Ten-year incidence and risk factors of bone fractures in a cohort of treated HIV1-infected adults. - Archive ouverte HAL Access content directly
Journal Articles AIDS Year : 2009

Ten-year incidence and risk factors of bone fractures in a cohort of treated HIV1-infected adults.

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Abstract

In the ANRS CO8 APROCO-COPILOTE cohort of patients treated with combination antiretroviral therapy since 1997-1999, the incidence density of bone fractures was 3.3 for 1000 patient-years [95% confidence interval (CI) = 2.0-4.6]. The rate was 2.9-fold (95% CI = 1.3-6.5) higher among patients with excessive alcohol consumption and 3.6-fold (95% CI = 1.6-8.1) higher in those with hepatitis C virus (HCV) coinfection. Specific monitoring of HCV/HIV-coinfected patients and active promotion of alcohol cessation should be recommended for the prevention of bone fractures.
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Dates and versions

inserm-00374705 , version 1 (25-03-2010)

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Fidéline Collin, Xavier Duval, Vincent Lemoing, Lionel Piroth, Firas Al Kaied, et al.. Ten-year incidence and risk factors of bone fractures in a cohort of treated HIV1-infected adults.: Bone fractures in HIV1 infected patients.. AIDS, 2009, 23 (8), pp.1021-4. ⟨10.1097/QAD.0b013e3283292195⟩. ⟨inserm-00374705⟩
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