Multiple Myeloma, New England Journal of Medicine, vol.351, issue.18, pp.1860-1873, 2004. ,
DOI : 10.1056/NEJMra041875
URL : https://hal.archives-ouvertes.fr/hal-00557757
Measurement of apoptosis and proliferation of bone marrow plasma cells in patients with plasma cell proliferative disorders, British Journal of Haematology, vol.97, issue.1, pp.131-137, 1999. ,
DOI : 10.1002/(SICI)1097-0320(19960615)26:2<113::AID-CYTO3>3.0.CO;2-H
Low plasma cell 3(H) thymidine incorporation in monoclonal gammopathy of undetermined significance (MGUS), smouldering myeloma and remission phase myeloma: a reliable indicator of patients not requiring therapy, British Journal of Haematology, vol.70, issue.4, pp.689-696, 1984. ,
DOI : 10.1016/0002-9343(78)90522-3
Plasma cell labeling index and beta 2-microglobulin predict survival independent of thymidine kinase and C-reactive protein in multiple myeloma, Blood, vol.81, pp.3382-3387, 1993. ,
Delineation of distinct subgroups of multiple myeloma and a model for clonal evolution based on interphase cytogenetics, Genes, Chromosomes and Cancer, vol.40, issue.2, pp.194-203, 2005. ,
DOI : 10.1002/gcc.20231
Genetics and Cytogenetics of Multiple Myeloma: A Workshop Report, Cancer Research, vol.64, issue.4, pp.1546-1558, 2004. ,
DOI : 10.1158/0008-5472.CAN-03-2876
Mitotic mechanics: the auroras come into view, Current Opinion in Cell Biology, vol.15, issue.6, pp.672-683, 2003. ,
DOI : 10.1016/j.ceb.2003.10.013
On the role of aurora-A in centrosome function, Oncogene, vol.21, issue.40, pp.6175-6183, 2002. ,
DOI : 10.1038/sj.onc.1205775
URL : https://hal.archives-ouvertes.fr/inserm-00966247
Aurora-kinase inhibitors as anticancer agents, Nature Reviews Cancer, vol.64, issue.12, pp.927-936, 2004. ,
DOI : 10.1038/sj.onc.1207593
Roles of Aurora Kinases in Mitosis and Tumorigenesis, Molecular Cancer Research, vol.5, issue.1, pp.1-10, 2007. ,
DOI : 10.1158/1541-7786.MCR-06-0208
The cellular geography of aurora kinases, Nature Reviews Molecular Cell Biology, vol.4, issue.11, pp.842-854, 2003. ,
DOI : 10.1038/nrm1245
A homologue of Drosophila aurora kinase is oncogenic and amplified in human colorectal cancers, The EMBO Journal, vol.17, issue.11, pp.3052-3065, 1998. ,
DOI : 10.1093/emboj/17.11.3052
Expression of Aurora A (but Not Aurora B) Is Predictive of Survival in Breast Cancer, Clinical Cancer Research, vol.14, issue.14, pp.4455-4462, 2008. ,
DOI : 10.1158/1078-0432.CCR-07-5268
Aurora kinases, aneuploidy and cancer, a coincidence or a real link?, Trends in Cell Biology, vol.15, issue.5, pp.241-250, 2005. ,
DOI : 10.1016/j.tcb.2005.03.004
URL : https://hal.archives-ouvertes.fr/inserm-00966568
Differential Functions of the Aurora-B and Aurora-C Kinases in Mammalian Spermatogenesis, Molecular Endocrinology, vol.21, issue.3, pp.726-739, 2007. ,
DOI : 10.1210/me.2006-0332
Aurora kinases: shining lights on the therapeutic horizon?, Oncogene, vol.64, issue.32, pp.5005-5015, 2005. ,
DOI : 10.1038/sj.onc.1208153
Mutations in aurora prevent centrosome separation leading to the formation of monopolar spindles, Cell, vol.81, issue.1, pp.95-105, 1995. ,
DOI : 10.1016/0092-8674(95)90374-7
VX-680 Inhibits Aurora A and Aurora B Kinase Activity in Human Cells, Cell Cycle, vol.6, issue.22, pp.2846-2854, 2007. ,
DOI : 10.4161/cc.6.22.4940
Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores, The Journal of Cell Biology, vol.114, issue.2, pp.267-280, 2003. ,
DOI : 10.1038/2496
The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore???microtubule attachment and in maintaining the spindle assembly checkpoint, The Journal of Cell Biology, vol.114, issue.21, pp.281-294, 2003. ,
DOI : 10.1073/pnas.96.20.11335
Validating Aurora B as an anti-cancer drug target, Journal of Cell Science, vol.119, issue.17, pp.3664-3675, 2006. ,
DOI : 10.1242/jcs.03145
Aurora A kinase RNAi and small molecule inhibition of Aurora kinases with VE-465 induce apoptotic death in multiple myeloma cells, Leukemia & Lymphoma, vol.93, issue.3, pp.559-569, 2008. ,
DOI : 10.1038/ncb1309
The selective Aurora B kinase inhibitor AZD1152 is a potential new treatment for multiple myeloma, British Journal of Haematology, vol.24, issue.18, pp.295-302, 2008. ,
DOI : 10.1182/blood-2007-02-073700
Targeting aurora kinases as therapy in multiple myeloma, Blood, vol.109, issue.9, pp.3915-3921, 2007. ,
DOI : 10.1182/blood-2006-07-037671
International Staging System for Multiple Myeloma, Journal of Clinical Oncology, vol.23, issue.15, pp.3412-3420, 2005. ,
DOI : 10.1200/JCO.2005.04.242
Staging and cinetics of Multiple Myeloma, Semin.Oncol, vol.13, pp.300-309, 1986. ,
CRITERIA FOR EVALUATING DISEASE RESPONSE AND PROGRESSION IN PATIENTS WITH MULTIPLE MYELOMA TREATED BY HIGH-DOSE THERAPY AND HAEMOPOIETIC STEM CELL TRANSPLANTATION, British Journal of Haematology, vol.88, issue.(Suppl. 2), pp.1115-1123, 1998. ,
DOI : 10.1046/j.1365-2141.1998.00930.x
Joint HOVON-50/GMMG-HD3 randomized trial on the effect of thalidomide as part of a high-dose therapy regimen and as maintenance treatment for newly diagnosed myeloma patients, Annals of Hematology, vol.82, issue.10, pp.654-659, 2003. ,
DOI : 10.1007/s00277-003-0685-2
Total therapy 2 without thalidomide in comparison with total therapy 1: role of intensified induction and posttransplantation consolidation therapies, Blood, vol.107, issue.7, pp.2633-2638, 2006. ,
DOI : 10.1182/blood-2005-10-4084
Heparanase influences expression and shedding of syndecan-1, and its expression by the bone marrow environment is a bad prognostic factor in multiple myeloma, Blood, vol.109, issue.11, pp.4914-4923, 2007. ,
DOI : 10.1182/blood-2006-08-043232
URL : https://hal.archives-ouvertes.fr/inserm-00136105
The level of TACI gene expression in myeloma cells is associated with a signature of microenvironment dependence versus a plasmablastic signature, Blood, vol.106, issue.3, pp.1021-1030, 2005. ,
DOI : 10.1182/blood-2004-11-4512
URL : https://hal.archives-ouvertes.fr/inserm-00129406
Reproducible obtaining of human myeloma cell lines as a model for tumor stem cell study in human multiple myeloma, Blood, vol.83, pp.3654-3663, 1994. ,
Agonist anti-gp130 transducer monoclonal antibodies are human myeloma cell survival and growth factors, Leukemia, vol.14, issue.1, pp.188-197, 2000. ,
DOI : 10.1038/sj.leu.2401632
A gp130 interleukin-6 transducer-dependent SCID model of human multiple myeloma, Blood, vol.91, pp.4727-4737, 1998. ,
Generation of polyclonal plasmablasts from peripheral blood B cells: a normal counterpart of malignant plasmablasts, Blood, vol.100, pp.1113-1122, 2002. ,
Bone marrow mesenchymal stem cells are abnormal in multiple myeloma, Leukemia, vol.63, pp.1079-1088, 2007. ,
DOI : 10.1038/sj.leu.2404621
URL : https://hal.archives-ouvertes.fr/inserm-00270565
A New Molecular Classification of Multiple Myeloma Using Gene Expression Profiling and Fluorescence In Situ Hybridisation as Predictor for Event Free Survival, ASH Annual Meeting Abstracts, vol.104, p.73, 2004. ,
Ploidy, as detected by fluorescence in situ hybridization, defines different subgroups in multiple myeloma, Leukemia, vol.19, issue.2, pp.275-278, 2005. ,
DOI : 10.1038/sj.leu.2403586
Expression of EGF-family receptors and amphiregulin in multiple myeloma. Amphiregulin is a growth factor for myeloma cells, Oncogene, vol.83, issue.21, pp.3512-3524, 2005. ,
DOI : 10.1038/sj.onc.1208536
URL : https://hal.archives-ouvertes.fr/inserm-00130206
Identifying intercellular signaling genes expressed in malignant plasma cells by using complementary DNA arrays, Blood, vol.98, issue.3, pp.771-780, 2001. ,
DOI : 10.1182/blood.V98.3.771
JAK2 tyrosine kinase inhibitor tyrphostin AG490 downregulates the mitogen-activated protein kinase (MAPK) and signal transducer and activator of transcription (STAT) pathways and induces apoptosis in myeloma cells, British Journal of Haematology, vol.83, issue.4, pp.823-828, 2000. ,
DOI : 10.1073/pnas.94.13.6764
Bone morphogenetic protein-5, -6 and -7 inhibit growth and induce apoptosis in human myeloma cells, Oncogene, vol.23, pp.3024-3032, 2004. ,
The myeloma cell antigen syndecan-1 is lost by apoptotic myeloma cells, British Journal of Haematology, vol.83, issue.4, pp.637-646, 1998. ,
DOI : 10.1046/j.1365-2141.1996.d01-1811.x
A Model-Based Background Adjustment for Oligonucleotide Expression Arrays, Journal of the American Statistical Association, vol.99, issue.468, pp.909-917, 2004. ,
DOI : 10.1198/016214504000000683
The 'miss rate' for the analysis of gene expression data, Biostatistics, vol.6, issue.1, pp.111-117, 2005. ,
DOI : 10.1093/biostatistics/kxh021
Linear Models and Empirical Bayes Methods for Assessing Differential Expression in Microarray Experiments, Statistical Applications in Genetics and Molecular Biology, vol.3, issue.1, p.3, 2004. ,
DOI : 10.2202/1544-6115.1027
Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing, Journal of the Royal Statistical Society.Series B, vol.57, pp.289-300, 1995. ,