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Ten-year incidence and risk factors of bone fractures in a cohort of treated HIV1-infected adults.: Bone fractures in HIV1 infected patients.

Abstract : In the ANRS CO8 APROCO-COPILOTE cohort of patients treated with combination antiretroviral therapy since 1997-1999, the incidence density of bone fractures was 3.3 for 1000 patient-years [95% confidence interval (CI) = 2.0-4.6]. The rate was 2.9-fold (95% CI = 1.3-6.5) higher among patients with excessive alcohol consumption and 3.6-fold (95% CI = 1.6-8.1) higher in those with hepatitis C virus (HCV) coinfection. Specific monitoring of HCV/HIV-coinfected patients and active promotion of alcohol cessation should be recommended for the prevention of bone fractures.
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Submitted on : Thursday, March 25, 2010 - 1:02:20 PM
Last modification on : Wednesday, August 19, 2020 - 11:17:01 AM
Long-term archiving on: : Tuesday, September 28, 2010 - 11:55:36 AM

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Fidéline Collin, Xavier Duval, Vincent Lemoing, Lionel Piroth, Firas Al Kaied, et al.. Ten-year incidence and risk factors of bone fractures in a cohort of treated HIV1-infected adults.: Bone fractures in HIV1 infected patients.. AIDS, Lippincott, Williams & Wilkins, 2009, 23 (8), pp.1021-4. ⟨10.1097/QAD.0b013e3283292195⟩. ⟨inserm-00374705⟩

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