Skip to Main content Skip to Navigation
Journal articles

Self-reported childhood trauma correlates with schizotypal measures in schizophrenia but not bipolar pedigrees.

Abstract : BACKGROUND: Strong evidence supports the association between childhood trauma and psychotic disorders. In two different high-risk populations, we looked for a correlation between the magnitude of schizotypal dimensions and the importance of self-reported childhood trauma.MethodA sample of 138 unaffected first-degree relatives was recruited (67 relatives of schizophrenic probands and 71 relatives of bipolar probands). The relationship between schizotypal dimensions and childhood trauma scores was analyzed by partial correlations. RESULTS: A positive correlation was found between childhood trauma scores and total schizotypal scores in first-degree relatives of schizophrenic subjects but not in first-degree relatives of bipolar probands. This correlation was primarily due to a strong association with the positive dimension of schizotypy. CONCLUSIONS: The significant correlation between childhood trauma and schizotypal dimensions in subjects at high genetic risk for schizophrenia suggests that susceptibility genes for schizophrenia may interact with childhood trauma to induce the emergence of schizotypal dimensions, mainly positive psychotic features.
Document type :
Journal articles
Complete list of metadatas

Cited literature [21 references]  Display  Hide  Download

https://www.hal.inserm.fr/inserm-00368296
Contributor : Georges Guellaen <>
Submitted on : Monday, March 16, 2009 - 9:48:12 AM
Last modification on : Wednesday, August 19, 2020 - 11:16:59 AM
Long-term archiving on: : Tuesday, June 8, 2010 - 11:28:38 PM

Files

inserm-00368296_edited.pdf
Files produced by the author(s)

Identifiers

Collections

Citation

Franck Schürhoff, Audrey Laguerre, Helen Fisher, Bruno Etain, Alexandre Méary, et al.. Self-reported childhood trauma correlates with schizotypal measures in schizophrenia but not bipolar pedigrees.. Psychological Medicine, Cambridge University Press (CUP), 2009, 39 (3), pp.365-70. ⟨10.1017/S0033291708003905⟩. ⟨inserm-00368296⟩

Share

Metrics

Record views

293

Files downloads

1015