensation, Cell Death and Differentiation, vol.9, issue.6, pp.671-681, 2002. ,
DOI : 10.1038/sj.cdd.4401010
Mitotic chromatin regulates phosphorylation of Stath- min/Op18, Nature, vol.389, issue.6651, pp.640-643, 1997. ,
DOI : 10.1038/39382
Large-Scale Quantitative Proteomic Study of PUMA-Induced Apoptosis Using Two-Dimensional Liquid Chromatography???Mass Spectrometry Coupled with Amino Acid-Coded Mass Tagging, Journal of Proteome Research, vol.3, issue.6, pp.1191-1200, 2004. ,
DOI : 10.1021/pr049893a
Quantitative proteome analysis of CD95 (Fas/Apo-1)-induced apoptosis by stable isotope labeling with amino acids in cell culture, 2-DE and MALDI-MS, PROTEOMICS, vol.16, issue.2, pp.614-622, 2006. ,
DOI : 10.1002/pmic.200500120
Proteomic analysis reveals a novel role for the actin cytoskeleton in vincristine resistant childhood leukemia ??? Anin vivo study, PROTEOMICS, vol.1010, issue.5, pp.1681-1694, 2006. ,
DOI : 10.1002/pmic.200500417